ID   A0A087WUT8_HUMAN        Unreviewed;       477 AA.
AC   A0A087WUT8;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   16-JAN-2019, entry version 26.
DE   SubName: Full=Chondroitin sulfate proteoglycan 5 {ECO:0000313|Ensembl:ENSP00000478923};
GN   Name=CSPG5 {ECO:0000313|Ensembl:ENSP00000478923};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000478923, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000478923, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000478923}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2014) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC099778; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC112512; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001193873.1; NM_001206944.1.
DR   UniGene; Hs.45127; -.
DR   ProteinModelPortal; A0A087WUT8; -.
DR   PeptideAtlas; A0A087WUT8; -.
DR   PRIDE; A0A087WUT8; -.
DR   Ensembl; ENST00000610462; ENSP00000478923; ENSG00000114646.
DR   GeneID; 10675; -.
DR   UCSC; uc021wxh.2; human.
DR   CTD; 10675; -.
DR   EuPathDB; HostDB:ENSG00000114646.9; -.
DR   HGNC; HGNC:2467; CSPG5.
DR   OpenTargets; ENSG00000114646; -.
DR   eggNOG; ENOG410IJTR; Eukaryota.
DR   eggNOG; ENOG410YF9F; LUCA.
DR   GeneTree; ENSGT00440000034270; -.
DR   OrthoDB; 433725at2759; -.
DR   ChiTaRS; CSPG5; human.
DR   GenomeRNAi; 10675; -.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000114646; Expressed in 147 organ(s), highest expression level in endothelial cell.
DR   ExpressionAtlas; A0A087WUT8; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR010555; CSPG5_S_attach_dom.
DR   Pfam; PF06566; Chon_Sulph_att; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:A0A087WUT8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     29       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        30    477       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001831922.
FT   TRANSMEM    419    444       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       33    277       Chon_Sulph_att.
FT                                {ECO:0000259|Pfam:PF06566}.
SQ   SEQUENCE   477 AA;  50190 MW;  A9FCB4B592FBDBB2 CRC64;
     MGRAGGGGPG RGPPPLLLFL GAALVLASGA VPAREAGSAV EAEELVKGSP AWEPPANDTR
     EEAGPPAAGE DEASWTAPGG ELAGPEEVLQ ESAAVTGTAW LEADSPGLGG VTAEAGSGDA
     QALPATLQAP HEVLGQSIMP PAIPEATEAS GPPSPTPGDK LSPASELPKE SPLEVWLNLG
     GSTPDPQGPE LTYPFQGTLE PQPASDIIDI DYFEGLDGEG RGADLGSFPG SPGTSENHPD
     TEGETPSWSL LDLYDDFTPF DESDFYPTTS FYDDLDEEEE EEEDDKDAVG GGDLEDENEL
     LVPTGKPGLG PGTGQPTSRW HAVPPQHTLG SVPGSSIALR PRPGEPGRDL ASSENGTECR
     SGFVRHNGSC RSVCDLFPSY CHNGGQCYLV ENIGAFCRCN TQDYIWHKGM RCESIITDFQ
     VMCVAVGSAA LVLLLLFMMT VFFAKKLYLL KTENTKLRRT KMILVLPTKS RRFSSPA
//