ID   A0A087WZ03_HUMAN        Unreviewed;       966 AA.
AC   A0A087WZ03;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   16-JAN-2019, entry version 38.
DE   SubName: Full=Contactin-associated protein-like 3B {ECO:0000313|Ensembl:ENSP00000482254};
GN   Name=CNTNAP3B {ECO:0000313|Ensembl:ENSP00000482254};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000482254, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000482254, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15164053; DOI=10.1038/nature02465;
RA   Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E.,
RA   Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C.,
RA   Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S.,
RA   Babbage A.K., Babbage S., Bagguley C.L., Bailey J., Banerjee R.,
RA   Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P.,
RA   Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W.,
RA   Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G.,
RA   Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M.,
RA   Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W.,
RA   Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A.,
RA   Frankland J.A., French L., Fricker D.G., Garner P., Garnett J.,
RA   Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S.,
RA   Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E.,
RA   Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D.,
RA   Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E.,
RA   Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K.,
RA   Kimberley A.M., King A., Knights A., Laird G.K., Langford C.,
RA   Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M.,
RA   Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S.,
RA   McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J.,
RA   Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R.,
RA   Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M.,
RA   Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M.,
RA   Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A.,
RA   Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P.,
RA   Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W.,
RA   Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.,
RA   Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S.,
RA   Rogers J., Dunham I.;
RT   "DNA sequence and analysis of human chromosome 9.";
RL   Nature 429:369-374(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000482254}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2014) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00122}.
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DR   EMBL; AL953854; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BX649569; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CR788268; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; A0A087WZ03; -.
DR   jPOST; A0A087WZ03; -.
DR   PeptideAtlas; A0A087WZ03; -.
DR   Ensembl; ENST00000619138; ENSP00000482254; ENSG00000154529.
DR   UCSC; uc064thm.1; human.
DR   EuPathDB; HostDB:ENSG00000154529.14; -.
DR   HGNC; HGNC:32035; CNTNAP3B.
DR   OpenTargets; ENSG00000154529; -.
DR   eggNOG; KOG3516; Eukaryota.
DR   eggNOG; ENOG410XPHG; LUCA.
DR   GeneTree; ENSGT00940000160228; -.
DR   ChiTaRS; CNTNAP3B; human.
DR   Proteomes; UP000005640; Chromosome 9.
DR   Bgee; ENSG00000154529; Expressed in 91 organ(s), highest expression level in lower esophagus.
DR   ExpressionAtlas; A0A087WZ03; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   CDD; cd00057; FA58C; 1.
DR   Gene3D; 2.60.120.260; -; 1.
DR   InterPro; IPR028873; CASPR3.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR036056; Fibrinogen-like_C.
DR   InterPro; IPR002181; Fibrinogen_a/b/g_C_dom.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR001791; Laminin_G.
DR   PANTHER; PTHR43925:SF6; PTHR43925:SF6; 2.
DR   Pfam; PF00754; F5_F8_type_C; 1.
DR   Pfam; PF02210; Laminin_G_2; 3.
DR   SMART; SM00231; FA58C; 1.
DR   SMART; SM00282; LamG; 3.
DR   SUPFAM; SSF49785; SSF49785; 1.
DR   SUPFAM; SSF49899; SSF49899; 4.
DR   SUPFAM; SSF56496; SSF56496; 1.
DR   PROSITE; PS50026; EGF_3; 1.
DR   PROSITE; PS01285; FA58C_1; 1.
DR   PROSITE; PS01286; FA58C_2; 1.
DR   PROSITE; PS50022; FA58C_3; 1.
DR   PROSITE; PS51406; FIBRINOGEN_C_2; 1.
DR   PROSITE; PS50025; LAM_G_DOMAIN; 3.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00122};
KW   EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     25       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        26    966       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001832105.
FT   DOMAIN       31    177       F5/8 type C.
FT                                {ECO:0000259|PROSITE:PS50022}.
FT   DOMAIN      183    364       LAM_G_DOMAIN.
FT                                {ECO:0000259|PROSITE:PS50025}.
FT   DOMAIN      370    582       LAM_G_DOMAIN.
FT                                {ECO:0000259|PROSITE:PS50025}.
FT   DOMAIN      490    541       Fibrinogen C-terminal.
FT                                {ECO:0000259|PROSITE:PS51406}.
FT   DOMAIN      699    864       LAM_G_DOMAIN.
FT                                {ECO:0000259|PROSITE:PS50025}.
FT   DOMAIN      865    903       EGF-like. {ECO:0000259|PROSITE:PS50026}.
FT   DISULFID    837    864       {ECO:0000256|PROSITE-ProRule:PRU00122}.
SQ   SEQUENCE   966 AA;  106323 MW;  BB3029EF8A4F7CF2 CRC64;
     MASVAWAVLK VLLLLPTQTW SPVGAGNPPD CDSPLASALP RSSFSSSSEL SSSHGPGFSR
     LNRRDGAGGW TPLVSNKYQW LQIDLGERME VTAVATQGGY GSSDWVTSYL LMFSDGGRNW
     KQYRREESIW GFPGNTNADS VVHYRLQPPF EARFLRFLPL AWNPRGRIGM RIEVYGCAYK
     SEVVYFDGQS ALLYTLDKKP LKPIRDVISL KFKAMQSNGI LLHREGQHGN HITLELIKGK
     LVFFLNSGNA KLPSTIAPVT LTLGSLLDDQ HWHSVLIELL DTQVNFTVDK HTHHFQAKGD
     SSNLDLNFEI SFGGILSPGR SRAFTRKSFH GCLENLYYNG VDVTELAKKH KPQILMMGNV
     SFSCPQPQTV PVTFLSSRSY LALPGNSGED KVSVTFQFRT WNRAGHLLFG ELQRGSGSFV
     LFLKDGKLKL SLFQAGQSPR NVTAGAGLND GQWHSVSFSA KWSHMNVVVD DDTAVQPLVA
     VLIDSGDTYY FGALYEQSCE AHKHRGNPSG LYYIDADGSG PLGPFLVYCN MTDSAWTVVR
     HGGPDAVTLR GAPSGHPLSA VSFAYAAGAG QLRAAVNLAE RCEQRLALRC GTARRPDSRD
     GTPLSWWVGR TNETHTSWGG SLPDAQKCTC GLEGNCIDSQ YYCNCDAGQN EWTSDTIVLS
     QKEHLPVTQI VMTDTGQPHS EADYTLGPLL CRGDKSFWNS ASFNTETSYL HFPAFHGELT
     ADVCFFFKTT VSSGVFMENL GITDFIRIEL RAPTEVTFSF DVGNGPCEVT VQSPTPFNDN
     QWHHVRAERN VKGASLQVDQ LPQKMQPAPA DGHVRLQLNS QLFIGGTATR QRGFLGCIRS
     LQLNGVALDL EERATVTPGV EPGCAGHCST YGHLCRNGGR CREKRRGVTC DCAFSAYDGP
     FCSNEISAYF ATGSSMTYHF QEHYTLSENS SSLVSSLHRD VTLTREMITL SFRTTRTPSL
     LLKFAD
//