ID   A0A075B731_HUMAN        Unreviewed;       114 AA.
AC   A0A075B731;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 2.
DT   13-FEB-2019, entry version 21.
DE   SubName: Full=Modulator of smoothened protein {ECO:0000313|Ensembl:ENSP00000456262};
GN   Name=MOSMO {ECO:0000313|Ensembl:ENSP00000456262};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000456262, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000456262, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X.,
RA   Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A.,
RA   Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.,
RA   Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L.,
RA   Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A.,
RA   Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D.,
RA   Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J.,
RA   Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I.,
RA   Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W.,
RA   Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A.,
RA   Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S.,
RA   Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L.,
RA   Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A.,
RA   Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L.,
RA   Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N.,
RA   Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M.,
RA   Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L.,
RA   Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D.,
RA   Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P.,
RA   Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M.,
RA   Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000456262}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2014) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC009019; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC092119; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877596; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; A0A075B731; -.
DR   Ensembl; ENST00000569656; ENSP00000456262; ENSG00000185716.
DR   UCSC; uc059rxr.1; human.
DR   EuPathDB; HostDB:ENSG00000185716.11; -.
DR   HGNC; HGNC:27087; MOSMO.
DR   OpenTargets; ENSG00000185716; -.
DR   eggNOG; ENOG410IJ25; Eukaryota.
DR   eggNOG; ENOG410Z2QM; LUCA.
DR   GeneTree; ENSGT00390000018266; -.
DR   PhylomeDB; A0A075B731; -.
DR   ChiTaRS; C16orf52; human.
DR   Proteomes; UP000005640; Chromosome 16.
DR   Bgee; ENSG00000185716; Expressed in 208 organ(s), highest expression level in primary visual cortex.
DR   ExpressionAtlas; A0A075B731; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR037663; Mosmo.
DR   PANTHER; PTHR31186; PTHR31186; 1.
DR   Pfam; PF18800; Atthog; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     26       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        27    114       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001705212.
FT   TRANSMEM     68     88       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   114 AA;  12543 MW;  42265CDAA0FF533C CRC64;
     MDKLTIISGC LFLAADIFAI ASIANPDWIN TGESAGALTV GLVRQCQTIH GRDRTCIPPR
     LPPEWVTTLF FIIMGIISLT VTCGLLVASH WRREATKYAR WIAFTGKCVH SSHT
//