ID   A0A0A0MS61_HUMAN        Unreviewed;       208 AA.
AC   A0A0A0MS61;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   16-JAN-2019, entry version 21.
DE   SubName: Full=Izumo sperm-egg fusion protein 4 {ECO:0000313|Ensembl:ENSP00000378709};
GN   Name=IZUMO4 {ECO:0000313|Ensembl:ENSP00000378709};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000378709, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000378709, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000378709}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2014) to UniProtKB.
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DR   EMBL; AC005328; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005259537.2; XM_005259480.3.
DR   UniGene; Hs.424049; -.
DR   SMR; A0A0A0MS61; -.
DR   PeptideAtlas; A0A0A0MS61; -.
DR   Ensembl; ENST00000395296; ENSP00000378709; ENSG00000099840.
DR   GeneID; 113177; -.
DR   UCSC; uc060rhy.1; human.
DR   CTD; 113177; -.
DR   EuPathDB; HostDB:ENSG00000099840.13; -.
DR   HGNC; HGNC:26950; IZUMO4.
DR   OpenTargets; ENSG00000099840; -.
DR   GeneTree; ENSGT00390000015418; -.
DR   OrthoDB; 1110467at2759; -.
DR   GenomeRNAi; 113177; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000099840; Expressed in 142 organ(s), highest expression level in left testis.
DR   ExpressionAtlas; A0A0A0MS61; baseline and differential.
DR   InterPro; IPR029389; IZUMO.
DR   Pfam; PF15005; IZUMO; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:A0A0A0MS61};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     17       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        18    208       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001974203.
SQ   SEQUENCE   208 AA;  23822 MW;  E07791421622566B CRC64;
     MALLLCLVCL TAALAHGCLH CHSNFSKKFS FYRHHVNFKS WWVGDIPVSG ALLTDWSDDT
     MKELHLAIPA KITREKLDQV ATAVYQMMDQ LYQGKMYFPG YFPNELRNIF REQVHLIQNA
     IIESRIDCQH RCGIFQYETI SCNNCTDSHV ACFGYNCESS AQWKSAVQGL LNYINNWHNL
     VSPALRCLEP PHLANLTLED AAECLKQH
//