{
    "title": "An asparagine-phenylalanine substitution accounts for catalytic differences between hGSTM3-3 and other human class mu glutathione S-transferases.",
    "journal": "Biochemistry",
    "date": "1999",
    "authors": "Patskovsky YV, Patskovska LN, Listowsky I",
    "reference": {
        "type": "PubMed",
        "id": "10587441",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10587441"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "P78417-1",
            "protein_name": "Glutathione S-transferase omega-1",
            "gene_name": "GSTO1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P0CG29-1",
            "protein_name": "Glutathione S-transferase theta-2",
            "gene_name": "GSTT2",
            "tax_name": "Human"
        },
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            "uniprot_canonical_ac": "O15217-1",
            "protein_name": "Glutathione S-transferase A4",
            "gene_name": "GSTA4",
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            "protein_name": "Glutathione S-transferase P",
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            "uniprot_canonical_ac": "Q03013-1",
            "protein_name": "Glutathione S-transferase Mu 4",
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            "tax_name": "Human"
        },
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            "uniprot_canonical_ac": "P0CG30-1",
            "protein_name": "Glutathione S-transferase theta-2B",
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        },
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            "uniprot_canonical_ac": "P10620-1",
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            "tax_name": "Human"
        },
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            "uniprot_canonical_ac": "P28161-1",
            "protein_name": "Glutathione S-transferase Mu 2",
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        },
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            "protein_name": "Glutathione S-transferase theta-1",
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        },
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        },
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        },
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        },
        {
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            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O60760-1",
            "protein_name": "Hematopoietic prostaglandin D synthase",
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            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O43708-1",
            "protein_name": "Maleylacetoacetate isomerase",
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            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q7RTV2-1",
            "protein_name": "Glutathione S-transferase A5",
            "gene_name": "GSTA5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P08263-1",
            "protein_name": "Glutathione S-transferase A1",
            "gene_name": "GSTA1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q99735-1",
            "protein_name": "Microsomal glutathione S-transferase 2",
            "gene_name": "MGST2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9Y2Q3-1",
            "protein_name": "Glutathione S-transferase kappa 1",
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            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q16772-1",
            "protein_name": "Glutathione S-transferase A3",
            "gene_name": "GSTA3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P10768-1",
            "protein_name": "S-formylglutathione hydrolase",
            "gene_name": "ESD",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P46439-1",
            "protein_name": "Glutathione S-transferase Mu 5",
            "gene_name": "GSTM5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P09210-1",
            "protein_name": "Glutathione S-transferase A2",
            "gene_name": "GSTA2",
            "tax_name": "Human"
        }
    ],
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        {
            "name": "Homo sapiens",
            "taxid": 9606,
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                    "database": "UniProtKB",
                    "id": "P78417",
                    "url": "https://www.uniprot.org/uniprot/P78417"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
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        {
            "start_pos": 120,
            "end_pos": 120,
            "sequence_org": "Y",
            "sequence_mut": "A",
            "comment": "No effect.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P21266",
                    "url": "https://www.uniprot.org/uniprot/P21266"
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        {
            "start_pos": 120,
            "end_pos": 120,
            "sequence_org": "Y",
            "sequence_mut": "F",
            "comment": "Strongly increased catalytic activity.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P21266",
                    "url": "https://www.uniprot.org/uniprot/P21266"
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        {
            "start_pos": 213,
            "end_pos": 213,
            "sequence_org": "N",
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            "comment": "Strongly increased catalytic activity.",
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                {
                    "database": "UniProtKB",
                    "id": "P21266",
                    "url": "https://www.uniprot.org/uniprot/P21266"
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        {
            "start_pos": 213,
            "end_pos": 213,
            "sequence_org": "N",
            "sequence_mut": "G",
            "comment": "No effect.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P21266",
                    "url": "https://www.uniprot.org/uniprot/P21266"
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    "abstract": "",
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