{
    "uniprot_canonical_ac": "A0A0B4K753-1",
    "uniprot_id": [
        {
            "id": "HEMOT_DROME",
            "url": "https://www.uniprot.org/uniprot/HEMOT_DROME",
            "type": "external"
        }
    ],
    "mass": 10050.0,
    "length": 88,
    "protein_name": "Hemotin",
    "gene_name": "hemo",
    "organism": "Fruit fly",
    "refseq_name": "hemotin, isoform A",
    "refseq_ac": [
        {
            "id": "NP_001247180",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001247180",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "hemo; CG43194",
    "gene_names_refseq": "CG43194; Dmel\\CG43194; FBgn0262823; hemo",
    "protein_names_uniprotkb": "Hemotin",
    "protein_names_refseq": "CG43194-PA; hemo-PA; hemotin, isoform A",
    "tax_id": 7227,
    "disease": "",
    "pathway": " (dme:Dmel_CG43194)",
    "pathway_count": 1,
    "publication_count": 3,
    "publication_id_list": "10731132;12537572;27015288",
    "function": "Negatively regulates early endosome maturation by binding to and repressing the activity of 14-3-3zeta which prevents the 14-3-3zeta-mediated activation of phosphoinositide 3-kinase Pi3K68D. This, in turn, inhibits the Pi3K68D-mediated conversion of phosphatidylinositol to phosphatidylinositol-3-phosphate and prevents progression of early endosomes through the maturation process which regulates subsequent steps of phagocytic processing., [UniProtKB, PubMed]",
    "predicted_glycosites": 1,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 1,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 1,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 0,
    "glyco_site_count": 1,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [],
    "go_molecular_function": "",
    "go_cellular_component": "GO:0031901 early endosome membrane",
    "go_biological_process": "GO:0006909 phagocytosis;GO:0050766 positive regulation of phagocytosis;GO:1900426 positive regulation of defense response to bacterium;GO:1904980 positive regulation of endosome organization",
    "synthesized_glycan_count": 0,
    "record_id": "A0A0B4K753-1",
    "record_type": "protein",
    "filter_code": "0000000.0000101.100000.0000100000000000.00010.001"
}
