biomarker_id biomarker assessed_biomarker_entity assessed_biomarker_entity_id assessed_entity_type condition condition_id exposure_agent exposure_agent_id best_biomarker_role specimen specimen_id loinc_code evidence_source evidence tag vocab_pattern biomarker_controlled_vocab component_group flags BMKB151581-1 Presence of Polystyrene microplastics Polystyrene CHEBI:53276 metabolite Polystyrene CHEBI:53276 monitoring placenta UBERON:000198 PubMed:38366932 'Py-GC-MS revealed that microplastics were present in all participants’ placentae, with concentrations ranging widely from 6.5 to 685mg NMPs per gram of placental tissue, averaging 126.8±147.5mg/g (mean±SD)' assessed_biomarker_entity;assessed_biomarker_entity_id;assessed_entity_type;best_biomarker_role;biomarker;exposure_agent;exposure_agent_id;specimen;specimen_id;evidence_source;evidence Presence of Polystyrene microplastics [biomarker_term_in_review] 1 not_mapped BMKB151581-1 Presence of Polystyrene microplastics Polystyrene CHEBI:53276 metabolite Polystyrene CHEBI:53276 monitoring kidney UBERON:0002113 PubMed:33956507 'PS-MPs were evaluated in human kidney proximal tubular epithelial cells (HK-2 cells) and male C57BL/6 mice' assessed_biomarker_entity;assessed_biomarker_entity_id;assessed_entity_type;best_biomarker_role;biomarker;exposure_agent;exposure_agent_id;specimen;specimen_id;evidence_source;evidence Presence of Polystyrene microplastics [biomarker_term_in_review] 2 not_mapped BMKB151581-1 Presence of Polystyrene microplastics Polystyrene CHEBI:53276 metabolite Polystyrene CHEBI:53276 monitoring blood UBERON:0000178 PubMed:35367073 'Polyethylene terephthalate, polyethylene and polymers of styrene (a sum parameter of polystyrene, expanded polystyrene, acetonitrile butadiene styrene etc.) were the most widely encountered' assessed_biomarker_entity;assessed_biomarker_entity_id;assessed_entity_type;best_biomarker_role;biomarker;exposure_agent;exposure_agent_id;specimen;specimen_id;evidence_source;evidence Presence of Polystyrene microplastics [biomarker_term_in_review] 3 not_mapped BMKB151582-1 Presence of Polyethylene microplastics Polyethylene CHEBI:53227 metabolite Polyethylene CHEBI:53227 monitoring placenta UBERON:000198 PubMed:38366932 'Py-GC-MS revealed that microplastics were present in all participants’ placentae, with concentrations ranging widely from 6.5 to 685mg NMPs per gram of placental tissue, averaging 126.8±147.5mg/g (mean±SD)' assessed_biomarker_entity;assessed_biomarker_entity_id;assessed_entity_type;best_biomarker_role;biomarker;exposure_agent;exposure_agent_id;specimen;specimen_id;evidence_source;evidence Presence of Polyethylene microplastics [biomarker_term_in_review] 4 not_mapped BMKB151582-1 Presence of Polyethylene microplastics Polyethylene CHEBI:53227 metabolite Polyethylene CHEBI:53227 monitoring blood UBERON:0000178 PubMed:35367073 'Polyethylene terephthalate, polyethylene and polymers of styrene (a sum parameter of polystyrene, expanded polystyrene, acetonitrile butadiene styrene etc.) were the most widely encountered' assessed_biomarker_entity;assessed_biomarker_entity_id;assessed_entity_type;best_biomarker_role;biomarker;exposure_agent;exposure_agent_id;specimen;specimen_id;evidence_source;evidence Presence of Polyethylene microplastics [biomarker_term_in_review] 5 not_mapped BMKB151597-1 Presence of Polypropylene microplastics Polypropylene CHEBI:53550 metabolite Polypropylene CHEBI:53550 monitoring placenta UBERON:000198 PubMed:38366932 'Py-GC-MS revealed that microplastics were present in all participants’ placentae, with concentrations ranging widely from 6.5 to 685mg NMPs per gram of placental tissue, averaging 126.8±147.5mg/g (mean±SD)' assessed_biomarker_entity;assessed_biomarker_entity_id;assessed_entity_type;best_biomarker_role;biomarker;exposure_agent;exposure_agent_id;specimen;specimen_id;evidence_source;evidence Presence of Polypropylene microplastics [biomarker_term_in_review] 6 not_mapped BMKB151597-1 Presence of Polypropylene microplastics Polypropylene CHEBI:53550 metabolite Polypropylene CHEBI:53550 monitoring blood UBERON:0000178 PubMed:35367073 'Polyethylene terephthalate, polyethylene and polymers of styrene (a sum parameter of polystyrene, expanded polystyrene, acetonitrile butadiene styrene etc.) were the most widely encountered' assessed_biomarker_entity;assessed_biomarker_entity_id;assessed_entity_type;best_biomarker_role;biomarker;exposure_agent;exposure_agent_id;specimen;specimen_id;evidence_source;evidence Presence of Polypropylene microplastics [biomarker_term_in_review] 7 not_mapped BMKB151549-1 Presence of Polyethylene terephthalate microplastics Polyethylene terephthalate CHEBI:53259 metabolite Polyethylene terephthalate CHEBI:53259 monitoring blood UBERON:0000178 PubMed:35367073 'Polyethylene terephthalate, polyethylene and polymers of styrene (a sum parameter of polystyrene, expanded polystyrene, acetonitrile butadiene styrene etc.) were the most