ID   A0A0A0MRF2_HUMAN        Unreviewed;       263 AA.
AC   A0A0A0MRF2;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   16-JAN-2019, entry version 29.
DE   SubName: Full=Osteoclast-associated immunoglobulin-like receptor {ECO:0000313|Ensembl:ENSP00000351145};
GN   Name=OSCAR {ECO:0000313|Ensembl:ENSP00000351145};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000351145, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000351145, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000351145}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2014) to UniProtKB.
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DR   EMBL; AC245052; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_573399.2; NM_133169.4.
DR   UniGene; Hs.347655; -.
DR   ProteinModelPortal; A0A0A0MRF2; -.
DR   PeptideAtlas; A0A0A0MRF2; -.
DR   PRIDE; A0A0A0MRF2; -.
DR   Ensembl; ENST00000358375; ENSP00000351145; ENSG00000170909.
DR   GeneID; 126014; -.
DR   UCSC; uc061cmc.1; human.
DR   CTD; 126014; -.
DR   EuPathDB; HostDB:ENSG00000170909.13; -.
DR   HGNC; HGNC:29960; OSCAR.
DR   OpenTargets; ENSG00000170909; -.
DR   eggNOG; ENOG410IHKK; Eukaryota.
DR   eggNOG; ENOG411142H; LUCA.
DR   GeneTree; ENSGT00930000150991; -.
DR   OrthoDB; 1327293at2759; -.
DR   GenomeRNAi; 126014; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000170909; Expressed in 88 organ(s), highest expression level in blood.
DR   ExpressionAtlas; A0A0A0MRF2; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 2.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   Pfam; PF13895; Ig_2; 1.
DR   SMART; SM00409; IG; 2.
DR   SUPFAM; SSF48726; SSF48726; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A0A0MRF2,
KW   ECO:0000213|PeptideAtlas:A0A0A0MRF2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    263       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001967220.
FT   DOMAIN       38    121       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      135    215       IG. {ECO:0000259|SMART:SM00409}.
SQ   SEQUENCE   263 AA;  28806 MW;  4DF7E0E4A4E1E866 CRC64;
     MALVLILQLL TLWPLCHTDI TPSVPPASYH PKPWLGAQPA TVVTPGVNVT LRCRAPQPAW
     RFGLFKPGEI APLLFRDVSS ELAEFFLEEV TPAQGGSYRC CYRRPDWGPG VWSQPSDVLE
     LLVTEELPRP SLVALPGPVV GPGANVSLRC AGRLRNMSFV LYREGVAAPL QYRHSAQPWA
     DFTLLGARAP GTYSCYYHTP SAPYVLSQRS EVLVISWEDS GSSDYTRGNL VRLGLAGLVL
     ISLGALVTFD WRSQNRAPAG IRP
//