{
    "uniprot_canonical_ac": "A0A286ZI97-1",
    "uniprot_id": [
        {
            "id": "A0A286ZI97_PIG",
            "url": "https://www.uniprot.org/uniprot/A0A286ZI97_PIG",
            "type": "external"
        }
    ],
    "mass": 24187.0,
    "length": 222,
    "protein_name": "Peptidoglycan-recognition protein",
    "gene_name": "PGLYRP1",
    "organism": "Pig",
    "refseq_name": "",
    "refseq_ac": [],
    "gene_names_uniprotkb": "PGLYRP1",
    "gene_names_refseq": "",
    "protein_names_uniprotkb": "Peptidoglycan-recognition protein",
    "protein_names_refseq": "",
    "tax_id": 9823,
    "disease": "",
    "pathway": " (R-SSC-6798695);  (R-SSC-6803157)",
    "pathway_count": 2,
    "publication_count": 0,
    "publication_id_list": "",
    "function": "Innate immunity protein that plays several important functions in antimicrobial and antitumor defense systems. Acts as a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria and thus provides bactericidal activity. Forms an equimolar complex with heat shock protein HSPA1A and induces programmed cell death through apoptosis and necroptosis in tumor cell lines by activating the TNFR1 receptor on the target cell membrane. In addition, acts in complex with the Ca(2+)-binding protein S100A4 as a chemoattractant able to induce lymphocyte movement. Mechanistically, this complex acts as a ligand of the chemotactic receptors CCR5 and CXCR3 which are present on the cells of the immune system. Promotes also the activation of lymphocytes that become able to kill virus-infected cells as well as tumor cells by modulating the spectrum of their target-cell specificity. Induction of cytotoxicity on monocyte surface requires interaction with TREM1 receptor., [UniProtKB, UniProtKB]",
    "predicted_glycosites": 1,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 1,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 1,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 0,
    "glyco_site_count": 1,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [],
    "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0042834 peptidoglycan binding;GO:0008745 N-acetylmuramoyl-L-alanine amidase activity;GO:0008270 zinc ion binding;GO:0048018 receptor ligand activity",
    "go_cellular_component": "GO:0005615 extracellular space",
    "go_biological_process": "GO:0032827 negative regulation of natural killer cell differentiation involved in immune response;GO:0006955 immune response;GO:0045087 innate immune response;GO:0050830 defense response to Gram-positive bacterium;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide",
    "synthesized_glycan_count": 0,
    "record_id": "A0A286ZI97-1",
    "record_type": "protein",
    "filter_code": "0000000.0000001.100000.0000000000010000.00010.001"
}