{ "uniprot_canonical_ac": "P01876-2", "uniprot_ac": "P01876", "uniprot_id": "IGHA1_HUMAN", "mass": { "chemical_mass": 42849.0, "monoisotopic_mass": 42849.0 }, "refseq": {}, "gene_names": [ { "name": "IGHA1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P01876", "id": "P01876" } ], "protein_names": [ { "name": "Immunoglobulin heavy constant alpha 1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/P01876/entry#names_and_taxonomy", "id": "P01876" }, { "name": "Ig alpha-1 chain C region BUR", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/P01876/entry#names_and_taxonomy", "id": "P01876" }, { "name": "Ig alpha-1 chain C region TRO", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/P01876/entry#names_and_taxonomy", "id": "P01876" }, { "name": "Ig alpha-1 chain C region", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/P01876/entry#names_and_taxonomy", "id": "P01876" } ], "function": [ { "annotation": "Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). 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"description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumor", 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"https://bgee.org/?page=gene&gene_id=ENSG00000211895" } ] }, { "tissue": { "name": "Esophagus", "namespace": "UBERON", "id": "0001043", "url": "http://purl.obolibrary.org/obo/UBERON_0001043" }, "score": "84.65", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000211895", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000211895" } ] }, { "tissue": { "name": "Rectum", "namespace": "UBERON", "id": "0001052", "url": "http://purl.obolibrary.org/obo/UBERON_0001052" }, "score": "99.92", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000211895", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000211895" } ] }, { "tissue": { "name": "Urinary bladder", "namespace": "UBERON", "id": "0001255", "url": "http://purl.obolibrary.org/obo/UBERON_0001255" }, "score": "88.71", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000211895", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000211895" } ] }, { "tissue": { "name": "Thyroid gland", "namespace": "UBERON", "id": "0002046", "url": "http://purl.obolibrary.org/obo/UBERON_0002046" }, "score": "88.79", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000211895", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000211895" } ] }, { "tissue": { "name": "Liver", "namespace": "UBERON", "id": "0002107", "url": "http://purl.obolibrary.org/obo/UBERON_0002107" }, "score": "91.68", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000211895", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000211895" } ] }, { "tissue": { "name": "Prostate gland", "namespace": "UBERON", "id": "0002367", "url": "http://purl.obolibrary.org/obo/UBERON_0002367" }, "score": "94.83", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000211895", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000211895" } ] }, { "tissue": { "name": "Thoracic mammary gland", "namespace": "UBERON", "id": "0005200", "url": "http://purl.obolibrary.org/obo/UBERON_0005200" }, "score": "97.27", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000211895", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000211895" } ] } ], "expression_disease": [ { "significant": "No", "trend": "up", "name": "Prostate cancer [DO disease name]", "url": "http://disease-ontology.org/term/DOID:10283", "evidence": [ { "database": "BioXpress", "id": "P01876", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/P01876" } ], "disease": [ { "disease_id": "DOID:10283", "recommended_name": { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate." }, "synonyms": [ { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "NGP - new growth of prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "hereditary prostate cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "malignant tumor of the prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate cancer, familial", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostate neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "prostatic neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10283", "name": "tumor of the prostate", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "HPC3", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, type 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, on chromosome 7", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "predisposing for prostate cancer", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, susceptibility to", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0700275", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700275", "name": "prostate cancer, hereditary", "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents." }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer aggressiveness", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene." }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "RNASEL familial prostate cancer", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "familial prostate cancer caused by mutation in RNASEL", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, type 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "Prca1", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", 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properties.", "journal": "Blood", "date": "2002", "authors": "Allhorn M, Berggard T, Nordberg J, Olsson ML, Akerstrom B", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "11877257", "url": "https://glygen.org/publication/PubMed/11877257" } ] }, { "title": "JAM2 interacts with alpha4beta1. 