{
    "title": "Cdk2-dependent and -independent pathways in E2F-mediated S phase induction.",
    "journal": "The Journal of biological chemistry",
    "date": "2000",
    "authors": "Arata Y, Fujita M, Ohtani K, Kijima S, Kato JY",
    "reference": {
        "type": "PubMed",
        "id": "10692433",
        "url": "https://pubmed.ncbi.nlm.nih.gov/10692433"
    },
    "referenced_glycans": [],
    "referenced_proteins": [
        {
            "uniprot_canonical_ac": "Q9UKT4-1",
            "protein_name": "F-box only protein 5",
            "gene_name": "FBXO5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P49918-1",
            "protein_name": "Cyclin-dependent kinase inhibitor 1C",
            "gene_name": "CDKN1C",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P46527-1",
            "protein_name": "Cyclin-dependent kinase inhibitor 1B",
            "gene_name": "CDKN1B",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P38936-1",
            "protein_name": "Cyclin-dependent kinase inhibitor 1",
            "gene_name": "CDKN1A",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P28749-1",
            "protein_name": "Retinoblastoma-like protein 1",
            "gene_name": "RBL1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q15329-1",
            "protein_name": "Transcription factor E2F5",
            "gene_name": "E2F5",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P06493-1",
            "protein_name": "Cyclin-dependent kinase 1",
            "gene_name": "CDK1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P24385-1",
            "protein_name": "G1/S-specific cyclin-D1",
            "gene_name": "CCND1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O75461-1",
            "protein_name": "Transcription factor E2F6",
            "gene_name": "E2F6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q96GY3-1",
            "protein_name": "Protein lin-37 homolog",
            "gene_name": "LIN37",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13415-1",
            "protein_name": "Origin recognition complex subunit 1",
            "gene_name": "ORC1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P00374-1",
            "protein_name": "Dihydrofolate reductase",
            "gene_name": "DHFR",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q13547-1",
            "protein_name": "Histone deacetylase 1",
            "gene_name": "HDAC1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14186-1",
            "protein_name": "Transcription factor Dp-1",
            "gene_name": "TFDP1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P09884-1",
            "protein_name": "DNA polymerase alpha catalytic subunit",
            "gene_name": "POLA1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "O75419-1",
            "protein_name": "Cell division control protein 45 homolog",
            "gene_name": "CDC45",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P31350-1",
            "protein_name": "Ribonucleoside-diphosphate reductase subunit M2",
            "gene_name": "RRM2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q99741-1",
            "protein_name": "Cell division control protein 6 homolog",
            "gene_name": "CDC6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9H211-1",
            "protein_name": "DNA replication factor Cdt1",
            "gene_name": "CDT1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q09028-1",
            "protein_name": "Histone-binding protein RBBP4",
            "gene_name": "RBBP4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q08999-1",
            "protein_name": "Retinoblastoma-like protein 2",
            "gene_name": "RBL2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P24864-1",
            "protein_name": "G1/S-specific cyclin-E1",
            "gene_name": "CCNE1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q52LA3-1",
            "protein_name": "Protein lin-52 homolog",
            "gene_name": "LIN52",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q14188-1",
            "protein_name": "Transcription factor Dp-2",
            "gene_name": "TFDP2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P30281-1",
            "protein_name": "G1/S-specific cyclin-D3",
            "gene_name": "CCND3",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P30279-1",
            "protein_name": "G1/S-specific cyclin-D2",
            "gene_name": "CCND2",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P11802-1",
            "protein_name": "Cyclin-dependent kinase 4",
            "gene_name": "CDK4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P06400-1",
            "protein_name": "Retinoblastoma-associated protein",
            "gene_name": "RB1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q6MZP7-1",
            "protein_name": "Protein lin-54 homolog",
            "gene_name": "LIN54",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q01094-1",
            "protein_name": "Transcription factor E2F1",
            "gene_name": "E2F1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P04818-1",
            "protein_name": "Thymidylate synthase",
            "gene_name": "TYMS",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q16254-1",
            "protein_name": "Transcription factor E2F4",
            "gene_name": "E2F4",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P04183-1",
            "protein_name": "Thymidine kinase, cytosolic",
            "gene_name": "TK1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P78396-1",
            "protein_name": "Cyclin-A1",
            "gene_name": "CCNA1",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q5TKA1-1",
            "protein_name": "Protein lin-9 homolog",
            "gene_name": "LIN9",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q00534-1",
            "protein_name": "Cyclin-dependent kinase 6",
            "gene_name": "CDK6",
            "tax_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P12004-1",
            "protein_name": "Proliferating cell nuclear antigen",
            "gene_name": "PCNA",
            "tax_name": "Human"
        }
    ],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9UKT4",
                    "url": "https://www.uniprot.org/uniprot/Q9UKT4"
                }
            ],
            "common_name": "Human",
            "glygen_name": "Human",
            "reference_species": "Homo sapiens [9606]"
        }
    ],
    "record_id": "pubmed.10692433",
    "abstract": "",
    "glycosylation": [],
    "mutagenesis": [],
    "snv": [],
    "phosphorylation": [],
    "glycation": [],
    "section_stats": [
        {
            "table_id": "referenced_proteins",
            "table_stats": [
                {
                    "field": "total",
                    "count": 37
                }
            ],
            "sort_fields": [
                "uniprot_canonical_ac",
                "protein_name",
                "gene_name",
                "tax_name"
            ]
        },
        {
            "table_id": "referenced_glycans",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}