{
    "uniprot_canonical_ac": "A0A0R4IVV0-1",
    "uniprot_id": [
        {
            "id": "MTP_DANRE",
            "url": "https://www.uniprot.org/uniprot/MTP_DANRE",
            "type": "external"
        }
    ],
    "mass": 96988.0,
    "length": 884,
    "protein_name": "Microsomal triglyceride transfer protein large subunit",
    "gene_name": "mttp",
    "organism": "Zebrafish",
    "refseq_name": "microsomal triglyceride transfer protein large subunit precursor",
    "refseq_ac": [
        {
            "id": "NP_998135",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998135",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "mttp; mtp",
    "gene_names_refseq": "mtp; stl; wu:fd36b01; zgc:111876; zgc:136353; mttp",
    "protein_names_uniprotkb": "Microsomal triglyceride transfer protein large subunit",
    "protein_names_refseq": "microsomal triglyceride transfer protein large subunit precursor; stalactite; microsomal triglyceride transfer protein large subunit",
    "tax_id": 7955,
    "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); hypertension (Disease Ontology:DOID:10763); familial hyperlipidemia (Disease Ontology:DOID:1168); familial hypercholesterolemia (Disease Ontology:DOID:13810); abetalipoproteinemia (Disease Ontology:DOID:1386); hyperinsulinism (Disease Ontology:DOID:2018); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)",
    "pathway": " (dre:406207);  (R-DRE-8964041)",
    "pathway_count": 2,
    "publication_count": 5,
    "publication_id_list": "15614773;17176039;17924655;22581286;23594743",
    "function": "##Evidence-Data-START## Transcript exon combination :: AJ428850.1, GDQQ01025568.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU914777.9, FO704847.1, CABZ01049941.1, CABZ01050432.1 and BX908747.25. On or before Jul 27, 2018 this sequence version replaced NP_001038740.1, NP_998135.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Analysis of developmental expression and nutritional regulation of zebrafish homolog to mammalian microsomal triglyceride transfer protein large subunit, [RefSeq, PubMed]; Catalyzes the transport of triglyceride between phospholipid surfaces (PubMed:17924655). Catalyzes the transport of cholesteryl ester, and phospholipid between phospholipid surfaces (By similarity). Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B (PubMed:17924655, PubMed:22581286). Required for yolk lipid utilization and absorption of dietary lipids in larvae (PubMed:17176039)., [UniProtKB, PubMed, PubMed, UniProtKB, PubMed]; In a genetic study of lipid transport and metabolism, larval levels of microsomal triglyceride transfer protein (Mtp), the protein responsible for packaging triacylglycerol and beta-lipoproteins into lipoprotein particles, are unchanged by feeding., [RefSeq, PubMed]",
    "predicted_glycosites": 2,
    "predicted_n_glycosites": 2,
    "predicted_o_glycosites": 0,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 2,
    "total_o_glycosites": 0,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 8,
    "glyco_site_count": 2,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [],
    "go_molecular_function": "GO:0005319 lipid transporter activity;GO:0005548 phospholipid transporter activity;GO:0008289 lipid binding;GO:1904121 phosphatidylethanolamine transfer activity;GO:0120013 lipid transfer activity",
    "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016323 basolateral plasma membrane",
    "go_biological_process": "GO:0006629 lipid metabolic process;GO:0006869 lipid transport;GO:0042157 lipoprotein metabolic process;GO:0042158 lipoprotein biosynthetic process;GO:0042953 lipoprotein transport",
    "synthesized_glycan_count": 0,
    "record_id": "A0A0R4IVV0-1",
    "record_type": "protein",
    "filter_code": "0000000.0000111.100000.0000000000000001.00100.001"
}