ID   A0A087WSX8_HUMAN        Unreviewed;       651 AA.
AC   A0A087WSX8;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   16-JAN-2019, entry version 34.
DE   SubName: Full=Leukocyte immunoglobulin-like receptor subfamily B member 1 {ECO:0000313|Ensembl:ENSP00000379618};
GN   Name=LILRB1 {ECO:0000313|Ensembl:ENSP00000379618};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000379618, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000379618, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000379618}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2014) to UniProtKB.
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DR   EMBL; AC245036; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001075107.2; NM_001081638.3.
DR   UniGene; Hs.667388; -.
DR   ProteinModelPortal; A0A087WSX8; -.
DR   jPOST; A0A087WSX8; -.
DR   PeptideAtlas; A0A087WSX8; -.
DR   PRIDE; A0A087WSX8; -.
DR   Ensembl; ENST00000396327; ENSP00000379618; ENSG00000104972.
DR   GeneID; 10859; -.
DR   UCSC; uc032ieg.2; human.
DR   CTD; 10859; -.
DR   EuPathDB; HostDB:ENSG00000104972.15; -.
DR   HGNC; HGNC:6605; LILRB1.
DR   OpenTargets; ENSG00000104972; -.
DR   eggNOG; ENOG410IKJD; Eukaryota.
DR   eggNOG; ENOG41116BR; LUCA.
DR   GeneTree; ENSGT00940000153160; -.
DR   OrthoDB; 1000446at2759; -.
DR   ChiTaRS; LILRB1; human.
DR   GenomeRNAi; 10859; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000104972; Expressed in 179 organ(s), highest expression level in spleen.
DR   ExpressionAtlas; A0A087WSX8; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 4.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR013151; Immunoglobulin.
DR   Pfam; PF00047; ig; 1.
DR   Pfam; PF13895; Ig_2; 1.
DR   SMART; SM00409; IG; 4.
DR   SMART; SM00408; IGc2; 3.
DR   SUPFAM; SSF48726; SSF48726; 4.
DR   PROSITE; PS50835; IG_LIKE; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Immunoglobulin domain {ECO:0000256|SAAS:SAAS00442402};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A087WSX8,
KW   ECO:0000213|PeptideAtlas:A0A087WSX8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     23       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        24    651       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001831881.
FT   TRANSMEM    460    484       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       27    115       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      313    409       Ig-like. {ECO:0000259|PROSITE:PS50835}.
SQ   SEQUENCE   651 AA;  70918 MW;  CDDE9E5930482B56 CRC64;
     MTPILTVLIC LGLSLGPRTH VQAGHLPKPT LWAEPGSVIT QGSPVTLRCQ GGQETQEYRL
     YREKKTAPWI TRIPQELVKK GQFPIPSITW EHTGRYRCYY GSDTAGRSES SDPLELVVTG
     AYIKPTLSAQ PSPVVNSGGN VTLQCDSQVA FDGFILCKEG EDEHPQCLNS QPHARGSSRA
     IFSVGPVSPS RRWWYRCYAY DSNSPYEWSL PSDLLELLVL GVSKKPSLSV QPGPIVAPEE
     TLTLQCGSDA GYNRFVLYKD GERDFLQLAG AQPQAGLSQA NFTLGPVSRS YGGQYRCYGA
     HNLSSEWSAP SDPLDILIAG QFYDRVSLSV QPGPTVASGE NVTLLCQSQG WMQTFLLTKE
     GAADDPWRLR STYQSQKYQA EFPMGPVTSA HAGTYRCYGS QSSKPYLLTH PSDPLELVVS
     GPSGGPSSPT TGPTSTSAGP EDQPLTPTGS DPQSGLGRHL GVVIGILVAV ILLLLLLLLL
     FLILRHRRQG KHWTSTQRKA DFQHPAGAVG PEPTDRGLQW RSSPAADAQE ENLYAAVKHT
     QPEDGVEMDT RSPHDEDPQA VTYAEVKHSR PRREMASPPS PLSGEFLDTK DRQAEEDRQM
     DTEAAASEAP QDVTYAQLHS LTLRREATEP PPSQEGPSPA VPSIYATLAI H
//