{
    "uniprot_canonical_ac": "A0A1D5PJ69-1",
    "uniprot_id": [
        {
            "id": "A0A1D5PJ69_CHICK",
            "url": "https://www.uniprot.org/uniprot/A0A1D5PJ69_CHICK",
            "type": "external"
        }
    ],
    "mass": 100923.0,
    "length": 902,
    "protein_name": "Glutamate receptor",
    "gene_name": "GRIA4",
    "organism": "Chicken",
    "refseq_name": "glutamate receptor 4 isoform 2 precursor",
    "refseq_ac": [
        {
            "id": "NP_990545",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990545",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "GRIA4",
    "gene_names_refseq": "GRIA4; GluR4; GLUR4/D; GluR4c; GluR4d; GluR4s",
    "protein_names_uniprotkb": "Glutamate receptor",
    "protein_names_refseq": "AMPA receptor GluR4/D; glutamate receptor subunit GluR4; glutamate receptor, ionotrophic, AMPA 4; glutamate receptor, ionotropic, AMPA 4; glutamate receptor 4; glutamate receptor 4 isoform 2 precursor",
    "tax_id": 9031,
    "disease": "",
    "pathway": "",
    "pathway_count": 0,
    "publication_count": 2,
    "publication_id_list": "15255946;17233759",
    "function": "##Evidence-Data-START## Transcript exon combination :: X89507.1, SRR13267649.254949.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## undergoes RNA editing       :: PMID: 10688364 ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000027.1. On Dec 3, 2021 this sequence version replaced NP_990545.1. Transcript Variant: This variant (2) uses an alternate internal coding exon compared to transcript variant 1, and encodes an isoform (2, also known as flop isoform) that is the same length, but with a few amino acid differences compared to isoform 1. RNA editing (AGA->GGA) changes Arg765Gly., [RefSeq]; Our data show that GluR4 phosphorylation at Ser842 by PKA, and its recruitment to the plasma membrane upon phosphorylation, is regulated by metabotropic receptors, [RefSeq, PubMed]; Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; The present findings show that the interaction between PKCgamma and GluR4 is specifically required to assure PKC-driven phosphorylation and surface membrane expression of GluR4., [RefSeq, PubMed]",
    "predicted_glycosites": 0,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 0,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 0,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 0,
    "glyco_site_count": 0,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [],
    "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0038023 signaling receptor activity;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0004971 AMPA glutamate receptor activity;GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential",
    "go_cellular_component": "GO:0045211 postsynaptic membrane;GO:0005886 plasma membrane;GO:0043197 dendritic spine;GO:0032281 AMPA glutamate receptor complex;GO:0098839 postsynaptic density membrane",
    "go_biological_process": "GO:0035249 synaptic transmission, glutamatergic;GO:0050804 modulation of chemical synaptic transmission;GO:0034392 negative regulation of smooth muscle cell apoptotic process",
    "synthesized_glycan_count": 0,
    "record_id": "A0A1D5PJ69-1",
    "record_type": "protein",
    "filter_code": "0000000.0000100.010000.0001000000000000.00000.000"
}