ID   A0A087WVM2_HUMAN        Unreviewed;       437 AA.
AC   A0A087WVM2;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   16-JAN-2019, entry version 29.
DE   SubName: Full=CD177 antigen {ECO:0000313|Ensembl:ENSP00000479536};
GN   Name=CD177 {ECO:0000313|Ensembl:ENSP00000479536};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000479536, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000479536, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000479536}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2014) to UniProtKB.
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DR   EMBL; AC005392; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMYH02036160; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_065139.2; NM_020406.3.
DR   UniGene; Hs.232165; -.
DR   ProteinModelPortal; A0A087WVM2; -.
DR   SMR; A0A087WVM2; -.
DR   jPOST; A0A087WVM2; -.
DR   PeptideAtlas; A0A087WVM2; -.
DR   PRIDE; A0A087WVM2; -.
DR   Ensembl; ENST00000618265; ENSP00000479536; ENSG00000204936.
DR   GeneID; 57126; -.
DR   KEGG; hsa:57126; -.
DR   UCSC; uc032hyu.2; human.
DR   CTD; 57126; -.
DR   EuPathDB; HostDB:ENSG00000204936.9; -.
DR   HGNC; HGNC:30072; CD177.
DR   OpenTargets; ENSG00000204936; -.
DR   eggNOG; ENOG410J207; Eukaryota.
DR   eggNOG; ENOG4111D7X; LUCA.
DR   GeneTree; ENSGT00530000063351; -.
DR   KO; K06552; -.
DR   OMA; GQVCQET; -.
DR   OrthoDB; 1103796at2759; -.
DR   GenomeRNAi; 57126; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000204936; Expressed in 111 organ(s), highest expression level in blood.
DR   ExpressionAtlas; A0A087WVM2; baseline and differential.
DR   InterPro; IPR016054; LY6_UPA_recep-like.
DR   Pfam; PF00021; UPAR_LY6; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A087WVM2,
KW   ECO:0000213|PeptideAtlas:A0A087WVM2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    437       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001831972.
FT   DOMAIN      133    207       UPAR/Ly6. {ECO:0000259|Pfam:PF00021}.
FT   DOMAIN      325    394       UPAR/Ly6. {ECO:0000259|Pfam:PF00021}.
SQ   SEQUENCE   437 AA;  46381 MW;  FDA06DDFCD610575 CRC64;
     MSAVLLLALL GFILPLPGVQ ALLCQFGTVQ HVWKVSDLPR QWTPKNTSCD SGLGCQDTLM
     LIESGPQVSL VLSKGCTEAK DQEPRVTEHR MGPGLSLISY TFVCRQEDFC NNLVNSLPLW
     APQPPADPGS LRCPVCLSME GCLEGTTEEI CPKGTTHCYD GLLRLRGGGI FSNLRVQGCM
     PQPVCNLLNG TQEIGPVGMT ENCDMKDFLT CHRGTTIMTH GNLAQEPTDW TTSNTEMCEV
     GQVCQETLLL LDVGLTSTLV GTKGCSTVGA QNSQKTTIHS APPGVLVASY THFCSSDLCN
     SASSSSVLLN SLPPQAAPVP GDRQCPTCVQ PLGTCSSGSP RMTCPRGATH CYDGYIHLSG
     GGLSTKMSIQ GCVAQPSSFL LNHTRQIGIF SAREKRDVQP PASQHEGGGA EGLESLTWGV
     GLALAPALWW GVVCPSC
//