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II].", "journal": "Bulletin de la Societe de chimie biologique", "date": "1956", "authors": "JAYLE MF, BOUSSIER G, TONNELAT J", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "13342742", "url": "https://glygen.org/publication/PubMed/13342742" } ] }, { "title": "The binding of haemoglobin by plasma proteins (haptoglobins); its bearing on the renal threshold for haemoglobin and the aetiology of haemoglobinuria.", "journal": "British medical journal", "date": "1957", "authors": "ALLISON AC, REES WA", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "13472068", "url": "https://glygen.org/publication/PubMed/13472068" } ] }, { "title": "Structural biology of the cell adhesion protein CD2: from molecular recognition to protein folding and design.", "journal": "Current protein & peptide science", "date": "2003", "authors": "Wilkins AL, Yang W, Yang JJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "14529530", "url": "https://glygen.org/publication/PubMed/14529530" } ] }, { "title": "Platelet-monocyte complexes support monocyte adhesion to endothelium by enhancing secondary tethering and cluster formation.", "journal": "Arteriosclerosis, thrombosis, and vascular biology", "date": "2004", "authors": "da Costa Martins P, van den Berk N, Ulfman LH, Koenderman L, Hordijk PL, Zwaginga JJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "14615387", "url": "https://glygen.org/publication/PubMed/14615387" } ] }, { "title": "Human lectin-like oxidized low-density lipoprotein receptor-1 functions as a dimer in living cells.", "journal": "DNA and cell biology", "date": "2004", "authors": "Xie Q, Matsunaga S, Niimi S, Ogawa S, Tokuyasu K, Sakakibara Y, Machida S", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "15000751", "url": "https://glygen.org/publication/PubMed/15000751" } ] }, { "title": "A proteomic analysis of human bile.", "journal": "Molecular & cellular proteomics : MCP", "date": "2004", "authors": "Kristiansen TZ, Bunkenborg J, Gronborg M, Molina H, Thuluvath PJ, Argani P, Goggins MG, Maitra A, Pandey A", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876#ptm_processing" }, { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "reference": [ { "type": "PubMed", "id": "15084671", "url": "https://glygen.org/publication/PubMed/15084671" } ] }, { "title": "Molecular characterization of the haptoglobin.hemoglobin receptor CD163. Ligand binding properties of the scavenger receptor cysteine-rich domain region.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "Madsen M, Moller HJ, Nielsen MJ, Jacobsen C, Graversen JH, van den Berg T, Moestrup SK", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "15448162", "url": "https://glygen.org/publication/PubMed/15448162" } ] }, { "title": "The functional interaction of the beta 2 integrin lymphocyte function-associated antigen-1 with junctional adhesion molecule-A is mediated by the I domain.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2004", "authors": "Fraemohs L, Koenen RR, Ostermann G, Heinemann B, Weber C", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "15528364", "url": "https://glygen.org/publication/PubMed/15528364" } ] }, { "title": "The lipocalin alpha(1)-microglobulin binds heme in different species.", "journal": "Archives of biochemistry and biophysics", "date": "2004", "authors": "Larsson J, Allhorn M, Kerstrom B", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "15542058", "url": "https://glygen.org/publication/PubMed/15542058" } ] }, { "title": "Involvement of JAM-A in mononuclear cell recruitment on inflamed or atherosclerotic endothelium: inhibition by soluble JAM-A.", "journal": "Arteriosclerosis, thrombosis, and vascular biology", "date": "2005", "authors": "Ostermann G, Fraemohs L, Baltus T, Schober A, Lietz M, Zernecke A, Liehn EA, Weber C", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "15681301", "url": "https://glygen.org/publication/PubMed/15681301" } ] }, { "title": "pH- and metal ion-linked stability of the hemopexin-heme complex.", "journal": "Biochemistry", "date": "2005", "authors": "Rosell FI, Mauk MR, Mauk AG", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "15697213", "url": "https://glygen.org/publication/PubMed/15697213" } ] }, { "title": "Integrin alpha8beta1-fibronectin interactions promote cell survival via PI3 kinase pathway.", "journal": "Biochemical and biophysical research