{ "bcoid": "GLY_000404", "title": "Human UniProtKB Xref Pharos", "description": "The Human UniProtKB Xref Pharos dataset contains human [taxid:9606] UniProtKB canonical accessions cross-referenced ...", "filename_list": "human_protein_xref_pharos.csv", "filename": "human_protein_xref_pharos.csv", "filetype": "csv", "categories": { "species": [ "Homo sapiens" ], "molecule": [ "Protein" ], "tag": [ "Pharos cross-references" ], "file_type": [ "csv" ], "status": [ "Reviewed" ], "scope": [ "internal" ] }, "minitable": { "content": [ [ "P30613-1...", "protein_xref..." ], [ "Q96J66-1...", "protein_xref..." ] ], "headers": [ "uniprotkb_ca...", "xref_key..." ], "colwidth": [ "40%", "20%" ] }, "sampledata": { "type": "table", "data": [ [ { "type": "string", "label": "uniprotkb_canonical_ac" }, { "type": "string", "label": "xref_key" }, { "type": "string", "label": "xref_id" }, { "type": "string", "label": "xref_label" } ], [ "P30613-1", "protein_xref_pharos", "P30613", "Pyruvate kinase PKLR" ], [ "Q96J66-1", "protein_xref_pharos", "Q96J66", "ATP-binding cassette sub-family C member 11" ] ] }, "readme": "Name\n - Human UniProtKB Xref Pharos\n\nVersion\n - v-2.9.1\n\nCreated on\n - 2020-03-20T14:14:17.733990\n\nModified on\n - 2024-05-17T11:23:59.337Z\n\nCreated by\n - Jeet Vora [jeetvora@gwu.edu], Robel Kahsay [rykahsay@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Luke Johnson [luke.johnson@email.gwu.edu], Urnisha Bhuiyan [sbhuiyan28@email.gwu.edu], Cyrus Au-Yeung [cyruschauyeung@gwu.edu], Kate Warner [k.warner1@gwu.edu]\n\nAuthors\n - Tudor I Oprea [TOprea@salud.unm.edu], Paul Barrett [paul.barrett@nih.gov], Ajay Pillai [ajay.pillai3@nih.gov]\n\nChecksum\n - \n\nUsability Domain\n - The Human UniProtKB Xref Pharos dataset contains human [taxid:9606] UniProtKB canonical accessions cross-referenced to Pharos UniProtKB accessions. The data is from Pharos API based on TCRD version 5.4.0. If you use this dataset please provide proper attribution to Pharos and GlyGen\n - Pharos is the user interface to the Knowledge Management Center (KMC) for the Illuminating the Druggable Genome (IDG) program funded by the National Institutes of Health.\n - The goal of KMC is to develop a comprehensive, integrated knowledge-base for the Druggable Genome (DG) to illuminate the uncharacterized and/or poorly annotated portion of the DG, focusing on three of the most commonly drug-targeted protein families: G-protein-coupled receptors (GPCRs), ion channels (ICs) and kinases\n - Nguyen, D.-T., Mathias, S. et al, Pharos: Collating Protein Information to Shed Light on the Druggable Genome , Nucl. Acids Res.i>, 2017, 45(D1), D995-D1002. DOI: 10.1093/nar/gkw1072\n - https://pharos.nih.gov/about\n\nDescription Domain\n Keywords\n - Pharos\n - Illuminating the Druggable Genome\n - drug-targeted protein families\n - G-protein-coupled receptors (GPCRs)\n - ion channels (ICs)\n - kinases\n\n Pipeline Steps\n - Step-1: The script extracts the UniProtKB accessions and protein name from the Pharos API and maps to the GlyGen's UniProtKB canonical accessions (masterlist) to generate a csv dataset. The accessions that are not mapped are logged in the log file. \n\nExecution Domain\n Scripts - https://github.com/glygener/glygen-backend-integration/blob/master/dataset-maker/make-protein-dataset.py\n\n\n Software Prerequisites\n Name: Python\n Version: 2.7.5\n URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n Input Subdomain\n Name: batch.10.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.10.json\n Name: batch.11.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.11.json\n Name: batch.12.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.12.json\n Name: batch.13.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.13.json\n Name: batch.14.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.14.json\n Name: batch.15.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.15.json\n Name: batch.16.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.16.json\n Name: batch.17.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.17.json\n Name: batch.18.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.18.json\n Name: batch.19.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.19.json\n Name: batch.1.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.1.json\n Name: batch.20.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.20.json\n Name: batch.21.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.21.json\n Name: batch.2.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.2.json\n Name: batch.3.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.3.json\n Name: batch.4.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.4.json\n Name: batch.5.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.5.json\n Name: batch.6.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.6.json\n Name: batch.7.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.7.json\n Name: batch.8.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.8.json\n Name: batch.9.json\n URI: https:/data.glygen.org/ln2downloads/pharos/03_2020/batch.9.json\n Output Subdomain\n Name: human_protein_xref_pharos.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.9.1/reviewed/human_protein_xref_pharos.csv\n Name: human_protein_xref_pharos.stat.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.9.1/reviewed/human_protein_xref_pharos.stat.csv\n\nFields\n Name: \"uniprotkb_canonical_ac\"\n Description: \"\"\n Unique Values: \"19922\"\n Name: \"xref_key\"\n Description: \"Source key associated to the xref_id\"\n Unique Values: \"1\"\n Name: \"xref_id\"\n Description: \"ID of the X-ref\"\n Unique Values: \"19993\"\n Name: \"xref_label\"\n Description: \"Label/Name associated with x-ref\"\n Unique Values: \"19990\"", "downloadurl": "/ln2data/releases/data/v-2.9.1/reviewed/human_protein_xref_pharos.csv" }