{
    "uniprot_canonical_ac": "A0A140LI88-1",
    "uniprot_id": [
        {
            "id": "ANR31_MOUSE",
            "url": "https://www.uniprot.org/uniprot/ANR31_MOUSE",
            "type": "external"
        }
    ],
    "mass": 206173.0,
    "length": 1857,
    "protein_name": "Ankyrin repeat domain-containing protein 31",
    "gene_name": "Ankrd31",
    "organism": "Mouse",
    "refseq_name": "ankyrin repeat domain-containing protein 31",
    "refseq_ac": [
        {
            "id": "NP_001357857",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001357857",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "Ankrd31",
    "gene_names_refseq": "Ankrd31",
    "protein_names_uniprotkb": "Ankyrin repeat domain-containing protein 31",
    "protein_names_refseq": "ankyrin repeat domain-containing protein 31",
    "tax_id": 10090,
    "disease": "",
    "pathway": "",
    "pathway_count": 0,
    "publication_count": 4,
    "publication_id_list": "21750661;31000436;31003867;37976262",
    "function": "A crystal structure defines a pleckstrin homology (PH) domain in REC114 and its direct intermolecular contacts with ANKRD31. In vivo, ANKRD31 stabilizes REC114 association with the PAR and elsewhere. Our findings inform a model in which ANKRD31 is a scaffold anchoring REC114 and other factors to specific genomic locations, thereby regulating DSB formation., [RefSeq, PubMed]; Essential roles of the ANKRD31-REC114 interaction in meiotic recombination and mouse spermatogenesis., [RefSeq, PubMed]; Required for DNA double-strand breaks (DSBs) formation during meiotic recombination (PubMed:31000436, PubMed:31003867). Regulates the spatial and temporal patterns of pre-DSB recombinosome assembly and recombination activity by acting as a scaffold that anchors REC114 and other factors to specific genomic locations, thereby regulating DSB formation (PubMed:31000436, PubMed:31003867). Plays a key role in recombination in the pseudoautosomal regions of sex chromosomes (PubMed:31000436)., [UniProtKB, PubMed, PubMed]",
    "predicted_glycosites": 0,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 0,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 0,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 3,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 0,
    "glyco_site_count": 0,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [],
    "go_molecular_function": "",
    "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin",
    "go_biological_process": "GO:0007129 homologous chromosome pairing at meiosis;GO:0010780 meiotic DNA double-strand break formation involved in reciprocal meiotic recombination;GO:1903343 positive regulation of meiotic DNA double-strand break formation",
    "synthesized_glycan_count": 0,
    "record_id": "A0A140LI88-1",
    "record_type": "protein",
    "filter_code": "0000000.0100100.010000.0000000000100000.00000.000"
}