ID   A0A0A0MQZ0_HUMAN        Unreviewed;       304 AA.
AC   A0A0A0MQZ0;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   16-JAN-2019, entry version 30.
DE   SubName: Full=Natural cytotoxicity triggering receptor 1 {ECO:0000313|Ensembl:ENSP00000291890};
GN   Name=NCR1 {ECO:0000313|Ensembl:ENSP00000291890};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000291890, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000291890, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000291890}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2014) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSP00000491026}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2017) to UniProtKB.
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DR   EMBL; AC011476; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC245128; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_004820.2; NM_004829.6.
DR   UniGene; Hs.97084; -.
DR   ProteinModelPortal; A0A0A0MQZ0; -.
DR   PRIDE; A0A0A0MQZ0; -.
DR   Ensembl; ENST00000291890; ENSP00000291890; ENSG00000189430.
DR   Ensembl; ENST00000638273; ENSP00000491026; ENSG00000284113.
DR   Ensembl; ENST00000638494; ENSP00000492314; ENSG00000284208.
DR   GeneID; 9437; -.
DR   KEGG; hsa:9437; -.
DR   UCSC; uc002qib.3; human.
DR   CTD; 9437; -.
DR   EuPathDB; HostDB:ENSG00000189430.12; -.
DR   HGNC; HGNC:6731; NCR1.
DR   OpenTargets; ENSG00000189430; -.
DR   eggNOG; ENOG410IX2G; Eukaryota.
DR   eggNOG; ENOG4111ACT; LUCA.
DR   GeneTree; ENSGT00940000153328; -.
DR   KO; K06741; -.
DR   OMA; YRSGELW; -.
DR   OrthoDB; 1327293at2759; -.
DR   ChiTaRS; NCR1; human.
DR   GenomeRNAi; 9437; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000189430; Expressed in 73 organ(s), highest expression level in blood.
DR   ExpressionAtlas; A0A0A0MQZ0; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 2.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   SMART; SM00409; IG; 2.
DR   SUPFAM; SSF48726; SSF48726; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A0A0MQZ0,
KW   ECO:0000213|PeptideAtlas:A0A0A0MQZ0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    304       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014015973.
FT   TRANSMEM    256    274       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       34    115       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      129    211       IG. {ECO:0000259|SMART:SM00409}.
SQ   SEQUENCE   304 AA;  34480 MW;  072CB306079E1C9D CRC64;
     MSSTLPALLC VGLCLSQRIS AQQQTLPKPF IWAEPHFMVP KEKQVTICCQ GNYGAVEYQL
     HFEGSLFAVD RPKPPERINK VQFYIPDMNS RMAGQYSCIY RVGELWSEPS NLLDLVVTEM
     YDTPTLSVHP GPEVISGEKV TFYCRLDTAT SMFLLLKEGR SSHVQRGYGK VQAEFPLGPV
     TTAHRGTYRC FGSYNNHAWS FPSEPVKLLV TGDIENTSLA PEDPTFPADT WGTYLLTTET
     GLQKDHALWD HTAQNLLRMG LAFLVLVALV WFLVEDWLSR KRTRERASRA STWEGRRRLN
     TQTL
//