{
    "uniprot_canonical_ac": "A0A1B0GWP1-1",
    "uniprot_id": [
        {
            "id": "A0A1B0GWP1_RAT",
            "url": "https://www.uniprot.org/uniprot/A0A1B0GWP1_RAT",
            "type": "external"
        }
    ],
    "mass": 47306.0,
    "length": 412,
    "protein_name": "Elongation of very long chain fatty acids protein 1",
    "gene_name": "Elovl1",
    "organism": "Rat",
    "refseq_name": "",
    "refseq_ac": [],
    "gene_names_uniprotkb": "Elovl1; ELOVL1",
    "gene_names_refseq": "",
    "protein_names_uniprotkb": "Elongation of very long chain fatty acids protein 1; 2.3.1.199; 3-keto acyl-CoA synthase ELOVL1; ELOVL FA elongase 1; ELOVL fatty acid elongase 1; Very long chain 3-ketoacyl-CoA synthase 1; Very long chain 3-oxoacyl-CoA synthase 1",
    "protein_names_refseq": "",
    "tax_id": 10116,
    "disease": "adrenoleukodystrophy (Disease Ontology:DOID:10588)",
    "pathway": " (R-RNO-2046105);  (R-RNO-2046106);  (R-RNO-75876)",
    "pathway_count": 3,
    "publication_count": 0,
    "publication_id_list": "",
    "function": "Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs., [UniProtKB, HAMAP, UniProtKB]",
    "predicted_glycosites": 0,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 0,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 0,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 1,
    "glyco_site_count": 0,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [
        {
            "id": "2.3.1.199",
            "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.199",
            "type": "external"
        }
    ],
    "go_molecular_function": "GO:0009922 fatty acid elongase activity",
    "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane",
    "go_biological_process": "GO:0046513 ceramide biosynthetic process;GO:0061436 establishment of skin barrier;GO:0030148 sphingolipid biosynthetic process;GO:0034625 fatty acid elongation, monounsaturated fatty acid;GO:0034626 fatty acid elongation, polyunsaturated fatty acid",
    "synthesized_glycan_count": 0,
    "record_id": "A0A1B0GWP1-1",
    "record_type": "protein",
    "filter_code": "0000000.0000011.100000.0000000000001000.00000.000"
}