{
    "uniprot_canonical_ac": "A0A1D5P4G9-1",
    "uniprot_id": [
        {
            "id": "A0A1D5P4G9_CHICK",
            "url": "https://www.uniprot.org/uniprot/A0A1D5P4G9_CHICK",
            "type": "external"
        }
    ],
    "mass": 23040.0,
    "length": 219,
    "protein_name": "Achaete-scute family bHLH transcription factor 1",
    "gene_name": "ASCL1",
    "organism": "Chicken",
    "refseq_name": "achaete-scute homolog 1",
    "refseq_ac": [
        {
            "id": "NP_989743",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989743",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "ASCL1",
    "gene_names_refseq": "ASCL1; CASH-1; CASH1",
    "protein_names_uniprotkb": "Achaete-scute family bHLH transcription factor 1",
    "protein_names_refseq": "achaete-scute complex-like 1; achaete-scute complex homolog 1; achaete-scute homolog 1",
    "tax_id": 9031,
    "disease": "",
    "pathway": "",
    "pathway_count": 0,
    "publication_count": 4,
    "publication_id_list": "15033166;15922575;19093008;20214951",
    "function": "##Evidence-Data-START## Transcript exon combination :: U01339.1, L11871.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Sep 30, 2021 this sequence version replaced NP_989743.1., [RefSeq]; A BMP-mediated transcriptional cascade involving Cash1 and Tlx-3 specifies first-order relay sensory neurons in the developing brainstem, [RefSeq, PubMed]; Induces neuronal differentiation characterized by the expression of generic neuronal genes SCG10, Hu and NF160, [RefSeq, PubMed]; There is a functional relationship between specific MTG and bHLH proteins in developing chick spinal cord., [RefSeq, PubMed]; This study explores the possibility of reprogramming retinal pigment epithelium progeny cells to differentiate toward retinal neurons with achaete-scute homolog 1 (ash1), a proneural gene that is expressed in progenitor cells in the developing retina., [RefSeq, PubMed]",
    "predicted_glycosites": 0,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 0,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 0,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 0,
    "glyco_site_count": 0,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [],
    "go_molecular_function": "GO:0003682 chromatin binding;GO:0046983 protein dimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
    "go_cellular_component": "GO:0043025 neuronal cell body;GO:0090575 RNA polymerase II transcription regulator complex",
    "go_biological_process": "GO:0097475 motor neuron migration;GO:0007219 Notch signaling pathway;GO:0043066 negative regulation of apoptotic process;GO:0045665 negative regulation of neuron differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II",
    "synthesized_glycan_count": 0,
    "record_id": "A0A1D5P4G9-1",
    "record_type": "protein",
    "filter_code": "0000000.0000100.100000.0001000000000000.00000.000"
}
