ID   A0A0A0MR94_HUMAN        Unreviewed;       287 AA.
AC   A0A0A0MR94;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   16-JAN-2019, entry version 25.
DE   SubName: Full=Natural cytotoxicity triggering receptor 1 {ECO:0000313|Ensembl:ENSP00000339515};
GN   Name=NCR1 {ECO:0000313|Ensembl:ENSP00000339515};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000339515, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000339515, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000339515}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2014) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSP00000491177}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2017) to UniProtKB.
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DR   EMBL; AC011476; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC245128; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001138930.2; NM_001145458.2.
DR   UniGene; Hs.97084; -.
DR   ProteinModelPortal; A0A0A0MR94; -.
DR   PRIDE; A0A0A0MR94; -.
DR   Ensembl; ENST00000338835; ENSP00000339515; ENSG00000189430.
DR   Ensembl; ENST00000638974; ENSP00000491346; ENSG00000284113.
DR   Ensembl; ENST00000640169; ENSP00000491177; ENSG00000284208.
DR   GeneID; 9437; -.
DR   UCSC; uc002qie.3; human.
DR   CTD; 9437; -.
DR   EuPathDB; HostDB:ENSG00000189430.12; -.
DR   HGNC; HGNC:6731; NCR1.
DR   OpenTargets; ENSG00000189430; -.
DR   GeneTree; ENSGT00940000153328; -.
DR   OrthoDB; 1327293at2759; -.
DR   ChiTaRS; NCR1; human.
DR   GenomeRNAi; 9437; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000189430; Expressed in 73 organ(s), highest expression level in blood.
DR   ExpressionAtlas; A0A0A0MR94; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 2.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   SMART; SM00409; IG; 2.
DR   SUPFAM; SSF48726; SSF48726; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A0A0MR94,
KW   ECO:0000213|PeptideAtlas:A0A0A0MR94};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    287       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014015975.
FT   TRANSMEM    239    257       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       34    115       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      129    211       IG. {ECO:0000259|SMART:SM00409}.
SQ   SEQUENCE   287 AA;  32600 MW;  729BCA065BE3955A CRC64;
     MSSTLPALLC VGLCLSQRIS AQQQTLPKPF IWAEPHFMVP KEKQVTICCQ GNYGAVEYQL
     HFEGSLFAVD RPKPPERINK VQFYIPDMNS RMAGQYSCIY RVGELWSEPS NLLDLVVTEM
     YDTPTLSVHP GPEVISGEKV TFYCRLDTAT SMFLLLKEGR SSHVQRGYGK VQAEFPLGPV
     TTAHRGTYRC FGSYNNHAWS FPSEPVKLLV TGDIENTSLA PEDPTFPDHA LWDHTAQNLL
     RMGLAFLVLV ALVWFLVEDW LSRKRTRERA SRASTWEGRR RLNTQTL
//