ID   A0A087WUR8_HUMAN        Unreviewed;       416 AA.
AC   A0A087WUR8;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   16-JAN-2019, entry version 30.
DE   SubName: Full=Inactive serine protease PAMR1 {ECO:0000313|Ensembl:ENSP00000478867};
GN   Name=PAMR1 {ECO:0000313|Ensembl:ENSP00000478867};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000478867, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000478867, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000478867}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2014) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR   EMBL; AC090625; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL354921; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF510369; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; A0A087WUR8; -.
DR   jPOST; A0A087WUR8; -.
DR   PeptideAtlas; A0A087WUR8; -.
DR   Ensembl; ENST00000611014; ENSP00000478867; ENSG00000149090.
DR   UCSC; uc058ajx.1; human.
DR   EuPathDB; HostDB:ENSG00000149090.11; -.
DR   HGNC; HGNC:24554; PAMR1.
DR   OpenTargets; ENSG00000149090; -.
DR   GeneTree; ENSGT00940000154234; -.
DR   ChiTaRS; PAMR1; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000149090; Expressed in 199 organ(s), highest expression level in decidua.
DR   ExpressionAtlas; A0A087WUR8; baseline and differential.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   CDD; cd00033; CCP; 1.
DR   CDD; cd00190; Tryp_SPc; 1.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR001314; Peptidase_S1A.
DR   InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR   InterPro; IPR001254; Trypsin_dom.
DR   Pfam; PF00084; Sushi; 1.
DR   Pfam; PF00089; Trypsin; 1.
DR   PRINTS; PR00722; CHYMOTRYPSIN.
DR   SMART; SM00020; Tryp_SPc; 1.
DR   SUPFAM; SSF50494; SSF50494; 1.
DR   PROSITE; PS50923; SUSHI; 1.
DR   PROSITE; PS50240; TRYPSIN_DOM; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS00938116};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A087WUR8,
KW   ECO:0000213|PeptideAtlas:A0A087WUR8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    416       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001831919.
FT   DOMAIN       83    140       Sushi. {ECO:0000259|PROSITE:PS50923}.
FT   DOMAIN      141    416       Peptidase S1.
FT                                {ECO:0000259|PROSITE:PS50240}.
SQ   SEQUENCE   416 AA;  46547 MW;  0F6A1FE0FADEA6BC CRC64;
     MLKLAPWCLS FVTTPMFLVA MRKELASRME WSGKQPICIK ACREPKISDL VRRRVLPMQV
     QSRETPLHQL YSAAFSKQKL QSAPTKKPAL PFGDLPMGYQ HLHTQLQYEC ISPFYRRLGS
     SRRTCLRTGK WSGRAPSCIP ICGKIENITA PKTQGLRWPW QAAIYRRTSG VHDGSLHKGA
     WFLVCSGALV NERTVVVAAH CVTDLGKVTM IKTADLKVVL GKFYRDDDRD EKTIQSLQIS
     AIILHPNYDP ILLDADIAIL KLLDKARIST RVQPICLAAS RDLSTSFQES HITVAGWNVL
     ADVRSPGFKN DTLRSGVVSV VDSLLCEEQH EDHGIPVSVT DNMFCASWEP TAPSDICTAE
     TGGIAAVSFP GRASPEPRWH LMGLVSWSYD KTCSHRLSTA FTKVLPFKDW IERNMK
//