{
    "title": "GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin.",
    "journal": "Oncogene",
    "date": "2000",
    "authors": "Ikeda S, Kishida M, Matsuura Y, Usui H, Kikuchi A",
    "reference": {
        "type": "PubMed",
        "id": "10698523",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10698523"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "P25054-1",
            "protein_name": "Adenomatous polyposis coli protein",
            "gene_name": "APC",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O75197-1",
            "protein_name": "Low-density lipoprotein receptor-related protein 5",
            "gene_name": "LRP5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q5JTC6-1",
            "protein_name": "APC membrane recruitment protein 1",
            "gene_name": "AMER1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14332-1",
            "protein_name": "Frizzled-2",
            "gene_name": "FZD2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q93098-1",
            "protein_name": "Protein Wnt-8b",
            "gene_name": "WNT8B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P30153-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform",
            "gene_name": "PPP2R1A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O14640-1",
            "protein_name": "Segment polarity protein dishevelled homolog DVL-1",
            "gene_name": "DVL1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P48729-1",
            "protein_name": "Casein kinase I isoform alpha",
            "gene_name": "CSNK1A1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P04628-1",
            "protein_name": "Proto-oncogene Wnt-1",
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            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9H1J5-1",
            "protein_name": "Protein Wnt-8a",
            "gene_name": "WNT8A",
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        },
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            "uniprot_canonical_ac": "Q14738-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform",
            "gene_name": "PPP2R5D",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q15173-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform",
            "gene_name": "PPP2R5B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P56704-1",
            "protein_name": "Protein Wnt-3a",
            "gene_name": "WNT3A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P49841-1",
            "protein_name": "Glycogen synthase kinase-3 beta",
            "gene_name": "GSK3B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13362-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform",
            "gene_name": "PPP2R5C",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q92997-1",
            "protein_name": "Segment polarity protein dishevelled homolog DVL-3",
            "gene_name": "DVL3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62714-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform",
            "gene_name": "PPP2CB",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O15169-1",
            "protein_name": "Axin-1",
            "gene_name": "AXIN1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P35222-1",
            "protein_name": "Catenin beta-1",
            "gene_name": "CTNNB1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q15172-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform",
            "gene_name": "PPP2R5A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P78368-1",
            "protein_name": "Casein kinase I isoform gamma-2",
            "gene_name": "CSNK1G2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P30154-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform",
            "gene_name": "PPP2R1B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O75474-1",
            "protein_name": "GSK-3-binding protein FRAT2",
            "gene_name": "FRAT2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P67775-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform",
            "gene_name": "PPP2CA",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13467-1",
            "protein_name": "Frizzled-5",
            "gene_name": "FZD5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UP38-1",
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            "gene_name": "FZD1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O75581-1",
            "protein_name": "Low-density lipoprotein receptor-related protein 6",
            "gene_name": "LRP6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q16537-1",
            "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform",
            "gene_name": "PPP2R5E",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q92837-1",
            "protein_name": "Proto-oncogene FRAT1",
            "gene_name": "FRAT1",
            "tax_name": "Human"
        },
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            "uniprot_canonical_ac": "Q03135-1",
            "protein_name": "Caveolin-1",
            "gene_name": "CAV1",
            "tax_name": "Human"
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            "uniprot_canonical_ac": "O14641-1",
            "protein_name": "Segment polarity protein dishevelled homolog DVL-2",
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            "tax_name": "Human"
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    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
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                    "database": "UniProtKB",
                    "id": "P25054",
                    "url": "https://www.uniprot.org/uniprot/P25054"
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            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "record_id": "pubmed.10698523",
    "abstract": "",
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    "mutagenesis": [],
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    "phosphorylation": [],
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