widely encountered' assessed_biomarker_entity;assessed_biomarker_entity_id;assessed_entity_type;best_biomarker_role;biomarker;exposure_agent;exposure_agent_id;specimen;specimen_id;evidence_source;evidence Presence of Polyethylene terephthalate microplastics [biomarker_term_in_review] 8 not_mapped BMKB151602-1 Presence of Polyvinyl chloride microplastics Polyvinyl chloride CHEBI:53243 metabolite Polyvinyl chloride CHEBI:53243 monitoring placenta UBERON:000198 PubMed:38366932 'Py-GC-MS revealed that microplastics were present in all participants’ placentae, with concentrations ranging widely from 6.5 to 685mg NMPs per gram of placental tissue, averaging 126.8±147.5mg/g (mean±SD)' assessed_biomarker_entity;assessed_biomarker_entity_id;assessed_entity_type;best_biomarker_role;biomarker;exposure_agent;exposure_agent_id;specimen;specimen_id;evidence_source;evidence Presence of Polyvinyl chloride microplastics [biomarker_term_in_review] 9 not_mapped BMKB062258-1 Increased IL6 level Interleukin-6 UPKB:P05231 protein microplastics meSHID:D000080545 safety blood UBERON:0000178 PubMed:39164741 'A significant relationship was observed between increased microplastic levels and enhanced IL-6...' assessed_biomarker_entity;assessed_biomarker_entity_id;assessed_entity_type;best_biomarker_role;biomarker;exposure_agent;exposure_agent_id;specimen;specimen_id;evidence_source;evidence change_type:increased;aspect_type:level Increased level of protein IL6/UPKB:P05231 10 BMKB116102-1 Increased TNF level Tumor necrosis factor UPKB:P01375 protein microplastics meSHID:D000080546 safety blood UBERON:0000178 PubMed:39946929 'Serum levels of tumor necrosis factor-α (TNF-α)... were elevated compared with those in the control group (p < 0.05)' assessed_biomarker_entity;assessed_biomarker_entity_id;assessed_entity_type;best_biomarker_role;biomarker;exposure_agent;exposure_agent_id;specimen;specimen_id;evidence_source;evidence change_type:increased;aspect_type:level Increased level of protein TNF/UPKB:P01375 11 BMKB116102-1 Increased TNF level Tumor necrosis factor UPKB:P01375 protein microplastics meSHID:D000080546 safety blood UBERON:0000178 PubMed:39164741 'We examined correlations between the levels of a panel of inflammatory cytokines... TNF-α' assessed_biomarker_entity;assessed_biomarker_entity_id;assessed_entity_type;best_biomarker_role;biomarker;exposure_agent;exposure_agent_id;specimen;specimen_id;evidence_source;evidence change_type:increased;aspect_type:level Increased level of protein TNF/UPKB:P01375 12 BMKB098020-1 Increased CRP level C-reactive protein UPKB:P02741 protein microplastics meSHID:D000080547 safety blood UBERON:0000178 PubMed:39638849 'A high MP load in the blood… was significantly correlated with increased… C-reactive protein…' assessed_biomarker_entity;assessed_biomarker_entity_id;assessed_entity_type;best_biomarker_role;biomarker;exposure_agent;exposure_agent_id;specimen;specimen_id;evidence_source;evidence change_type:increased;aspect_type:level Increased level of protein CRP/UPKB:P02741 13 BMKB098020-1 Increased CRP level C-reactive protein UPKB:P02741 protein microplastics meSHID:D000080547 safety blood UBERON:0000178 PubMed:39164741 'We examined correlations between the levels of a panel of inflammatory cytokines...and the levels of high-sensitivity C-reactive protein (hs-CRP) in relation to the concentration of various MPs.' assessed_biomarker_entity;assessed_biomarker_entity_id;assessed_entity_type;best_biomarker_role;biomarker;exposure_agent;exposure_agent_id;specimen;specimen_id;evidence_source;evidence change_type:increased;aspect_type:level Increased level of protein CRP/UPKB:P02741 14 BMKB151588-1 Decreased thyroxine Thyroxine hormone PCCID:5819 protein microplastics meSHID:D000080548 safety blood UBERON:0000178 PubMed:41032983 'Adjusted MLR models confirmed that individual microplastic types, including PVC, PP, and PBS, were significantly associated with reductions in T4 levels (β = -1.40, -0.74, and -0.85, respectively) and TSH levels' assessed_biomarker_entity;assessed_biomarker_entity_id;assessed_entity_type;best_biomarker_role;biomarker;exposure_agent;exposure_agent_id;specimen;specimen_id;evidence_source;evidence change_type:decreased;aspect_type:level Decreased level of protein thyroxine hormone/PCCID:5819 15 BMKB151591-1 Decreased thyroid stimulating hormone Thyroid stimulating hormone PCSID:485716527 protein microplastics meSHID:D000080549 safety blood UBERON:0000178 PubMed:41032983 'Adjusted MLR models confirmed that individual microplastic types, including PVC, PP, and PBS, were significantly associated with reductions in T4 levels (β = -1.40, -0.74, and -0.85, respectively) and TSH levels' assessed_biomarker_entity;assessed_biomarker_entity_id;assessed_entity_type;best_biomarker_role;biomarker;exposure_agent;exposure_agent_id;specimen;specimen_id;evidence_source;evidence Decreased thyroid stimulating hormone [biomarker_term_in_review] 16 not_mapped