ID   A0A0A0MRR9_HUMAN        Unreviewed;       140 AA.
AC   A0A0A0MRR9;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   07-NOV-2018, entry version 22.
DE   SubName: Full=Transmembrane protein 273 {ECO:0000313|Ensembl:ENSP00000363266};
GN   Name=TMEM273 {ECO:0000313|Ensembl:ENSP00000363266};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000363266, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000363266, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15164054; DOI=10.1038/nature02462;
RA   Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L.,
RA   Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K.,
RA   Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L.,
RA   Taylor A., Battles J., Bird C.P., Ainscough R., Almeida J.P.,
RA   Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J.,
RA   Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J.,
RA   Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D.,
RA   Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA   Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L.,
RA   Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S.,
RA   Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L.,
RA   Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J.,
RA   Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M.,
RA   Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S.,
RA   Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M.,
RA   Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A.,
RA   Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T.,
RA   Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I.,
RA   Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T.,
RA   Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M.,
RA   Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W.,
RA   Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H.,
RA   Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L.,
RA   Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K.,
RA   Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T.,
RA   Doucette-Stamm L., Beck S., Smith D.R., Rogers J.;
RT   "The DNA sequence and comparative analysis of human chromosome 10.";
RL   Nature 429:375-381(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000363266}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2014) to UniProtKB.
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DR   EMBL; AC084727; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL441885; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENST00000374151; ENSP00000363266; ENSG00000204161.
DR   UCSC; uc057tee.1; human.
DR   EuPathDB; HostDB:ENSG00000204161.13; -.
DR   HGNC; HGNC:27274; TMEM273.
DR   OpenTargets; ENSG00000204161; -.
DR   eggNOG; ENOG410J40J; Eukaryota.
DR   eggNOG; ENOG4111805; LUCA.
DR   GeneTree; ENSGT00390000000409; -.
DR   Proteomes; UP000005640; Chromosome 10.
DR   Bgee; ENSG00000204161; Expressed in 184 organ(s), highest expression level in C1 segment of cervical spinal cord.
DR   ExpressionAtlas; A0A0A0MRR9; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR029395; DUF4514.
DR   PANTHER; PTHR37857; PTHR37857; 1.
DR   Pfam; PF14986; DUF4514; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     17       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        18    140       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001967096.
FT   TRANSMEM     27     48       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   140 AA;  15472 MW;  78FF92B45CB43674 CRC64;
     MLRILFLLDV GGAQVLATGK TPGAEIDFKY ALIGTAVGVA ISAGFLALKI CMIRRHLFDD
     DSSDLKSTPG GLSDTIPLKK RAPRKLQAST LFSFKSLLQC HHCIMEGLFK AKPQFLQKHL
     ARSVQIHQLQ KVKSFPKYAY
//