ID   A0A087WWS6_HUMAN        Unreviewed;       190 AA.
AC   A0A087WWS6;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   16-JAN-2019, entry version 33.
DE   SubName: Full=Interferon alpha-1/13 {ECO:0000313|Ensembl:ENSP00000480467};
GN   Name=IFNA13 {ECO:0000313|Ensembl:ENSP00000480467};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000480467, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000480467, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15164053; DOI=10.1038/nature02465;
RA   Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E.,
RA   Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C.,
RA   Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S.,
RA   Babbage A.K., Babbage S., Bagguley C.L., Bailey J., Banerjee R.,
RA   Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P.,
RA   Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W.,
RA   Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G.,
RA   Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M.,
RA   Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W.,
RA   Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A.,
RA   Frankland J.A., French L., Fricker D.G., Garner P., Garnett J.,
RA   Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S.,
RA   Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E.,
RA   Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D.,
RA   Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E.,
RA   Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K.,
RA   Kimberley A.M., King A., Knights A., Laird G.K., Langford C.,
RA   Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M.,
RA   Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S.,
RA   McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J.,
RA   Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R.,
RA   Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M.,
RA   Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M.,
RA   Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A.,
RA   Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P.,
RA   Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W.,
RA   Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.,
RA   Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S.,
RA   Rogers J., Dunham I.;
RT   "DNA sequence and analysis of human chromosome 9.";
RL   Nature 429:369-374(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000480467}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2014) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|SAAS:SAAS00135286}.
CC   -!- SIMILARITY: Belongs to the alpha/beta interferon family.
CC       {ECO:0000256|RuleBase:RU000436, ECO:0000256|SAAS:SAAS00562792}.
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DR   EMBL; AL353732; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_008831.3; NM_006900.3.
DR   UniGene; Hs.37026; -.
DR   UniGene; Hs.533471; -.
DR   ProteinModelPortal; A0A087WWS6; -.
DR   SMR; A0A087WWS6; -.
DR   STRING; 9606.ENSP00000394494; -.
DR   PaxDb; A0A087WWS6; -.
DR   PRIDE; A0A087WWS6; -.
DR   Ensembl; ENST00000610660; ENSP00000480467; ENSG00000233816.
DR   GeneID; 3447; -.
DR   KEGG; hsa:3447; -.
DR   UCSC; uc003zpa.3; human.
DR   CTD; 3447; -.
DR   EuPathDB; HostDB:ENSG00000233816.3; -.
DR   HGNC; HGNC:5419; IFNA13.
DR   eggNOG; ENOG410IR8X; Eukaryota.
DR   eggNOG; ENOG4110Q1A; LUCA.
DR   GeneTree; ENSGT00940000153163; -.
DR   KO; K05414; -.
DR   OMA; ISVHREI; -.
DR   OrthoDB; 1358010at2759; -.
DR   PhylomeDB; A0A087WWS6; -.
DR   GenomeRNAi; 3447; -.
DR   Proteomes; UP000005640; Chromosome 9.
DR   Bgee; ENSG00000233816; Expressed in 25 organ(s), highest expression level in corpus callosum.
DR   ExpressionAtlas; A0A087WWS6; baseline and differential.
DR   GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR   GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
DR   GO; GO:0005126; F:cytokine receptor binding; IEA:InterPro.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   CDD; cd00095; IFab; 1.
DR   InterPro; IPR009079; 4_helix_cytokine-like_core.
DR   InterPro; IPR000471; Interferon_alpha/beta/delta.
DR   PANTHER; PTHR11691; PTHR11691; 1.
DR   Pfam; PF00143; Interferon; 1.
DR   PRINTS; PR00266; INTERFERONAB.
DR   SMART; SM00076; IFabd; 1.
DR   SUPFAM; SSF47266; SSF47266; 1.
DR   PROSITE; PS00252; INTERFERON_A_B_D; 1.
PE   1: Evidence at protein level;
KW   Antiviral defense {ECO:0000256|RuleBase:RU000436,
KW   ECO:0000256|SAAS:SAAS00065439};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Cytokine {ECO:0000256|RuleBase:RU000436,
KW   ECO:0000256|SAAS:SAAS00449409};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS00135285};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A087WWS6,
KW   ECO:0000213|PeptideAtlas:A0A087WWS6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Secreted {ECO:0000256|SAAS:SAAS00135283};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     24       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        25    190       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001832002.
SQ   SEQUENCE   190 AA;  21828 MW;  822F244732033EB3 CRC64;
     MMASPFALLM ALVVLSCKSS CSLGCDLPET HSLDNRRTLM LLAQMSRISP SSCLMDRHDF
     GFPQEEFDGN QFQKAPAISV LHELIQQIFN LFTTKDSSAA WDEDLLDKFC TELYQQLNDL
     EACVMQEERV GETPLMNADS ILAVKKYFRR ITLYLTEKKY SPCAWEVVRA EIMRSLSLST
     NLQERLRRKE
//