{
    "uniprot_canonical_ac": "A0A0R4IC31-1",
    "uniprot_id": [
        {
            "id": "A0A0R4IC31_DANRE",
            "url": "https://www.uniprot.org/uniprot/A0A0R4IC31_DANRE",
            "type": "external"
        }
    ],
    "mass": 172154.0,
    "length": 1596,
    "protein_name": "A kinase (PRKA) anchor protein 12b; A-kinase anchor protein 12b isoform 1",
    "gene_name": "akap12b",
    "organism": "Zebrafish",
    "refseq_name": "A-kinase anchor protein 12b isoform 1",
    "refseq_ac": [
        {
            "id": "NP_001268717",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268717",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "akap12b; akap12; cb27; esr1; fb72g12; id:ibd1202; sb:cb27; si:ch73-192g21.1; wu:fb72g12; wu:fc21c03",
    "gene_names_refseq": "akap12; cb27; esr1; fb72g12; id:ibd1202; sb:cb27; si:ch73-192g21.1; wu:fb72g12; wu:fc21c03; akap12b",
    "protein_names_uniprotkb": "A kinase (PRKA) anchor protein 12b; A-kinase anchor protein 12b isoform 1",
    "protein_names_refseq": "A-kinase anchor protein 12b isoform 1; gravin; A kinase (PRKA) anchor protein (gravin) 12; A kinase (PRKA) anchor protein (gravin) 12b",
    "tax_id": 7955,
    "disease": "juvenile myelomonocytic leukemia (Disease Ontology:DOID:0050458); colorectal carcinoma (Disease Ontology:DOID:0080199); chronic kidney disease (Disease Ontology:DOID:784)",
    "pathway": " (dre:567365)",
    "pathway_count": 1,
    "publication_count": 9,
    "publication_id_list": "17575056;18725198;22192928;23594743;25534553;26700682;28252024;28855284;31383248",
    "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01000772.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EB766946.1, CU041395.10 and CU179733.5. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Gravin is required for the conversion of mesodermal cells from a highly migratory behavior to the medio-laterally intercalative behavior required for body axis extension., [RefSeq, PubMed]; Loss of akap12 function causes severe defects in locomotor activity in zebrafish embryos., [RefSeq, PubMed]; The findings provide the first experimental evidence that akap12beta regulates heart laterality via cadherin1., [RefSeq, PubMed]; These results provide an important step forward in understanding the mechanism of Gravin function in cell shape regulation and provide valuable insight into how Gravin acts as a cytoskeletal regulator., [RefSeq, PubMed]; Zebrafish embryos depleted of akap12 (akap12 morphants) exhibited severe hemorrhages., [RefSeq, PubMed]",
    "predicted_glycosites": 3,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 3,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 3,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 3,
    "glyco_site_count": 3,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [],
    "go_molecular_function": "GO:0005516 calmodulin binding;GO:0051018 protein kinase A binding",
    "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0048471 perinuclear region of cytoplasm",
    "go_biological_process": "GO:0007165 signal transduction;GO:0010739 positive regulation of protein kinase A signaling;GO:0000902 cell morphogenesis;GO:0009887 animal organ morphogenesis;GO:0010738 regulation of protein kinase A signaling",
    "synthesized_glycan_count": 0,
    "record_id": "A0A0R4IC31-1",
    "record_type": "protein",
    "filter_code": "0000000.0000111.010000.0000000000000001.00010.001"
}