{
    "uniprot_canonical_ac": "A0A0G2K583-1",
    "uniprot_id": [
        {
            "id": "A0A0G2K583_RAT",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K583_RAT",
            "type": "external"
        }
    ],
    "mass": 31089.0,
    "length": 283,
    "protein_name": "S-methyl-5'-thioadenosine phosphorylase",
    "gene_name": "Mtap",
    "organism": "Rat",
    "refseq_name": "S-methyl-5'-thioadenosine phosphorylase",
    "refseq_ac": [
        {
            "id": "NP_001380978",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001380978",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "Mtap; MTAP; Mtap_predicted",
    "gene_names_refseq": "Cc1-6; Mtap",
    "protein_names_uniprotkb": "S-methyl-5'-thioadenosine phosphorylase; 2.4.2.28; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAPase; MTAP",
    "protein_names_refseq": "5'-methylthioadenosine phosphorylase; S-methyl-5'-thioadenosine phosphorylase",
    "tax_id": 10116,
    "disease": "biliary tract benign neoplasm (Disease Ontology:DOID:0050625); diaphyseal medullary stenosis with malignant fibrous histiocytoma (Disease Ontology:DOID:0080664); pancreatic cancer (Disease Ontology:DOID:1793); common bile duct neoplasm (Disease Ontology:DOID:4608)",
    "pathway": " (R-RNO-1237112)",
    "pathway_count": 1,
    "publication_count": 1,
    "publication_id_list": "27748820",
    "function": "Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates., [UniProtKB, HAMAP, UniProtKB, UniProtKB]; These protein profiles, and their interacting protein network, may facilitate the elucidation of the molecular mechanisms underlying the antiinflammatory effects of CC16., [RefSeq, PubMed]",
    "predicted_glycosites": 0,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 0,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 0,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 4,
    "glyco_site_count": 0,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [
        {
            "id": "2.4.2.28",
            "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.28",
            "type": "external"
        }
    ],
    "go_molecular_function": "GO:0017061 S-methyl-5-thioadenosine phosphorylase activity",
    "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005654 nucleoplasm",
    "go_biological_process": "GO:0006166 purine ribonucleoside salvage;GO:0032259 methylation;GO:0019509 L-methionine salvage from methylthioadenosine;GO:0033574 response to testosterone",
    "synthesized_glycan_count": 0,
    "record_id": "A0A0G2K583-1",
    "record_type": "protein",
    "filter_code": "0000000.0000111.100000.0000000000001000.00000.000"
}