{
    "uniprot_canonical_ac": "A0A1Z2R986-1",
    "uniprot_id": [
        {
            "id": "EGLN_DANRE",
            "url": "https://www.uniprot.org/uniprot/EGLN_DANRE",
            "type": "external"
        }
    ],
    "mass": 61300.0,
    "length": 559,
    "protein_name": "Endoglin",
    "gene_name": "eng",
    "organism": "Zebrafish",
    "refseq_name": "endoglin isoform X1",
    "refseq_ac": [
        {
            "id": "XP_021332381",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332381",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "eng",
    "gene_names_refseq": "eng",
    "protein_names_uniprotkb": "Endoglin",
    "protein_names_refseq": "endoglin isoform X1",
    "tax_id": 7955,
    "disease": "renal fibrosis (Disease Ontology:DOID:0050855); arteriovenous malformations of the brain (Disease Ontology:DOID:0060688); prostate cancer (Disease Ontology:DOID:10283); lymphoid leukemia (Disease Ontology:DOID:1037); pre-eclampsia (Disease Ontology:DOID:10591); hypertension (Disease Ontology:DOID:10763); intracranial aneurysm (Disease Ontology:DOID:10941); arteriovenous malformation (Disease Ontology:DOID:11294); secondary hyperparathyroidism (Disease Ontology:DOID:12466); hereditary hemorrhagic telangiectasia (Disease Ontology:DOID:1270); cholestasis (Disease Ontology:DOID:13580); breast cancer (Disease Ontology:DOID:1612); coronary artery disease (Disease Ontology:DOID:3393); clear cell renal cell carcinoma (Disease Ontology:DOID:4467); congestive heart failure (Disease Ontology:DOID:6000); hepatocellular carcinoma (Disease Ontology:DOID:684); diabetic retinopathy (Disease Ontology:DOID:8947); multiple myeloma (Disease Ontology:DOID:9538); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)",
    "pathway": " (dre:101883074)",
    "pathway_count": 1,
    "publication_count": 2,
    "publication_id_list": "23594743;28530658",
    "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_000002035.6-RS_2024_08 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 08/15/2024 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 127 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007116.7) and transcript sequence (GDQQ01010520.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Important for endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis., [UniProtKB, PubMed]",
    "predicted_glycosites": 8,
    "predicted_n_glycosites": 7,
    "predicted_o_glycosites": 1,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 7,
    "total_o_glycosites": 1,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 19,
    "glyco_site_count": 8,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [],
    "go_molecular_function": "GO:0005024 transforming growth factor beta receptor activity;GO:0005114 type II transforming growth factor beta receptor binding;GO:0005539 glycosaminoglycan binding",
    "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane",
    "go_biological_process": "GO:0017015 regulation of transforming growth factor beta receptor signaling pathway;GO:0001525 angiogenesis;GO:0007507 heart development;GO:0016477 cell migration;GO:0007179 transforming growth factor beta receptor signaling pathway",
    "synthesized_glycan_count": 0,
    "record_id": "A0A1Z2R986-1",
    "record_type": "protein",
    "filter_code": "0000000.0000111.100000.0000000000000001.00110.001"
}