{
    "uniprot_canonical_ac": "A0A0G2L0Q2-1",
    "uniprot_id": [
        {
            "id": "A0A0G2L0Q2_DANRE",
            "url": "https://www.uniprot.org/uniprot/A0A0G2L0Q2_DANRE",
            "type": "external"
        }
    ],
    "mass": 28394.0,
    "length": 242,
    "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase",
    "gene_name": "hacd1",
    "organism": "Zebrafish",
    "refseq_name": "very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1",
    "refseq_ac": [
        {
            "id": "NP_001314793",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314793",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "hacd1; ptpla",
    "gene_names_refseq": "hacd1; ptpla",
    "protein_names_uniprotkb": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; 4.2.1.134",
    "protein_names_refseq": "protein tyrosine phosphatase-like, member A; protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1",
    "tax_id": 7955,
    "disease": "congenital myopathy (Disease Ontology:DOID:0081337)",
    "pathway": " (dre:553326)",
    "pathway_count": 1,
    "publication_count": 4,
    "publication_id_list": "12477932;21873635;23594743;34016526",
    "function": "##Evidence-Data-START## Transcript exon combination :: EH591206.1, EL646435.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR376779.18. On May 27, 2016 this sequence version replaced XP_699783.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators., [UniProtKB, UniProtKB, UniProtKB]",
    "predicted_glycosites": 0,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 0,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 0,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 1,
    "glyco_site_count": 0,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [
        {
            "id": "4.2.1.134",
            "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.134",
            "type": "external"
        }
    ],
    "go_molecular_function": "GO:0018812 3-hydroxyacyl-CoA dehydratase activity;GO:0102158 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity",
    "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane",
    "go_biological_process": "GO:0030148 sphingolipid biosynthetic process;GO:0030497 fatty acid elongation;GO:0042761 very long-chain fatty acid biosynthetic process",
    "synthesized_glycan_count": 0,
    "record_id": "A0A0G2L0Q2-1",
    "record_type": "protein",
    "filter_code": "0000000.0000111.100000.0000000000000001.00000.000"
}