communications", "date": "2005", "authors": "Farias E, Lu M, Li X, Schnapp LM", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "15721307", "url": "https://glygen.org/publication/PubMed/15721307" } ] }, { "title": "Human erythrocyte glycophorins: protein and gene structure analyses.", "journal": "Transfusion medicine reviews", "date": "1992", "authors": "Cartron JP, Rahuel C", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "1591491", "url": "https://glygen.org/publication/PubMed/1591491" } ] }, { "title": "Identification of the receptor scavenging hemopexin-heme complexes.", "journal": "Blood", "date": "2005", "authors": "Hvidberg V, Maniecki MB, Jacobsen C, Hojrup P, Moller HJ, Moestrup SK", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "15947085", "url": "https://glygen.org/publication/PubMed/15947085" } ] }, { "title": "Human high density lipoproteins are platforms for the assembly of multi-component innate immune complexes.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Shiflett AM, Bishop JR, Pahwa A, Hajduk SL", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "16046400", "url": "https://glygen.org/publication/PubMed/16046400" } ] }, { "title": "CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin.", "journal": "Blood", "date": "2006", "authors": "Schaer DJ, Schaer CA, Buehler PW, Boykins RA, Schoedon G, Alayash AI, Schaffner A", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "16189277", "url": "https://glygen.org/publication/PubMed/16189277" } ] }, { "title": "beta 1 integrin function in vivo: adhesion, migration and more.", "journal": "Cancer metastasis reviews", "date": "2005", "authors": "Brakebusch C, Fassler R", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "16258728", "url": "https://glygen.org/publication/PubMed/16258728" } ] }, { "title": "Junctional adhesion molecules (JAM)-B and -C contribute to leukocyte extravasation to the skin and mediate cutaneous inflammation.", "journal": "The Journal of investigative dermatology", "date": "2005", "authors": "Ludwig RJ, Zollner TM, Santoso S, Hardt K, Gille J, Baatz H, Johann PS, Pfeffer J, Radeke HH, Schon MP, Kaufmann R, Boehncke WH, Podda M", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "16297198", "url": "https://glygen.org/publication/PubMed/16297198" } ] }, { "title": "The murine haemopexin receptor. Evidence that the haemopexin-binding site resides on a 20 kDa subunit and that receptor recycling is regulated by protein kinase C.", "journal": "The Biochemical journal", "date": "1991", "authors": "Smith A, Farooqui SM, Morgan WT", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "1646599", "url": "https://glygen.org/publication/PubMed/1646599" } ] }, { "title": "CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2006", "authors": "Messmer B, Eissmann P, Stark S, Watzl C", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "16585556", "url": "https://glygen.org/publication/PubMed/16585556" } ] }, { "title": "The SIRP family of receptors and immune regulation.", "journal": "Nature reviews. Immunology", "date": "2006", "authors": "Barclay AN, Brown MH", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "16691243", "url": "https://glygen.org/publication/PubMed/16691243" } ] }, { "title": "Signalling and functional diversity within the Axl subfamily of receptor tyrosine kinases.", "journal": "Cytokine & growth factor reviews", "date": "2006", "authors": "Hafizi S, Dahlback B", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "16737840", "url": "https://glygen.org/publication/PubMed/16737840" } ] }, { "title": "Haptoglobin-related protein is a high-affinity hemoglobin-binding plasma protein.", "journal": "Blood", "date": "2006", "authors": "Nielsen MJ, Petersen SV, Jacobsen C, Oxvig C, Rees D, Moller HJ, Moestrup SK", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "16778136", "url": "https://glygen.org/publication/PubMed/16778136" } ] }, { "title": "Junctional adhesion molecule-A regulates cell migration and resistance to shear stress.", "journal": "Journal of cellular physiology", "date": "2006", "authors": "Huang H, Cruz F, Bazzoni G", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "16783819", "url": "https://glygen.org/publication/PubMed/16783819" } ] }, { "title": "Constitutive endocytosis of CD163 mediates hemoglobin-heme uptake and determines the noninflammatory and protective transcriptional response of macrophages to hemoglobin.", "journal": "Circulation research", "date": "2006", "authors": "Schaer CA, Schoedon G, Imhof A, Kurrer MO, Schaer DJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "17008602", "url": "https://glygen.org/publication/PubMed/17008602" } ] }, { "title": "Differential glycosylation of polymeric and monomeric IgA: a possible role in glomerular inflammation in IgA nephropathy.", "journal": "Journal of the American Society of Nephrology : JASN", "date": "2006", "authors": "Oortwijn BD, Roos A, Royle L, van Gijlswijk-Janssen DJ, Faber-Krol MC, Eijgenraam JW, Dwek RA, Daha MR, Rudd PM, van Kooten C", "evidence": [ { "database": "GlyConnect", "id": "227", "url": "https://glyconnect.expasy.org/browser/proteins/227" } ], "reference": [ { "type": "PubMed", "id": "17050773", "url": "https://glygen.org/publication/PubMed/17050773" } ] }, { "title": "Gas6 and protein S. Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily.", "journal": "The FEBS journal", "date": "2006", "authors": "Hafizi S, Dahlback B", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "17064312", "url": "https://glygen.org/publication/PubMed/17064312" } ] }, { "title": "JAM-C regulates tight junctions and integrin-mediated cell adhesion and migration.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Mandicourt G, Iden S, Ebnet K, Aurrand-Lions M, Imhof BA", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "17099249", "url": "https://glygen.org/publication/PubMed/17099249" } ] }, { "title": "A unique loop extension in the serine protease domain of haptoglobin is essential for CD163 recognition of the haptoglobin-hemoglobin complex.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Nielsen MJ, Petersen SV, Jacobsen C, Thirup S, Enghild JJ, Graversen JH, Moestrup SK", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "17102136", "url": "https://glygen.org/publication/PubMed/17102136" } ] }, { "title": "PECAM-1, a key player in neuroinflammation.", "journal": "European journal of neurology", "date": "2006", "authors": "Kalinowska A, Losy J", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "17116209", "url": "https://glygen.org/publication/PubMed/17116209" } ] }, { "title": "GPI-anchored CEA family glycoproteins CEA and CEACAM6 mediate their biological effects through enhanced integrin alpha5beta1-fibronectin interaction.", "journal": "Journal of cellular physiology", "date": "2007", "authors": "Ordonez C, Zhai AB, Camacho-Leal P, Demarte L, Fan MM, Stanners CP", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "17167768", "url": "https://glygen.org/publication/PubMed/17167768" } ] }, { "title": "Impact of salt bridges on the equilibrium binding and adhesion of human CD2 and CD58.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Bayas MV, Kearney A, Avramovic A, van der Merwe PA, Leckband DE", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "17172599", "url": "https://glygen.org/publication/PubMed/17172599" } ] }, { "title": "P-selectin glycoprotein ligand-1 is expressed on endothelial cells and mediates monocyte adhesion to activated endothelium.", "journal": "Arteriosclerosis, thrombosis, and vascular biology", "date": "2007", "authors": "da Costa Martins P, Garcia-Vallejo JJ, van Thienen JV, Fernandez-Borja M, van Gils JM, Beckers C, Horrevoets AJ, Hordijk PL, Zwaginga JJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "17322099", "url": "https://glygen.org/publication/PubMed/17322099" } ] }, { "title": "Platelets recruit human dendritic cells via Mac-1/JAM-C interaction and modulate dendritic cell function in vitro.", "journal": "Arteriosclerosis, thrombosis, and vascular biology", "date": "2007", "authors": "Langer HF, Daub K, Braun G, Schonberger T, May AE, Schaller M, Stein GM, Stellos K, Bueltmann A, Siegel-Axel D, Wendel HP, Aebert H, Roecken M, Seizer P, Santoso S, Wesselborg S, Brossart P, Gawaz M", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "17379836", "url": "https://glygen.org/publication/PubMed/17379836" } ] }, { "title": "Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2007", "authors": "Seitz HM, Camenisch TD, Lemke G, Earp HS, Matsushima GK", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "17442946", "url": "https://glygen.org/publication/PubMed/17442946" } ] }, { "title": "TREM-1 ligand expression on platelets enhances neutrophil activation.", "journal": "Blood", "date": "2007", "authors": "Haselmayer P, Grosse-Hovest L, von Landenberg P, Schild H, Radsak MP", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "17452516", "url": "https://glygen.org/publication/PubMed/17452516" } ] }, { "title": "JAM-A mediates neutrophil transmigration in a stimulus-specific manner in vivo: evidence for sequential roles for JAM-A and PECAM-1 in neutrophil transmigration.", "journal": "Blood", "date": "2007", "authors": "Woodfin A, Reichel CA, Khandoga A, Corada M, Voisin MB, Scheiermann C, Haskard DO, Dejana E, Krombach F, Nourshargh S", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "17505016", "url": "https://glygen.org/publication/PubMed/17505016" } ] }, { "title": "The role of junctional adhesion molecules in vascular inflammation.", "journal": "Nature reviews. Immunology", "date": "2007", "authors": "Weber C, Fraemohs L, Dejana E", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "17525755", "url": "https://glygen.org/publication/PubMed/17525755" } ] }, { "title": "Structure of CD84 provides insight into SLAM family function.