ID   A0A087WVT0_HUMAN        Unreviewed;       565 AA.
AC   A0A087WVT0;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   05-DEC-2018, entry version 20.
DE   SubName: Full=Anthrax toxin receptor-like {ECO:0000313|Ensembl:ENSP00000479655};
GN   Name=ANTXRL {ECO:0000313|Ensembl:ENSP00000479655};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000479655, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000479655, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15164054; DOI=10.1038/nature02462;
RA   Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L.,
RA   Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K.,
RA   Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L.,
RA   Taylor A., Battles J., Bird C.P., Ainscough R., Almeida J.P.,
RA   Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J.,
RA   Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J.,
RA   Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D.,
RA   Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA   Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L.,
RA   Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S.,
RA   Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L.,
RA   Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J.,
RA   Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M.,
RA   Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S.,
RA   Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M.,
RA   Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A.,
RA   Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T.,
RA   Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I.,
RA   Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T.,
RA   Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M.,
RA   Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W.,
RA   Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H.,
RA   Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L.,
RA   Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K.,
RA   Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T.,
RA   Doucette-Stamm L., Beck S., Smith D.R., Rogers J.;
RT   "The DNA sequence and comparative analysis of human chromosome 10.";
RL   Nature 429:375-381(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000479655}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2014) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC244230; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL450388; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; A0A087WVT0; -.
DR   PeptideAtlas; A0A087WVT0; -.
DR   Ensembl; ENST00000622632; ENSP00000479655; ENSG00000274209.
DR   UCSC; uc057szv.1; human.
DR   EuPathDB; HostDB:ENSG00000274209.4; -.
DR   HGNC; HGNC:27277; ANTXRL.
DR   OpenTargets; ENSG00000274209; -.
DR   eggNOG; ENOG410J9D0; Eukaryota.
DR   eggNOG; ENOG410XUV2; LUCA.
DR   GeneTree; ENSGT00940000157727; -.
DR   ChiTaRS; ANTXRL; human.
DR   Proteomes; UP000005640; Chromosome 10.
DR   Bgee; ENSG00000274209; Expressed in 66 organ(s), highest expression level in right testis.
DR   ExpressionAtlas; A0A087WVT0; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   Gene3D; 3.40.50.410; -; 1.
DR   InterPro; IPR017360; Anthrax_toxin_rcpt.
DR   InterPro; IPR008400; Anthrax_toxin_rcpt_extracel.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR16059; PTHR16059; 1.
DR   Pfam; PF05587; Anth_Ig; 1.
DR   Pfam; PF00092; VWA; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:A0A087WVT0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     27       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        28    565       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001831975.
FT   TRANSMEM    354    375       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       76    246       VWFA. {ECO:0000259|PROSITE:PS50234}.
SQ   SEQUENCE   565 AA;  62846 MW;  0E8F9C6B4796E306 CRC64;
     MGSHESLGPY FLVFLLLLLL PPPLFRAGSL RYHGPDWRIF HRLALGSRRA HHHHGPGWRQ
     HWRQGQAGHR CQGSFDLYFI LDKSGSVNNN WIDLYMWVEE TVARFQSPNI RMCFITYSTD
     GQTVLPLTSD KNRIKNGLDQ LQKIVPDGHT FMQAGFRKAI QQIESFNSGN KVPSMIIAMT
     DGELVAHAFQ DTLREAQKAR KLGANVYTLG VADYNLDQIT AIADSPGHVF AVENGFKALR
     STIDALTSKV CLDVTSVEPS SECVGEPYHV VIHGNGFQNL KKRDEVICRF IFNESTIIDE
     KPTSIDNNSM NCPGPKLEKP GEEYSIEVSL NKGKTFFKSN VSITSTTCGI FRNWLYFVPL
     LLLVPLLLCC VWRLCRKQTV KEPPPVQKPE KEPEQEKPPS PPPPPPPPPP PLPPPPPAPV
     NTCPTVIICC CGCQGVGGMR RIEGNLDTFC DLSHASCHQV PWMCCQSRDQ GRYLSLALAQ
     SQYAQAPCCP RICFPHSQEP KDLPETQPGV LFPSTDSVQP KELPSTQPGV PRCCRCCPHC
     SGTRQNPLCH SPPQSPTSKA PNTQD
//