{
    "uniprot_canonical_ac": "A0A0R4IKA2-1",
    "uniprot_id": [
        {
            "id": "A0A0R4IKA2_DANRE",
            "url": "https://www.uniprot.org/uniprot/A0A0R4IKA2_DANRE",
            "type": "external"
        }
    ],
    "mass": 95545.0,
    "length": 854,
    "protein_name": "RE1-silencing transcription factor",
    "gene_name": "rest",
    "organism": "Zebrafish",
    "refseq_name": "RE1-silencing transcription factor",
    "refseq_ac": [
        {
            "id": "NP_001340795",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001340795",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "rest; NRSF",
    "gene_names_refseq": "NRSF; rest",
    "protein_names_uniprotkb": "RE1-silencing transcription factor",
    "protein_names_refseq": "RE-1 silencer of transcription; neural-restrictive silencer factor; RE1-silencing transcription factor",
    "tax_id": 7955,
    "disease": "gingival fibromatosis 5 (Disease Ontology:DOID:0080280); autosomal dominant nonsyndromic deafness 27 (Disease Ontology:DOID:0110556); alcohol use disorder (Disease Ontology:DOID:1574); nephroblastoma (Disease Ontology:DOID:2154)",
    "pathway": "",
    "pathway_count": 0,
    "publication_count": 11,
    "publication_id_list": "16525062;20122919;20463883;21199918;21521740;23594743;25712696;25769695;27605615;31403159;36640352",
    "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01032517.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476811 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL954718.42. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Commensal Bacteria Regulate Gene Expression and Differentiation in Vertebrate Olfactory Systems Through Transcription Factor REST., [RefSeq, PubMed]; Rest functions in zebrafish facial branchiomotor neurons nuclei to inhibit maturation until the neurons complete their migration., [RefSeq, PubMed]; Study provides behavioral analysis of zebrafish rest mutants and reveals specific behaviors that are modulated by Rest, suggests that Rest has functions in regulating an organism's ability to interact with its environment, [RefSeq, PubMed]; The transcriptional repressor rest modulates hedgehog signaling., [RefSeq, PubMed]; This study demostrated that maternal rest plays a long-term role in regulation of gene expression through snap25a/b and behavior during development., [RefSeq, PubMed]",
    "predicted_glycosites": 2,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 2,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 2,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 4,
    "glyco_site_count": 2,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [],
    "go_molecular_function": "GO:0008270 zinc ion binding",
    "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
    "go_biological_process": "",
    "synthesized_glycan_count": 0,
    "record_id": "A0A0R4IKA2-1",
    "record_type": "protein",
    "filter_code": "0000000.0000110.100000.0000000000000001.00010.001"
}
