{
    "uniprot_canonical_ac": "A0A087WXM9-1",
    "uniprot_id": [
        {
            "id": "MEIKN_HUMAN",
            "url": "https://www.uniprot.org/uniprot/MEIKN_HUMAN",
            "type": "external"
        }
    ],
    "mass": 40829.0,
    "length": 373,
    "protein_name": "Meiosis-specific kinetochore protein",
    "gene_name": "MEIKIN",
    "organism": "Human",
    "refseq_name": "meiosis-specific kinetochore protein",
    "refseq_ac": [
        {
            "id": "NP_001290551",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290551",
            "type": "external"
        }
    ],
    "gene_names_uniprotkb": "MEIKIN",
    "gene_names_refseq": "MEIKIN; SPO13",
    "protein_names_uniprotkb": "Meiosis-specific kinetochore protein",
    "protein_names_refseq": "meiosis-specific kinetochore protein",
    "tax_id": 9606,
    "disease": "",
    "pathway": " (hsa:728637)",
    "pathway_count": 1,
    "publication_count": 5,
    "publication_id_list": "11237011;18718982;25533956;30379171;32938616",
    "function": "Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase-mediated cleavage. Acts by facilitating kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Also required to prevent cleavage of cohesin at centromeres during meiosis I, possibly by acting as a regulator of the shugoshin-dependent protection pathway. Acts in collaboration with PLK1: required for PLK1 enrichment to kinetochores. Not required during meiosis II or mitosis., [UniProtKB, UniProtKB]; Single marker analysis indicated that SNP5 (rs1355095) in LOC728637 is associated with schizophrenia in Han Chinese., [RefSeq, PubMed]",
    "predicted_glycosites": 2,
    "predicted_n_glycosites": 0,
    "predicted_o_glycosites": 2,
    "mined_glycosites": 0,
    "mined_n_glycosites": 0,
    "mined_o_glycosites": 0,
    "reported_n_glycosites": 0,
    "reported_o_glycosites": 0,
    "reported_n_glycosites_with_glycan": 0,
    "reported_o_glycosites_with_glycan": 3,
    "total_reported_n_glycosites": 0,
    "total_reported_o_glycosites": 3,
    "total_n_glycosites": 0,
    "total_o_glycosites": 5,
    "reported_fully_resolved_glycans": 1,
    "reported_phosphosites": 0,
    "reported_mutagensis": 0,
    "reported_glycation": 0,
    "reported_snv": 8,
    "reported_interactions": 0,
    "missing_score": 0,
    "biomarker_type": "",
    "glycan_count": 1,
    "disease_count": 0,
    "glyco_site_count": 5,
    "binding_glycan_count": 0,
    "secondary_ac_list": "",
    "ec_number_list": [],
    "go_molecular_function": "",
    "go_cellular_component": "GO:0000776 kinetochore;GO:0000779 condensed chromosome, centromeric region",
    "go_biological_process": "GO:0051754 meiotic sister chromatid cohesion, centromeric;GO:0045143 homologous chromosome segregation;GO:0007060 male meiosis chromosome segregation;GO:0010789 meiotic sister chromatid cohesion involved in meiosis I;GO:0016321 female meiosis chromosome segregation",
    "synthesized_glycan_count": 0,
    "record_id": "A0A087WXM9-1",
    "record_type": "protein",
    "filter_code": "0000000.1000101.100000.0000000001000000.01010.001"
}
