ID   A0A087X0L2_HUMAN        Unreviewed;       239 AA.
AC   A0A087X0L2;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   16-JAN-2019, entry version 31.
DE   SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000483482};
GN   Name=MUC1 {ECO:0000313|Ensembl:ENSP00000483482};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000483482, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000483482, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16710414; DOI=10.1038/nature04727;
RA   Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA   Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.,
RA   Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA   McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA   Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA   Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA   Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA   Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA   Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA   Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA   Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA   Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA   Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA   Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S.,
RA   Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J.,
RA   James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K.,
RA   Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G.,
RA   Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J.,
RA   Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L.,
RA   Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J.,
RA   Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A.,
RA   Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K.,
RA   Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G.,
RA   Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S.,
RA   Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N.,
RA   Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S.,
RA   Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L.,
RA   Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.,
RA   Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T.,
RA   Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R.,
RA   Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P.,
RA   Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D.,
RA   Porter K.M., Prigmore E.;
RT   "The DNA sequence and biological annotation of human chromosome 1.";
RL   Nature 441:315-321(2006).
RN   [2] {ECO:0000213|PubMed:23186163}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=23186163;
RA   Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA   Mohammed S.;
RT   "Toward a comprehensive characterization of a human cancer cell
RT   phosphoproteome.";
RL   J. Proteome Res. 12:260-271(2013).
RN   [3] {ECO:0000313|Ensembl:ENSP00000483482}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2014) to UniProtKB.
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DR   EMBL; AC234582; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001191221.1; NM_001204292.1.
DR   UniGene; Hs.89603; -.
DR   ProteinModelPortal; A0A087X0L2; -.
DR   SMR; A0A087X0L2; -.
DR   EPD; A0A087X0L2; -.
DR   jPOST; A0A087X0L2; -.
DR   PeptideAtlas; A0A087X0L2; -.
DR   PRIDE; A0A087X0L2; -.
DR   Ensembl; ENST00000610359; ENSP00000483482; ENSG00000185499.
DR   GeneID; 4582; -.
DR   UCSC; uc009wpx.4; human.
DR   CTD; 4582; -.
DR   EuPathDB; HostDB:ENSG00000185499.16; -.
DR   HGNC; HGNC:7508; MUC1.
DR   OpenTargets; ENSG00000185499; -.
DR   eggNOG; ENOG410IX6R; Eukaryota.
DR   eggNOG; ENOG410ZQ7Z; LUCA.
DR   GeneTree; ENSGT00710000106874; -.
DR   OrthoDB; 945460at2759; -.
DR   ChiTaRS; MUC1; human.
DR   GenomeRNAi; 4582; -.
DR   Proteomes; UP000005640; Chromosome 1.
DR   Bgee; ENSG00000185499; Expressed in 199 organ(s), highest expression level in body of stomach.
DR   ExpressionAtlas; A0A087X0L2; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|EPD:A0A087X0L2,
KW   ECO:0000213|MaxQB:A0A087X0L2, ECO:0000213|PeptideAtlas:A0A087X0L2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     23       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        24    239       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001832146.
FT   TRANSMEM    143    168       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   239 AA;  25405 MW;  2D7880F01A8FD2BD CRC64;
     MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK
     NAIPAPTTTK SCRETFLKWP GSVVVQLTLA FREGTINVHD VETQFNQYKT EAASRYNLTI
     SDVSVSDVPF PFSAQSGAGV PGWGIALLVL VCVLVALAIV YLIALAVCQC RRKNYGQLDI
     FPARDTYHPM SEYPTYHTHG RYVPPSSTDR SPYEKVSAGN GGSSLSYTNP AVAATSANL
//