{
    "uniprot_canonical_ac": "A0A0C4DHF6-1",
    "uniprot_id": [
        {
            "id": "A0A0C4DHF6_DROME",
            "url": "https://www.uniprot.org/uniprot/A0A0C4DHF6_DROME",
            "type": "external"
        }
    ],
    "mass": 137703.0,
    "length": 1262,
    "protein_name": "Dystroglycan 1",
    "gene_name": "Dg",
    "organism": "Fruit fly",
    "refseq_name": "dystroglycan, isoform D",
    "refseq_ac": [
        {
            "id": "NP_788363",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788363",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "Dg; CG18250; CT41273; DG; DmDG; Dmel\\CG18250; Dmel_CG18250; alpha-DG; atu; dgn; dg; dys",
    "gene_names_refseq": "Dg; alpha-DG; atu; CG18250; CT41273; dg; DG; dgn; DmDG; Dmel\\CG18250; dys",
    "protein_names_uniprotkb": "Dystroglycan 1; Dystroglycan; Dystrophin-associated glycoprotein 1",
    "protein_names_refseq": "CG18250-PD; Dg-PD; dystroglican; dystroglycan; alphaDystroglycan; dystroglycan-like; atsugari; dystroglycan, isoform D",
    "tax_id": 7227,
    "disease": "lissencephaly (Disease Ontology:DOID:0050453); Fukuyama congenital muscular dystrophy (Disease Ontology:DOID:0050559); muscular dystrophy-dystroglycanopathy type B1 (Disease Ontology:DOID:0050588); autosomal recessive limb-girdle muscular dystrophy type 2D (Disease Ontology:DOID:0110278); autosomal recessive limb-girdle muscular dystrophy type 2P (Disease Ontology:DOID:0110293); congenital muscular dystrophy-dystroglycanopathy type A9 (Disease Ontology:DOID:0111232); muscular dystrophy-dystroglycanopathy (Disease Ontology:DOID:0112374); bronchopulmonary dysplasia (Disease Ontology:DOID:11650); Duchenne muscular dystrophy (Disease Ontology:DOID:11723); primary biliary cholangitis (Disease Ontology:DOID:12236); dilated cardiomyopathy (Disease Ontology:DOID:12930); inclusion body myositis (Disease Ontology:DOID:3429); myocardial infarction (Disease Ontology:DOID:5844); muscular atrophy (Disease Ontology:DOID:767); type 2 diabetes mellitus (Disease Ontology:DOID:9352); muscular dystrophy (Disease Ontology:DOID:9884)",
    "pathway": " (dme:Dmel_CG18250);  (R-DME-3000178);  (R-DME-5173105);  (R-DME-9010553);  (R-DME-9913351)",
    "pathway_count": 5,
    "publication_count": 11,
    "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357",
    "function": "The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
    "predicted_glycosites": 2,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 2,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 2,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 16,
    "glyco_site_count": 2,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [],
    "go_molecular_function": "GO:0005509 calcium ion binding;GO:0043236 laminin binding;GO:0008307 structural constituent of muscle;GO:0005055 laminin receptor activity",
    "go_cellular_component": "GO:0016010 dystrophin-associated glycoprotein complex;GO:0005576 extracellular region;GO:0005654 nucleoplasm;GO:0005856 cytoskeleton;GO:0005886 plasma membrane",
    "go_biological_process": "GO:0046716 muscle cell cellular homeostasis;GO:0030036 actin cytoskeleton organization;GO:0045214 sarcomere organization;GO:0021675 nerve development;GO:0007411 axon guidance",
    "synthesized_glycan_count": 0,
    "record_id": "A0A0C4DHF6-1",
    "record_type": "protein",
    "filter_code": "0000000.0000111.010000.0000100000000000.00010.001"
}
