{
    "uniprot_canonical_ac": "A0A0R4IL71-1",
    "uniprot_id": [
        {
            "id": "A0A0R4IL71_DANRE",
            "url": "https://www.uniprot.org/uniprot/A0A0R4IL71_DANRE",
            "type": "external"
        }
    ],
    "mass": 115533.0,
    "length": 998,
    "protein_name": "3.4.24.56; Insulin-degrading enzyme",
    "gene_name": "ide",
    "organism": "Zebrafish",
    "refseq_name": "insulin-degrading enzyme",
    "refseq_ac": [
        {
            "id": "NP_001082994",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082994",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "ide; CH211-129M12.3-001; CH211-129M12.3; zgc:162603",
    "gene_names_refseq": "ide; zgc:162603",
    "protein_names_uniprotkb": "3.4.24.56; Insulin-degrading enzyme",
    "protein_names_refseq": "insulin-degrading enzyme; insulysin",
    "tax_id": 7955,
    "disease": "diabetic encephalopathy (Disease Ontology:DOID:0050850); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); Alzheimer's disease (Disease Ontology:DOID:10652); type 2 diabetes mellitus (Disease Ontology:DOID:9352)",
    "pathway": " (dre:561390);  (R-DRE-5689880);  (R-DRE-77387)",
    "pathway_count": 3,
    "publication_count": 11,
    "publication_id_list": "18065431;23594743;24714733;26469318;26963759;27189481;30061596;30721868;31154177;33524730;35295584",
    "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01003509.1, BC139607.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX005050.6. On or before Jun 24, 2024 this sequence version replaced XP_005169584.1, NP_001082994.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
    "predicted_glycosites": 0,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 0,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 0,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 4,
    "glyco_site_count": 0,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [
        {
            "id": "3.4.24.56",
            "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.56",
            "type": "external"
        },
        {
            "id": "3.4.19.12",
            "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12",
            "type": "external"
        },
        {
            "id": "2.3.2.27",
            "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27",
            "type": "external"
        },
        {
            "id": "3.1.1.29",
            "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.29",
            "type": "external"
        },
        {
            "id": "3.6.5.-",
            "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-",
            "type": "external"
        },
        {
            "id": "5.2.1.8",
            "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8",
            "type": "external"
        },
        {
            "id": "3.4.23.5",
            "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.5",
            "type": "external"
        }
    ],
    "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding",
    "go_cellular_component": "GO:0005739 mitochondrion;GO:0005782 peroxisomal matrix;GO:0005829 cytosol",
    "go_biological_process": "GO:1990798 pancreas regeneration;GO:0050435 amyloid-beta metabolic process;GO:0042447 hormone catabolic process;GO:0043171 peptide catabolic process;GO:0031018 endocrine pancreas development",
    "synthesized_glycan_count": 0,
    "record_id": "A0A0R4IL71-1",
    "record_type": "protein",
    "filter_code": "0000000.0000111.010000.0000000000000001.00000.000"
}