{
    "uniprot_canonical_ac": "A0A0G2K470-1",
    "uniprot_id": [
        {
            "id": "A0A0G2K470_RAT",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K470_RAT",
            "type": "external"
        }
    ],
    "mass": 128839.0,
    "length": 1178,
    "protein_name": "Integrin subunit alpha 2",
    "gene_name": "Itga2",
    "organism": "Rat",
    "refseq_name": "integrin alpha-2 precursor",
    "refseq_ac": [
        {
            "id": "NP_001414220",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414220",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "Itga2",
    "gene_names_refseq": "CD49B; GPIa; HPA-5; Itga2",
    "protein_names_uniprotkb": "Integrin subunit alpha 2",
    "protein_names_refseq": "integrin alpha-2 precursor; platelet glycoprotein Ia; integrin alpha 2",
    "tax_id": 10116,
    "disease": "von Willebrand's disease 1 (Disease Ontology:DOID:0060573); von Willebrand's disease 2 (Disease Ontology:DOID:0060574); thrombosis (Disease Ontology:DOID:0060903); sensorineural hearing loss (Disease Ontology:DOID:10003); iron deficiency anemia (Disease Ontology:DOID:11758); Behcet's disease (Disease Ontology:DOID:13241); thrombocytopenia (Disease Ontology:DOID:1588); retinal vein occlusion (Disease Ontology:DOID:1727); Glanzmann's thrombasthenia (Disease Ontology:DOID:2219); arteriosclerosis (Disease Ontology:DOID:2349); placental insufficiency (Disease Ontology:DOID:3891); myocardial infarction (Disease Ontology:DOID:5844); intermediate coronary syndrome (Disease Ontology:DOID:8805); diabetic retinopathy (Disease Ontology:DOID:8947); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352)",
    "pathway": " (R-RNO-216083);  (R-RNO-3000170);  (R-RNO-3000178);  (R-RNO-8874081)",
    "pathway_count": 4,
    "publication_count": 4,
    "publication_id_list": "27169768;27827993;29023021;31964805",
    "function": "Bone marrow-mesenchymal stem cell treatment was able to accelerate the healing process of burns by increasing the thickness of the collagen and the percentage of integrin alpha2beta1, thus accelerating the cell migration involved during wound healing., [RefSeq, PubMed]; Ca(2+) waves coordinate purinergic receptor-evoked integrin activation and polarization. Publication Status: Online-Only, [RefSeq, PubMed]; Hydrostatic mechanical force enhances the viability and decreases the apoptosis of condylar chondrocytes through integrin-FAK-ERK/PI3K pathway. Publication Status: Online-Only, [RefSeq, PubMed]; The interaction of alpha2beta1 integrin to collagen I in the cellular microenvironment can regulate expression of LOX., [RefSeq, PubMed]",
    "predicted_glycosites": 0,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 0,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 0,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 16,
    "glyco_site_count": 0,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [],
    "go_molecular_function": "GO:0005178 integrin binding;GO:0046872 metal ion binding;GO:0001540 amyloid-beta binding;GO:0005518 collagen binding;GO:0043236 laminin binding",
    "go_cellular_component": "GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0009986 cell surface;GO:0030424 axon;GO:0043679 axon terminus",
    "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0045785 positive regulation of cell adhesion;GO:0045987 positive regulation of smooth muscle contraction;GO:0001666 response to hypoxia;GO:0014070 response to organic cyclic compound",
    "synthesized_glycan_count": 0,
    "record_id": "A0A0G2K470-1",
    "record_type": "protein",
    "filter_code": "0000000.0000111.010000.0000000000001000.00000.000"
}