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Yan Q, Malashkevich VN, Fedorov A, Fedorov E, Cao E, Lary JW, Cole JL, Nathenson SG, Almo SC", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "17563375", "url": "https://glygen.org/publication/PubMed/17563375" } ] }, { "title": "Immunoglobulin somatic hypermutation.", "journal": "Annual review of genetics", "date": "2007", "authors": "Teng Grace, Papavasiliou F Nina", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "reference": [ { "type": "PubMed", "id": "17576170", "url": "https://glygen.org/publication/PubMed/17576170" } ] }, { "title": "The neutrophil-specific antigen CD177 is a counter-receptor for platelet endothelial cell adhesion molecule-1 (CD31).", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Sachs UJ, Andrei-Selmer CL, Maniar A, Weiss T, Paddock C, Orlova VV, Choi EY, Newman PJ, Preissner KT, Chavakis T, Santoso S", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "17580308", "url": "https://glygen.org/publication/PubMed/17580308" } ] }, { "title": "Epithelial cell adhesion molecule: more than a carcinoma marker and adhesion molecule.", "journal": "The American journal of pathology", "date": "2007", "authors": "Trzpis M, McLaughlin PM, de Leij LM, Harmsen MC", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "17600130", "url": "https://glygen.org/publication/PubMed/17600130" } ] }, { "title": "JAM family and related proteins in leukocyte migration (Vestweber series).", "journal": "Arteriosclerosis, thrombosis, and vascular biology", "date": "2007", "authors": "Bradfield PF, Nourshargh S, Aurrand-Lions M, Imhof BA", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "17615384", "url": "https://glygen.org/publication/PubMed/17615384" } ] }, { "title": "JAM-C regulates unidirectional monocyte transendothelial migration in inflammation.", "journal": "Blood", "date": "2007", "authors": "Bradfield PF, Scheiermann C, Nourshargh S, Ody C, Luscinskas FW, Rainger GE, Nash GB, Miljkovic-Licina M, Aurrand-Lions M, Imhof BA", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "17625065", "url": "https://glygen.org/publication/PubMed/17625065" } ] }, { "title": "Hemoglobin is a co-factor of human trypanosome lytic factor.", "journal": "PLoS pathogens", "date": "2007", "authors": "Widener J, Nielsen MJ, Shiflett A, Moestrup SK, Hajduk S", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "17845074", "url": "https://glygen.org/publication/PubMed/17845074" } ] }, { "title": "Hemopexin prevents endothelial damage and liver congestion in a mouse model of heme overload.", "journal": "The American journal of pathology", "date": "2008", "authors": "Vinchi F, Gastaldi S, Silengo L, Altruda F, Tolosano E", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "18556779", "url": "https://glygen.org/publication/PubMed/18556779" } ] }, { "title": "A strategy for precise and large scale identification of core fucosylated glycoproteins.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Jia W, Lu Z, Fu Y, Wang HP, Wang LH, Chi H, Yuan ZF, Zheng ZB, Song LN, Han HH, Liang YM, Wang JL, Cai Y, Zhang YK, Deng YL, Ying WT, He SM, Qian XH", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876#ptm_processing" }, { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "reference": [ { "type": "PubMed", "id": "19139490", "url": "https://glygen.org/publication/PubMed/19139490" } ] }, { "title": "Glycophorin B is the erythrocyte receptor of Plasmodium falciparum erythrocyte-binding ligand, EBL-1.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009", "authors": "Mayer DC, Cofie J, Jiang L, Hartl DL, Tracy E, Kabat J, Mendoza LH, Miller LH", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "19279206", "url": "https://glygen.org/publication/PubMed/19279206" } ] }, { "title": "Membrane permeabilization by trypanosome lytic factor, a cytolytic human high density lipoprotein.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Harrington JM, Howell S, Hajduk SL", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "19324878", "url": "https://glygen.org/publication/PubMed/19324878" } ] }, { "title": "Heme scavenging and the other facets of hemopexin.", "journal": "Antioxidants & redox signaling", "date": "2010", "authors": "Tolosano E, Fagoonee S, Morello N, Vinchi F, Fiorito V", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "19650691", "url": "https://glygen.org/publication/PubMed/19650691" } ] }, { "title": "Enrichment of glycopeptides for glycan structure and attachment site identification.", "journal": "Nature methods", "date": "2009", "authors": "Nilsson J, Ruetschi U, Halim A, Hesse C, Carlsohn E, Brinkmalm G, Larson G", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876#ptm_processing" }, { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" }, { "database": "UniCarbKB", "id": "GLY_000040", "url": "http://data.glygen.org/GLY_000040" }, { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "19838169", "url": "https://glygen.org/publication/PubMed/19838169" } ] }, { "title": "GlycoSpectrumScan: fishing glycopeptides from MS spectra of protease digests of human colostrum sIgA.", "journal": "Journal of proteome research", "date": "2010", "authors": "Deshpande