{
    "title": "Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity.",
    "journal": "Biochemistry",
    "date": "2000",
    "authors": "Arnold SM, Fessler LI, Fessler JH, Kaufman RJ",
    "reference": {
        "type": "PubMed",
        "id": "10694380",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10694380"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "P0CG47-1",
            "protein_name": "Polyubiquitin-B",
            "gene_name": "UBB",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q92611-1",
            "protein_name": "ER degradation-enhancing alpha-mannosidase-like protein 1",
            "gene_name": "EDEM1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62979-1",
            "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
            "gene_name": "RPS27A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9BV94-1",
            "protein_name": "ER degradation-enhancing alpha-mannosidase-like protein 2",
            "gene_name": "EDEM2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UKV5-1",
            "protein_name": "E3 ubiquitin-protein ligase AMFR",
            "gene_name": "AMFR",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0CG48-1",
            "protein_name": "Polyubiquitin-C",
            "gene_name": "UBC",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O00237-1",
            "protein_name": "E3 ubiquitin-protein ligase RNF103",
            "gene_name": "RNF103",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9NYU2-1",
            "protein_name": "UDP-glucose:glycoprotein glucosyltransferase 1",
            "gene_name": "UGGT1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8WU17-1",
            "protein_name": "E3 ubiquitin-protein ligase RNF139",
            "gene_name": "RNF139",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P62987-1",
            "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
            "gene_name": "UBA52",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9GZP9-1",
            "protein_name": "Derlin-2",
            "gene_name": "DERL2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13438-1",
            "protein_name": "Protein OS-9",
            "gene_name": "OS9",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UKM7-1",
            "protein_name": "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase",
            "gene_name": "MAN1B1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O60858-1",
            "protein_name": "E3 ubiquitin-protein ligase TRIM13",
            "gene_name": "TRIM13",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q86TM6-1",
            "protein_name": "E3 ubiquitin-protein ligase synoviolin",
            "gene_name": "SYVN1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9NYU1-1",
            "protein_name": "UDP-glucose:glycoprotein glucosyltransferase 2",
            "gene_name": "UGGT2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q96GF1-1",
            "protein_name": "E3 ubiquitin-protein ligase RNF185",
            "gene_name": "RNF185",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9UBV2-1",
            "protein_name": "Protein sel-1 homolog 1",
            "gene_name": "SEL1L",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O60337-4",
            "protein_name": "E3 ubiquitin-protein ligase MARCHF6",
            "gene_name": "MARCHF6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q99942-1",
            "protein_name": "E3 ubiquitin-protein ligase RNF5",
            "gene_name": "RNF5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9BZQ6-1",
            "protein_name": "ER degradation-enhancing alpha-mannosidase-like protein 3",
            "gene_name": "EDEM3",
            "tax_name": "Human"
        }
    ],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P0CG47",
                    "url": "https://www.uniprot.org/uniprot/P0CG47"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "mutagenesis": [
        {
            "start_pos": 1452,
            "end_pos": 1452,
            "sequence_org": "D",
            "sequence_mut": "A",
            "comment": "Inactive.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9NYU2",
                    "url": "https://www.uniprot.org/uniprot/Q9NYU2"
                },
                {
                    "database": "PubMed",
                    "id": "10694380",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10694380"
                }
            ],
            "uniprot_canonical_ac": "Q9NYU2-1"
        },
        {
            "start_pos": 1453,
            "end_pos": 1453,
            "sequence_org": "Q",
            "sequence_mut": "A",
            "comment": "4% active.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9NYU2",
                    "url": "https://www.uniprot.org/uniprot/Q9NYU2"
                },
                {
                    "database": "PubMed",
                    "id": "10694380",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10694380"
                }
            ],
            "uniprot_canonical_ac": "Q9NYU2-1"
        },
        {
            "start_pos": 1454,
            "end_pos": 1454,
            "sequence_org": "D",
            "sequence_mut": "A",
            "comment": "Inactive.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9NYU2",
                    "url": "https://www.uniprot.org/uniprot/Q9NYU2"
                },
                {
                    "database": "PubMed",
                    "id": "10694380",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10694380"
                }
            ],
            "uniprot_canonical_ac": "Q9NYU2-1"
        },
        {
            "start_pos": 1455,
            "end_pos": 1455,
            "sequence_org": "L",
            "sequence_mut": "A",
            "comment": "2% active.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9NYU2",
                    "url": "https://www.uniprot.org/uniprot/Q9NYU2"
                },
                {
                    "database": "PubMed",
                    "id": "10694380",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10694380"
                }
            ],
            "uniprot_canonical_ac": "Q9NYU2-1"
        },
        {
            "start_pos": 1456,
            "end_pos": 1456,
            "sequence_org": "P",
            "sequence_mut": "A",
            "comment": "41% active.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9NYU2",
                    "url": "https://www.uniprot.org/uniprot/Q9NYU2"
                },
                {
                    "database": "PubMed",
                    "id": "10694380",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10694380"
                }
            ],
            "uniprot_canonical_ac": "Q9NYU2-1"
        },
        {
            "start_pos": 1457,
            "end_pos": 1457,
            "sequence_org": "N",
            "sequence_mut": "A",
            "comment": "7% active.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9NYU2",
                    "url": "https://www.uniprot.org/uniprot/Q9NYU2"
                },
                {
                    "database": "PubMed",
                    "id": "10694380",
                    "url": "https://pubmed.ncbi.nlm.nih.gov/10694380"
                }
            ],
            "uniprot_canonical_ac": "Q9NYU2-1"
        }
    ],
    "record_id": "pubmed.10694380",
    "abstract": "",
    "glycosylation": [],
    "snv": [],
    "phosphorylation": [],
    "glycation": [],
    "section_stats": [
        {
            "table_id": "referenced_proteins",
            "table_stats": [
                {
                    "field": "total",
                    "count": 21
                }
            ],
            "sort_fields": [
                "uniprot_canonical_ac",
                "protein_name",
                "gene_name",
                "tax_name"
            ]
        },
        {
            "table_id": "referenced_glycans",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}
