ID   A0A0A0MR14_HUMAN        Unreviewed;       252 AA.
AC   A0A0A0MR14;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   16-JAN-2019, entry version 29.
DE   SubName: Full=Osteoclast-associated immunoglobulin-like receptor {ECO:0000313|Ensembl:ENSP00000304523};
GN   Name=OSCAR {ECO:0000313|Ensembl:ENSP00000304523};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000304523, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000304523, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000304523}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2014) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC245052; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_573398.2; NM_133168.4.
DR   UniGene; Hs.347655; -.
DR   ProteinModelPortal; A0A0A0MR14; -.
DR   SMR; A0A0A0MR14; -.
DR   PeptideAtlas; A0A0A0MR14; -.
DR   PRIDE; A0A0A0MR14; -.
DR   Ensembl; ENST00000351806; ENSP00000304523; ENSG00000170909.
DR   GeneID; 126014; -.
DR   UCSC; uc061cmd.1; human.
DR   CTD; 126014; -.
DR   EuPathDB; HostDB:ENSG00000170909.13; -.
DR   HGNC; HGNC:29960; OSCAR.
DR   OpenTargets; ENSG00000170909; -.
DR   eggNOG; ENOG410IHKK; Eukaryota.
DR   eggNOG; ENOG411142H; LUCA.
DR   GeneTree; ENSGT00930000150991; -.
DR   OrthoDB; 1327293at2759; -.
DR   GenomeRNAi; 126014; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000170909; Expressed in 88 organ(s), highest expression level in blood.
DR   ExpressionAtlas; A0A0A0MR14; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 2.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   Pfam; PF13895; Ig_2; 1.
DR   SMART; SM00409; IG; 2.
DR   SUPFAM; SSF48726; SSF48726; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A0A0MR14,
KW   ECO:0000213|PeptideAtlas:A0A0A0MR14};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    252       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001974155.
FT   DOMAIN       27    110       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      124    204       IG. {ECO:0000259|SMART:SM00409}.
SQ   SEQUENCE   252 AA;  27603 MW;  2B996EAE22852502 CRC64;
     MALVLILQLL TLFPPASYHP KPWLGAQPAT VVTPGVNVTL RCRAPQPAWR FGLFKPGEIA
     PLLFRDVSSE LAEFFLEEVT PAQGGSYRCC YRRPDWGPGV WSQPSDVLEL LVTEELPRPS
     LVALPGPVVG PGANVSLRCA GRLRNMSFVL YREGVAAPLQ YRHSAQPWAD FTLLGARAPG
     TYSCYYHTPS APYVLSQRSE VLVISWEDSG SSDYTRGNLV RLGLAGLVLI SLGALVTFDW
     RSQNRAPAGI RP
//