N, Jensen PH, Packer NH, Kolarich D", "evidence": [ { "database": "GlyConnect", "id": "227", "url": "https://glyconnect.expasy.org/browser/proteins/227" }, { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "20030399", "url": "https://glygen.org/publication/PubMed/20030399" } ] }, { "title": "Structure and function of immunoglobulins.", "journal": "The Journal of allergy and clinical immunology", "date": "2010-02", "authors": "Schroeder Harry W, Cavacini Lisa", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "reference": [ { "type": "PubMed", "id": "20176268", "url": "https://glygen.org/publication/PubMed/20176268" } ] }, { "title": "Metal ions and electrolytes regulate the dissociation of heme from human hemopexin at physiological pH.", "journal": "The Journal of biological chemistry", "date": "2010", "authors": "Mauk MR, Mauk AG", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "20430887", "url": "https://glygen.org/publication/PubMed/20430887" } ] }, { "title": "Clustered O-glycans of IgA1: defining macro- and microheterogeneity by use of electron capture/transfer dissociation.", "journal": "Molecular & cellular proteomics : MCP", "date": "2010", "authors": "Takahashi K, Wall SB, Suzuki H, Smith AD 4th, Hall S, Poulsen K, Kilian M, Mobley JA, Julian BA, Mestecky J, Novak J, Renfrow MB", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876#ptm_processing" }, { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "reference": [ { "type": "PubMed", "id": "20823119", "url": "https://glygen.org/publication/PubMed/20823119" } ] }, { "title": "Signaling through LRP1: Protection from atherosclerosis and beyond.", "journal": "Biochemical pharmacology", "date": "2011", "authors": "Boucher P, Herz J", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "20920479", "url": "https://glygen.org/publication/PubMed/20920479" } ] }, { "title": "Pregnancy-specific glycoprotein 1 induces endothelial tubulogenesis through interaction with cell surface proteoglycans.", "journal": "The Journal of biological chemistry", "date": "2011", "authors": "Lisboa FA, Warren J, Sulkowski G, Aparicio M, David G, Zudaire E, Dveksler GS", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "21193412", "url": "https://glygen.org/publication/PubMed/21193412" } ] }, { "title": "Analysis of glycoprotein E-selectin ligands on human and mouse marrow cells enriched for hematopoietic stem/progenitor cells.", "journal": "Blood", "date": "2011", "authors": "Merzaban JS, Burdick MM, Gadhoum SZ, Dagia NM, Chu JT, Fuhlbrigge RC, Sackstein R", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "21659548", "url": "https://glygen.org/publication/PubMed/21659548" } ] }, { "title": "Naturally occurring structural isomers in serum IgA1 o-glycosylation.", "journal": "Journal of proteome research", "date": "2012", "authors": "Takahashi K, Smith AD, Poulsen K, Kilian M, Julian BA, Mestecky J, Novak J, Renfrow MB", "evidence": [ { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "22067045", "url": "https://glygen.org/publication/PubMed/22067045" } ] }, { "title": "Molecular programming of B cell memory.", "journal": "Nature reviews. Immunology", "date": "2011-12-09", "authors": "McHeyzer-Williams Michael, Okitsu Shinji, Wang Nathaniel, McHeyzer-Williams Louise", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "reference": [ { "type": "PubMed", "id": "22158414", "url": "https://glygen.org/publication/PubMed/22158414" } ] }, { "title": "Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Halim A, Nilsson J, Ruetschi U, Hesse C, Larson G", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876#ptm_processing" }, { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" }, { "database": "UniCarbKB", "id": "GLY_000040", "url": "http://data.glygen.org/GLY_000040" }, { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "22171320", "url": "https://glygen.org/publication/PubMed/22171320" } ] }, { "title": "The structure and function of human IgA.", "journal": "The Biochemical journal", "date": "1990-10-15", "authors": "Kerr M A", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "reference": [ { "type": "PubMed", "id": "2241915", "url": "https://glygen.org/publication/PubMed/2241915" } ] }, { "title": "Insertion of heme b into the structure of the Cys34-carbamidomethylated human lipocalin alpha(1)-microglobulin: formation of a [(heme)(2) (alpha(1)-Microglobulin)](3) complex.", "journal": "Chembiochem : a European journal of chemical biology", "date": "2012", "authors": "Siebel JF, Kosinsky RL, Akerstrom B, Knipp M", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "22492620", "url": "https://glygen.org/publication/PubMed/22492620" } ] }, { "title": "Structure of the haptoglobin-haemoglobin complex.", "journal": "Nature", "date": "2012", "authors": "Andersen CB, Torvund-Jensen M, Nielsen MJ, de Oliveira CL, Hersleth HP, Andersen NH, Pedersen JS, Andersen GR, Moestrup SK", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "22922649", "url": "https://glygen.org/publication/PubMed/22922649" } ] }, { "title": "Pregnancy-specific