{
    "bcoid": "GLY_000021",
    "title": "Human Protein Information (NCBI RefSeq)",
    "description": "The Human Protein Information (NCBI RefSeq) dataset contains Homo sapiens [taxid:9606] protein information ...",
    "filename_list": "human_protein_info_refseq.csv",
    "filename": "human_protein_info_refseq.csv",
    "filetype": "csv",
    "categories": {
        "species": [
            "Homo sapiens"
        ],
        "molecule": [
            "Protein"
        ],
        "tag": [
            "Protein Information"
        ],
        "file_type": [
            "csv"
        ],
        "status": [
            "Reviewed"
        ],
        "scope": [
            "internal"
        ]
    },
    "minitable": {
        "content": [
            [
                "Q68DV7-1...",
                "NP_001292473..."
            ],
            [
                "O75414-1...",
                "NP_001295355..."
            ]
        ],
        "headers": [
            "uniprotkb_ca...",
            "p_refseq_ac_..."
        ],
        "colwidth": [
            "40%",
            "20%"
        ]
    },
    "sampledata": {
        "type": "table",
        "data": [
            [
                {
                    "type": "string",
                    "label": "uniprotkb_canonical_ac"
                },
                {
                    "type": "string",
                    "label": "p_refseq_ac_best_match"
                },
                {
                    "type": "string",
                    "label": "refseq_protein_name"
                },
                {
                    "type": "string",
                    "label": "refseq_protein_length"
                },
                {
                    "type": "string",
                    "label": "refseq_protein_summary"
                }
            ],
            [
                "Q68DV7-1",
                "NP_001292473",
                "E3 ubiquitin-protein ligase RNF43 isoform 1 precursor",
                "783",
                "The protein encoded by this gene is a RING-type E3 ubiquitin ligase and is predicted to contain a transmembrane domain, a protease-associated domain, an ectodomain, and a cytoplasmic RING domain. This protein is thought to negatively regulate Wnt signaling, and expression of this gene results in an increase in ubiquitination of frizzled receptors, an alteration in their subcellular distribution, resulting in reduced surface levels of these receptors. Mutations in this gene have been reported in multiple tumor cells, including colorectal and endometrial cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]. "
            ],
            [
                "O75414-1",
                "NP_001295355",
                "nucleoside diphosphate kinase 6 isoform 2",
                "186",
                "Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6), such as NME6, are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates (Mehus et al., 1999 [PubMed 10453732]).[supplied by OMIM, Jul 2010]. "
            ]
        ]
    },
    "readme": "Name\n   - Human Protein Information (NCBI RefSeq)\n\nVersion\n   - v-2.9.1\n\nCreated on\n  - 2019-01-23T17:21:05.888176\n\nModified on\n   - 2024-05-17T11:23:49.489Z\n\nCreated by\n   - Jeet Vora [jeetvora@gwu.edu], Robel Kahsay [rykahsay@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Luke Johnson [luke.johnson@email.gwu.edu], Urnisha Bhuiyan [sbhuiyan28@email.gwu.edu], Cyrus Au-Yeung [cyruschauyeung@gwu.edu], Kate Warner [k.warner1@gwu.edu]\n\nAuthors\n   - Not Applicable []\n\nChecksum\n   - \n\nUsability Domain\n   - The Human Protein Information (NCBI RefSeq) dataset contains Homo sapiens [taxid:9606] protein information such as protein accession, name, length and protein function summary from NCBI RefSeq database. If you use this dataset please provide proper attribution to NCBI RefSeq and GlyGen.\n\nDescription Domain\n   Keywords\n   - protein information\n   - protein length\n   - NCBI RefSeq\n   - protein summary\n\n   Pipeline Steps\n   - Step-1: The script parses the NCBI RefSeq gpff files to extract the accession, length, protein summary and then maps the NCBI RefSeq accesion to the UniProtKB Canonical accessions\n\nExecution Domain\n   Scripts   - https://github.com/glygener/glygen-backend-integration/blob/master/dataset-maker/make-protein-dataset.py\n\n\n   Software Prerequisites\n      Name: Python\n      Version: 2.7.5\n      URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n   Input Subdomain\n      Name: human_protein_xref_refseq.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.9.1/reviewed/human_protein_xref_refseq.csv\n      Name: refseq_protein_all_9606.gpff\n      URI: https:/data.glygen.org/ln2downloads/ncbi/refseq/2025_05_16/refseq_protein_all_9606.gpff\n   Output Subdomain\n      Name: human_protein_info_refseq.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.9.1/reviewed/human_protein_info_refseq.csv\n      Name: human_protein_info_refseq.stat.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.9.1/reviewed/human_protein_info_refseq.stat.csv\n\nFields\n      Name: \"uniprotkb_canonical_ac\"\n     Description: \"\"\n      Unique Values: \"19086\"\n      Name: \"p_refseq_ac_best_match\"\n     Description: \"Best match NCBI RefSeq protein accession to UniProtKB canonical accession\"\n      Unique Values: \"19086\"\n      Name: \"refseq_protein_name\"\n     Description: \"Name of the protein in NCBI RefSeq database\"\n      Unique Values: \"19083\"\n      Name: \"refseq_protein_length\"\n     Description: \"Length of the protein in NCBI RefSeq database\"\n      Unique Values: \"2067\"\n      Name: \"refseq_protein_summary\"\n     Description: \"Function of the protein in NCBI RefSeq database\"\n      Unique Values: \"11855\"",
    "downloadurl": "/ln2data/releases/data/v-2.9.1/reviewed/human_protein_info_refseq.csv"
}