{
    "uniprot_canonical_ac": "A0A096MJU6-1",
    "uniprot_id": [
        {
            "id": "A0A096MJU6_RAT",
            "url": "https://www.uniprot.org/uniprot/A0A096MJU6_RAT",
            "type": "external"
        }
    ],
    "mass": 95906.0,
    "length": 857,
    "protein_name": "PR domain zinc finger protein 1",
    "gene_name": "Prdm1",
    "organism": "Rat",
    "refseq_name": "",
    "refseq_ac": [],
    "gene_names_uniprotkb": "Prdm1",
    "gene_names_refseq": "",
    "protein_names_uniprotkb": "PR domain zinc finger protein 1; 2.1.1.-",
    "protein_names_refseq": "",
    "tax_id": 10116,
    "disease": "diffuse large B-cell lymphoma (Disease Ontology:DOID:0050745); nasal type extranodal NK/T-cell lymphoma (Disease Ontology:DOID:0080797); lung cancer (Disease Ontology:DOID:1324); lung adenocarcinoma (Disease Ontology:DOID:3910); hepatocellular carcinoma (Disease Ontology:DOID:684); systemic lupus erythematosus (Disease Ontology:DOID:9074); colorectal cancer (Disease Ontology:DOID:9256)",
    "pathway": " (rno:309871)",
    "pathway_count": 1,
    "publication_count": 0,
    "publication_id_list": "",
    "function": "Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions., [UniProtKB, UniProtKB, UniProtKB]",
    "predicted_glycosites": 0,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 0,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 0,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 0,
    "total_n_glycosites": 0,
    "total_o_glycosites": 0,
    "reported_fully_resolved_glycans": 0,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 0,
    "reported_interactions": 0,
    "missing_score": 10000,
    "biomarker_type": "",
    "glycan_count": 0,
    "disease_count": 7,
    "glyco_site_count": 0,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [],
    "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0016740 transferase activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000976 transcription cis-regulatory region binding",
    "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0005730 nucleolus",
    "go_biological_process": "GO:0003170 heart valve development;GO:0032823 regulation of natural killer cell differentiation;GO:0033082 regulation of extrathymic T cell differentiation;GO:0051136 regulation of NK T cell differentiation;GO:1990654 sebum secreting cell proliferation",
    "synthesized_glycan_count": 0,
    "record_id": "A0A096MJU6-1",
    "record_type": "protein",
    "filter_code": "0000000.0000011.100000.0000000000001000.00000.000"
}
