ID   A0A087WY35_HUMAN        Unreviewed;       445 AA.
AC   A0A087WY35;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   16-JAN-2019, entry version 28.
DE   SubName: Full=Integrin beta-like protein 1 {ECO:0000313|Ensembl:ENSP00000481484};
GN   Name=ITGBL1 {ECO:0000313|Ensembl:ENSP00000481484};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000481484, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000481484, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057823; DOI=10.1038/nature02379;
RA   Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L.,
RA   Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E.,
RA   Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E.,
RA   Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T.,
RA   Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R.,
RA   Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S.,
RA   Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P.,
RA   Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M.,
RA   Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J.,
RA   Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E.,
RA   Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L.,
RA   Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J.,
RA   Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S.,
RA   Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J.,
RA   Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M.,
RA   King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A.,
RA   Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S.,
RA   Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S.,
RA   Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I.,
RA   Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S.,
RA   Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A.,
RA   Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B.,
RA   Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L.,
RA   Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R.,
RA   Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T.;
RT   "The DNA sequence and analysis of human chromosome 13.";
RL   Nature 428:522-528(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000481484}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2014) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AL139800; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL160153; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL355807; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF511191; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001258684.1; NM_001271755.1.
DR   UniGene; Hs.696554; -.
DR   ProteinModelPortal; A0A087WY35; -.
DR   jPOST; A0A087WY35; -.
DR   PeptideAtlas; A0A087WY35; -.
DR   Ensembl; ENST00000618057; ENSP00000481484; ENSG00000198542.
DR   GeneID; 9358; -.
DR   UCSC; uc010agb.5; human.
DR   CTD; 9358; -.
DR   EuPathDB; HostDB:ENSG00000198542.13; -.
DR   HGNC; HGNC:6164; ITGBL1.
DR   OpenTargets; ENSG00000198542; -.
DR   GeneTree; ENSGT00940000153730; -.
DR   OrthoDB; 18592at2759; -.
DR   GenomeRNAi; 9358; -.
DR   Proteomes; UP000005640; Chromosome 13.
DR   Bgee; ENSG00000198542; Expressed in 206 organ(s), highest expression level in tendon.
DR   ExpressionAtlas; A0A087WY35; baseline and differential.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR013111; EGF_extracell.
DR   InterPro; IPR027070; Integrin_b-like_p1.
DR   InterPro; IPR015812; Integrin_bsu.
DR   PANTHER; PTHR10082; PTHR10082; 2.
DR   PANTHER; PTHR10082:SF3; PTHR10082:SF3; 2.
DR   Pfam; PF07974; EGF_2; 3.
DR   SMART; SM00181; EGF; 4.
DR   PROSITE; PS00243; INTEGRIN_BETA; 6.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:A0A087WY35};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     23       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        24    445       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001832065.
FT   DOMAIN      135    168       EGF-like. {ECO:0000259|SMART:SM00181}.
FT   DOMAIN      181    221       EGF-like. {ECO:0000259|SMART:SM00181}.
FT   DOMAIN      226    262       EGF-like. {ECO:0000259|SMART:SM00181}.
FT   DOMAIN      318    350       EGF-like. {ECO:0000259|SMART:SM00181}.
SQ   SEQUENCE   445 AA;  48546 MW;  764A05D457605FC0 CRC64;
     MRPPGFRNFL LLASSLLFAG LSAVPQSFSP SLRSWPGAAC RLSRAESERR CRAPGQPPGA
     ALCHGRGRCD CGVCICHVTE PGMFFGPLCE CHEWVCETYD GSTCAGTCHC GRCKCDNSDG
     SGLVYGKFCE CDDRECIDDE TEEICGGHGK CYCGNCYCKA GWHGDKCEFQ CDITPWESKR
     RCTSPDGKIC SNRGTCVCGE CTCHDVDPTG DWGDIHGDTC ECDERDCRAV YDRYSDDFCS
     GHGQCNCGRC DCKAGWYGKK CEHPQSCTLS AEESIRKCQG SSDLPCSGRG KCECGKCTCY
     PPGDRRVYGK TCECDDRRCE DLDGVVCGGH GTCSCGRCVC ERGWFGKLCQ HPRKCNMTEE
     QSKNLCESAD GILCSGKGSC HCGKCICSAE EWYISGEFCD CDDRDCDKHD GLICTGNGIC
     SCGNCECWDG WNGNACEIWL GSEYP
//