ID   A0A087WWY2_HUMAN        Unreviewed;       244 AA.
AC   A0A087WWY2;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   16-JAN-2019, entry version 27.
DE   SubName: Full=Folate receptor beta {ECO:0000313|Ensembl:ENSP00000480592};
GN   Name=FOLR2 {ECO:0000313|Ensembl:ENSP00000480592};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000480592, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000480592, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000480592}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2014) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AP000593; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF455414; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; A0A087WWY2; -.
DR   SMR; A0A087WWY2; -.
DR   jPOST; A0A087WWY2; -.
DR   PeptideAtlas; A0A087WWY2; -.
DR   Ensembl; ENST00000619261; ENSP00000480592; ENSG00000165457.
DR   UCSC; uc058ezz.1; human.
DR   EuPathDB; HostDB:ENSG00000165457.13; -.
DR   HGNC; HGNC:3793; FOLR2.
DR   OpenTargets; ENSG00000165457; -.
DR   eggNOG; ENOG410IFFP; Eukaryota.
DR   eggNOG; ENOG4111IU4; LUCA.
DR   GeneTree; ENSGT00940000153758; -.
DR   ChiTaRS; FOLR2; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000165457; Expressed in 215 organ(s), highest expression level in esophagus.
DR   ExpressionAtlas; A0A087WWY2; baseline and differential.
DR   GO; GO:0005542; F:folic acid binding; IEA:InterPro.
DR   GO; GO:0061714; F:folic acid receptor activity; IEA:InterPro.
DR   GO; GO:1904447; P:folate import across plasma membrane; IEA:InterPro.
DR   InterPro; IPR004269; Folate_rcpt.
DR   InterPro; IPR018143; Folate_rcpt-like.
DR   InterPro; IPR032937; FOLR2.
DR   PANTHER; PTHR10517; PTHR10517; 1.
DR   PANTHER; PTHR10517:SF8; PTHR10517:SF8; 1.
DR   Pfam; PF03024; Folate_rec; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A087WWY2,
KW   ECO:0000213|PeptideAtlas:A0A087WWY2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     38       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        39    244       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001832025.
FT   DOMAIN       47    111       Folate_rec. {ECO:0000259|Pfam:PF03024}.
SQ   SEQUENCE   244 AA;  26181 MW;  CB2D098F92BD8C9B CRC64;
     MLPAATEVQL RLQGQKDMVW KWMPLLLLLV CVATMCSAQD RTDLLNVCMD AKHHKTKPGP
     EDKLHDQCSP WKKNACCTAS TSQELHKDTS RLYNFNWDHC GKMEPACSAT SSRTPVSMSA
     HQPGALDPAG IRAGAKNASW MCPYAKRTVS AGGRIVTPPT RARATGTEDG TGPQELTSAQ
     LGLSAAPLSP TSPLQLPFVK ASGVTHTRSA TTAEGAAAAS RCGLIQPRAT PTRKWRGSML
     QPCM
//