{
    "uniprot_canonical_ac": "A0A1L4FML6-1",
    "uniprot_id": [
        {
            "id": "A0A1L4FML6_CHICK",
            "url": "https://www.uniprot.org/uniprot/A0A1L4FML6_CHICK",
            "type": "external"
        }
    ],
    "mass": 122295.0,
    "length": 1059,
    "protein_name": "Toll-like receptor 7",
    "gene_name": "TLR7",
    "organism": "Chicken",
    "refseq_name": "toll-like receptor 7",
    "refseq_ac": [
        {
            "id": "NP_001011688",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011688",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "TLR7",
    "gene_names_refseq": "TLR7",
    "protein_names_uniprotkb": "Toll-like receptor 7",
    "protein_names_refseq": "toll-like receptor 7-long; toll-like receptor 7",
    "tax_id": 9031,
    "disease": "",
    "pathway": " (gga:418638)",
    "pathway_count": 1,
    "publication_count": 3,
    "publication_id_list": "30514372;31973574;32524263",
    "function": "##Evidence-Data-START## Transcript exon combination :: AJ720504.1, KM486607.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000024.1, AJ740367.1, KM486601.1, KM486600.1 and AJ720504.1. On Nov 24, 2021 this sequence version replaced NP_001011688.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Antiviral response elicited against avian influenza virus infection following activation of TLR7 signaling pathway is attributable to interleukin IL-1beta production. Publication Status: Online-Only, [RefSeq, PubMed]; Infectious bronchitis virus inhibits activation of the TLR7 pathway, but not the TLR3 pathway., [RefSeq, PubMed]; Results showed that activation of TLR7 is associated with anorexia, hypoactivity, hypothermia, disturbance of feed passage in the digestive tract and the response to stress in chicks, [RefSeq, PubMed]",
    "predicted_glycosites": 1,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 1,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 1,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 0,
    "glyco_site_count": 1,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [],
    "go_molecular_function": "GO:0003725 double-stranded RNA binding;GO:0003727 single-stranded RNA binding;GO:0035197 siRNA binding;GO:0038187 pattern recognition receptor activity",
    "go_cellular_component": "GO:0005768 endosome;GO:0005764 lysosome;GO:0005789 endoplasmic reticulum membrane;GO:0045335 phagocytic vesicle;GO:0005886 plasma membrane",
    "go_biological_process": "GO:0006954 inflammatory response;GO:0007165 signal transduction;GO:0045087 innate immune response;GO:0002218 activation of innate immune response;GO:1902533 positive regulation of intracellular signal transduction",
    "synthesized_glycan_count": 0,
    "record_id": "A0A1L4FML6-1",
    "record_type": "protein",
    "filter_code": "0000000.0000101.010000.0001000000000000.00010.001"
}
