ID   A0A075B7F0_HUMAN        Unreviewed;       116 AA.
AC   A0A075B7F0;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   13-FEB-2019, entry version 27.
DE   SubName: Full=Immunoglobulin heavy variable 3/OR16-10 (non-functional) {ECO:0000313|Ensembl:ENSP00000474941};
DE   Flags: Fragment;
GN   Name=IGHV3OR16-10 {ECO:0000313|Ensembl:ENSP00000474941};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000474941, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000474941, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X.,
RA   Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A.,
RA   Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.,
RA   Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L.,
RA   Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A.,
RA   Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D.,
RA   Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J.,
RA   Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I.,
RA   Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W.,
RA   Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A.,
RA   Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S.,
RA   Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L.,
RA   Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A.,
RA   Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L.,
RA   Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N.,
RA   Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M.,
RA   Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L.,
RA   Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D.,
RA   Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P.,
RA   Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M.,
RA   Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000474941}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2014) to UniProtKB.
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DR   EMBL; AC142086; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; A0A075B7F0; -.
DR   SMR; A0A075B7F0; -.
DR   STRING; 9606.ENSP00000396505; -.
DR   BioMuta; IGHV3OR16-10; -.
DR   jPOST; A0A075B7F0; -.
DR   PaxDb; A0A075B7F0; -.
DR   Ensembl; ENST00000425181; ENSP00000474941; ENSG00000233732.
DR   UCSC; uc059tqx.1; human.
DR   EuPathDB; HostDB:ENSG00000233732.5; -.
DR   GeneCards; IGHV3OR16-10; -.
DR   HGNC; HGNC:5634; IGHV3OR16-10.
DR   eggNOG; ENOG410KC4R; Eukaryota.
DR   eggNOG; ENOG410YQJV; LUCA.
DR   GeneTree; ENSGT00940000154310; -.
DR   OMA; SATYCCA; -.
DR   ChiTaRS; IGHV3OR16-10; human.
DR   Proteomes; UP000005640; Chromosome 16.
DR   Bgee; ENSG00000233732; Expressed in 42 organ(s), highest expression level in adrenal gland.
DR   GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0042571; C:immunoglobulin complex, circulating; IBA:GO_Central.
DR   GO; GO:0003823; F:antigen binding; IBA:GO_Central.
DR   GO; GO:0034987; F:immunoglobulin receptor binding; IBA:GO_Central.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IBA:GO_Central.
DR   GO; GO:0006958; P:complement activation, classical pathway; IBA:GO_Central.
DR   GO; GO:0042742; P:defense response to bacterium; IBA:GO_Central.
DR   GO; GO:0045087; P:innate immune response; IBA:GO_Central.
DR   GO; GO:0006911; P:phagocytosis, engulfment; IBA:GO_Central.
DR   GO; GO:0006910; P:phagocytosis, recognition; IBA:GO_Central.
DR   GO; GO:0050871; P:positive regulation of B cell activation; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:A0A075B7F0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    116       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001705238.
FT   DOMAIN       34    116       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   NON_TER     116    116       {ECO:0000313|Ensembl:ENSP00000474941}.
SQ   SEQUENCE   116 AA;  12579 MW;  86FCE373C1603792 CRC64;
     MEFVLSWVFL VAILKGVQCE VQLVQSGGGL VHPGGSLRLS CAGSGFTFSS YAMHWVRQAP
     GKGLEWVSAI GTGGGTYYAD SVKGRFTISR DNAKNSLYLQ MNSLRAEDMA VYYCAR
//