{
    "uniprot_canonical_ac": "A0A0R4ILA2-1",
    "uniprot_id": [
        {
            "id": "A0A0R4ILA2_DANRE",
            "url": "https://www.uniprot.org/uniprot/A0A0R4ILA2_DANRE",
            "type": "external"
        }
    ],
    "mass": 89734.0,
    "length": 799,
    "protein_name": "Tyrosine-protein kinase receptor",
    "gene_name": "ntrk2b",
    "organism": "Zebrafish",
    "refseq_name": "neurotrophic tyrosine kinase, receptor, type 2b precursor",
    "refseq_ac": [
        {
            "id": "NP_001184090",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001184090",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "ntrk2b; si:ch211-220b11.1; si:ch73-270f14.4; trkB2",
    "gene_names_refseq": "ntrk2b; si:ch211-220b11.1; si:ch73-270f14.4; trkB2",
    "protein_names_uniprotkb": "Tyrosine-protein kinase receptor; 2.7.10.1",
    "protein_names_refseq": "neurotrophic tyrosine kinase, receptor, type 2b precursor; neurotrophic tyrosine kinase, receptor, type 2",
    "tax_id": 7955,
    "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); developmental and epileptic encephalopathy 58 (Disease Ontology:DOID:0080285); Alzheimer's disease (Disease Ontology:DOID:10652); morbid obesity (Disease Ontology:DOID:11981); autistic disorder (Disease Ontology:DOID:12849); major depressive disorder (Disease Ontology:DOID:1470); bipolar disorder (Disease Ontology:DOID:3312); cerebral infarction (Disease Ontology:DOID:3526); schizophrenia (Disease Ontology:DOID:5419); heroin dependence (Disease Ontology:DOID:9976)",
    "pathway": " (dre:570240)",
    "pathway_count": 1,
    "publication_count": 11,
    "publication_id_list": "16109975;16448862;16825768;20162349;23594743;34168553;34650032;35628418;35737348;36417881;7781913",
    "function": "##Evidence-Data-START## CDS exon combination :: GFIL01028832.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA4476729, SAMEA4476730 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU468920.7 and BX323563.11. On Nov 26, 2014 this sequence version replaced NP_001184090.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; The present results demonstrate that there is a parallel time-related decline in the expression of BDNF and TrkB in zebrafish., [RefSeq, PubMed]",
    "predicted_glycosites": 1,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 1,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 1,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 12,
    "glyco_site_count": 1,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [
        {
            "id": "2.7.10.1",
            "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1",
            "type": "external"
        },
        {
            "id": "2.7.12.1",
            "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1",
            "type": "external"
        },
        {
            "id": "2.7.10.2",
            "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2",
            "type": "external"
        },
        {
            "id": "2.7.12.2",
            "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2",
            "type": "external"
        },
        {
            "id": "2.7.11.23",
            "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23",
            "type": "external"
        },
        {
            "id": "2.7.11.1",
            "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
            "type": "external"
        }
    ],
    "go_molecular_function": "GO:0005011 macrophage colony-stimulating factor receptor activity;GO:0005007 fibroblast growth factor receptor activity;GO:0005009 insulin receptor activity;GO:0060175 brain-derived neurotrophic factor receptor activity;GO:0005524 ATP binding",
    "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0043235 receptor complex",
    "go_biological_process": "GO:1990416 cellular response to brain-derived neurotrophic factor stimulus;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007399 nervous system development;GO:0010976 positive regulation of neuron projection development;GO:0030154 cell differentiation",
    "synthesized_glycan_count": 0,
    "record_id": "A0A0R4ILA2-1",
    "record_type": "protein",
    "filter_code": "0000000.0000111.100000.0000000000000001.00010.001"
}
