{
    "uniprot_canonical_ac": "A0A286ZKE4-1",
    "uniprot_id": [
        {
            "id": "A0A286ZKE4_PIG",
            "url": "https://www.uniprot.org/uniprot/A0A286ZKE4_PIG",
            "type": "external"
        }
    ],
    "mass": 47630.0,
    "length": 425,
    "protein_name": "Polyribonucleotide 5'-hydroxyl-kinase Clp1",
    "gene_name": "CLP1",
    "organism": "Pig",
    "refseq_name": "polyribonucleotide 5'-hydroxyl-kinase Clp1",
    "refseq_ac": [
        {
            "id": "XP_003122764",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122764",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "CLP1",
    "gene_names_refseq": "CLP1",
    "protein_names_uniprotkb": "Polyribonucleotide 5'-hydroxyl-kinase Clp1; 2.7.1.78; Polyadenylation factor Clp1; Polynucleotide kinase Clp1; Pre-mRNA cleavage complex II protein Clp1",
    "protein_names_refseq": "polyribonucleotide 5'-hydroxyl-kinase Clp1",
    "tax_id": 9823,
    "disease": "",
    "pathway": " (ssc:100520541);  (R-SSC-72187);  (R-SSC-72203);  (R-SSC-73856);  (R-SSC-77595)",
    "pathway_count": 5,
    "publication_count": 1,
    "publication_id_list": "30723633",
    "function": "Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing., [UniProtKB, HAMAP]",
    "predicted_glycosites": 2,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 2,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 2,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 0,
    "glyco_site_count": 2,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [],
    "go_molecular_function": "GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity;GO:0051736 ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity;GO:0005524 ATP binding;GO:0051731 polynucleotide 5'-hydroxyl-kinase activity",
    "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005849 mRNA cleavage factor complex;GO:0000214 tRNA-intron endonuclease complex",
    "go_biological_process": "GO:0070922 RISC complex assembly;GO:0021695 cerebellar cortex development;GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation;GO:0031124 mRNA 3'-end processing;GO:0098795 global gene silencing by mRNA cleavage",
    "synthesized_glycan_count": 0,
    "record_id": "A0A286ZKE4-1",
    "record_type": "protein",
    "filter_code": "0000000.0000101.100000.0000000000010000.00010.001"
}