glycoprotein 1 (PSG1) activates TGF-beta and prevents dextran sodium sulfate (DSS)-induced colitis in mice.", "journal": "Mucosal immunology", "date": "2014", "authors": "Blois SM, Sulkowski G, Tirado-Gonzalez I, Warren J, Freitag N, Klapp BF, Rifkin D, Fuss I, Strober W, Dveksler GS", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "23945545", "url": "https://glygen.org/publication/PubMed/23945545" } ] }, { "title": "Biochemical analysis of the Plasmodium falciparum erythrocyte-binding antigen-175 (EBA175)-glycophorin-A interaction: implications for vaccine design.", "journal": "The Journal of biological chemistry", "date": "2013", "authors": "Wanaguru M, Crosnier C, Johnson S, Rayner JC, Wright GJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "24043627", "url": "https://glygen.org/publication/PubMed/24043627" } ] }, { "title": "Dominant negative effects of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 4 on TRAIL receptor 1 signaling by formation of heteromeric complexes.", "journal": "The Journal of biological chemistry", "date": "2014", "authors": "Neumann S, Hasenauer J, Pollak N, Scheurich P", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "24764293", "url": "https://glygen.org/publication/PubMed/24764293" } ] }, { "title": "Efficient and accurate glycopeptide identification pipeline for high-throughput site-specific N-glycosylation analysis.", "journal": "Journal of proteome research", "date": "2014", "authors": "Liu M, Zhang Y, Chen Y, Yan G, Shen C, Cao J, Zhou X, Liu X, Zhang L, Shen H, Lu H, He F, Yang P", "evidence": [ { "database": "UniCarbKB", "id": "GLY_000040", "url": "http://data.glygen.org/GLY_000040" }, { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "24766575", "url": "https://glygen.org/publication/PubMed/24766575" } ] }, { "title": "Comparison of sialylated N-glycopeptide levels in serum of pancreatic cancer patients, acute pancreatitis patients, and healthy controls.", "journal": "Proteomics", "date": "2014", "authors": "Kontro H, Joenvaara S, Haglund C, Renkonen R", "evidence": [ { "database": "UniCarbKB", "id": "GLY_000040", "url": "http://data.glygen.org/GLY_000040" }, { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "24841998", "url": "https://glygen.org/publication/PubMed/24841998" } ] }, { "title": "The roles of protein C and thrombomodulin in the regulation of blood coagulation.", "journal": "The Journal of biological chemistry", "date": "1989", "authors": "Esmon CT", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "2538457", "url": "https://glygen.org/publication/PubMed/2538457" } ] }, { "title": "O-linked oligosaccharides from human serum immunoglobulin A1.", "journal": "Biochemical Society transactions", "date": "1989", "authors": "Field MC, Dwek RA, Edge CJ, Rademacher TW", "evidence": [ { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "2628063", "url": "https://glygen.org/publication/PubMed/2628063" } ] }, { "title": "A Method for Comprehensive Glycosite-Mapping and Direct Quantitation of Serum Glycoproteins.", "journal": "Journal of proteome research", "date": "2015", "authors": "Hong Q, Ruhaak LR, Stroble C, Parker E, Huang J, Maverakis E, Lebrilla CB", "evidence": [ { "database": "GlyConnect", "id": "227", "url": "https://glyconnect.expasy.org/browser/proteins/227" } ], "reference": [ { "type": "PubMed", "id": "26510530", "url": "https://glygen.org/publication/PubMed/26510530" } ] }, { "title": "Comparative analysis of Cu (I)-catalyzed alkyne-azide cycloaddition (CuAAC) and strain-promoted alkyne-azide cycloaddition (SPAAC) in O-GlcNAc proteomics.", "journal": "Electrophoresis", "date": "2016", "authors": "Li S, Zhu H, Wang J, Wang X, Li X, Ma C, Wen L, Yu B, Wang Y, Li J, Wang PG", "evidence": [ { "database": "O-GlcNAc Database", "id": "P01876", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P01876" } ], "reference": [ { "type": "PubMed", "id": "26853435", "url": "https://glygen.org/publication/PubMed/26853435" } ] }, { "title": "Primary structure of twenty three neutral and monosialylated oligosaccharides O-glycosidically linked to the human secretory immunoglobulin A hinge region determined by a combination of permethylation analysis and 400-MHz 1H-NMR spectroscopy.", "journal": "European journal of biochemistry", "date": "1989", "authors": "Pierce-Cretel A, Decottignies JP, Wieruszeski JM, Strecker G, Montreuil J, Spik G", "evidence": [ { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "2737211", "url": "https://glygen.org/publication/PubMed/2737211" } ] }, { "title": "Proteomics Analysis of O-GalNAc Glycosylation in Human Serum by an Integrated Strategy.", "journal": "Analytical chemistry", "date": "2017", "authors": "Qin H, Cheng K, Zhu J, Mao J, Wang F, Dong M, Chen R, Guo Z, Liang X, Ye M, Zou H", "evidence": [ { "database": "UniCarbKB", "id": "GLY_000040", "url": "http://data.glygen.org/GLY_000040" } ], "reference": [ { "type": "PubMed", "id": "28035807", "url": "https://glygen.org/publication/PubMed/28035807" } ] }, { "title": "Serum proteins as mediators of hemin efflux from red cell membranes: specificity of hemopexin.", "journal": "FEBS letters", "date": "1989", "authors": "Solar I, Muller-Eberhard U, Shaklai N", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "2806549", "url": "https://glygen.org/publication/PubMed/2806549" } ] }, { "title": "Importance of ligand-induced conformational changes in hemopexin for receptor-mediated heme transport.", "journal": "The Journal of biological chemistry", "date": "1988", "authors": "Smith A, Tatum FM, Muster P, Burch MK, Morgan WT", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "2833500", "url": "https://glygen.org/publication/PubMed/2833500" } ] }, { "title": "Site-Specific Profiling of Serum Glycoproteins Using N-Linked Glycan and Glycosite Analysis Revealing Atypical N-Glycosylation Sites on Albumin and alpha-1B-Glycoprotein.", "journal": "Analytical chemistry", "date": "2018", "authors": "Sun S, Hu Y, Jia L, Eshghi ST, Liu Y, Shah P, Zhang H", "evidence": [ { "database": "UniCarbKB", "id": "GLY_000040", "url": "http://data.glygen.org/GLY_000040" }, { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "29671580", "url": "https://glygen.org/publication/PubMed/29671580" } ] }, { "title": "Reanalysis of Global Proteomic and Phosphoproteomic Data Identified a Large Number of Glycopeptides.", "journal": "Analytical chemistry", "date": "2018", "authors": "Hu Y, Shah P, Clark DJ, Ao M, Zhang H", "evidence": [ { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "29741879", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "title": "Tongue Cancer Patients Can be Distinguished from Healthy Controls by Specific N-Glycopeptides Found in Serum.", "journal": "Proteomics. Clinical applications", "date": "2018", "authors": "Saraswat M, Makitie A, Tohmola T, Dickinson A, Saraswat S, Joenvaara S, Renkonen S", "evidence": [ { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "29992770", "url": "https://glygen.org/publication/PubMed/29992770" } ] }, { "title": "Combinatorial regulation of hepatic cytoplasmic signaling and nuclear transcriptional events by the OGT/REV-ERBalpha complex.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2018", "authors": "Berthier A, Vinod M, Porez G, Steenackers A, Alexandre J, Yamakawa N, Gheeraert C, Ploton M, Marechal X, Dubois-Chevalier J, Hovasse A, Schaeffer-Reiss C, Cianferani S, Rolando C, Bray F, Duez H, Eeckhoute J, Lefebvre T, Staels B, Lefebvre P", "evidence": [ { "database": "O-GlcNAc Database", "id": "P01876", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P01876" } ], "reference": [ { "type": "PubMed", "id": "30397120", "url": "https://glygen.org/publication/PubMed/30397120" } ] }, { "title": "Mapping the O-glycoproteome using site-specific extraction of O-linked glycopeptides (EXoO).", "journal": "Molecular systems biology", "date": "2018", "authors": "Yang W, Ao M, Hu Y, Li QK, Zhang H", "evidence": [ { "database": "UniCarbKB", "id": "GLY_000040", "url": "http://data.glygen.org/GLY_000040" } ], "reference": [ { "type": "PubMed", "id": "30459171", "url": "https://glygen.org/publication/PubMed/30459171" } ] }, { "title": "Multi-isotype Glycoproteomic Characterization of Serum Antibody Heavy Chains Reveals Isotype- and Subclass-Specific N-Glycosylation Profiles.", "journal": "Molecular & cellular proteomics : MCP", "date": "2019", "authors": "Chandler KB, Mehta N, Leon DR, Suscovich TJ, Alter G, Costello CE", "evidence": [ { "database": "UniCarbKB", "id": "GLY_000040", "url": "http://data.glygen.org/GLY_000040" } ], "reference": [ { "type": "PubMed", "id": "30659065", "url": "https://glygen.org/publication/PubMed/30659065" } ] }, { "title": "Analysis of O-glycoforms of the IgA1 hinge region by sequential deglycosylation.", "journal": "Scientific reports", "date": "2020", "authors": "Ohyama Y, Yamaguchi H, Nakajima K, Mizuno T, Fukamachi Y, Yokoi Y, Tsuboi N, Inaguma D, Hasegawa M, Renfrow MB, Novak J, Yuzawa Y, Takahashi K", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876#ptm_processing" }, { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "reference": [ { "type": "PubMed", "id": "31959827", "url": "https://glygen.org/publication/PubMed/31959827" } ] }, { "title": "Structure of the secretory immunoglobulin A core.", "journal": "Science (New York, N.Y.)", "date": "2020", "authors": "Kumar N, Arthur CP, Ciferri C, Matsumoto ML", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "reference": [ { "type": "PubMed", "id": "32029686", "url": "https://glygen.org/publication/PubMed/32029686" } ] }, { "title": "Quantitative Longitudinal Inventory of the N-Glycoproteome of Human Milk from a Single Donor Reveals the Highly Variable Repertoire and Dynamic Site-Specific Changes.", "journal": "Journal of proteome research", "date": "2020", "authors": "Zhu J, Lin YH, Dingess KA, Mank M, Stahl B, Heck AJR", "evidence": [ { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "32125861", "url": "https://glygen.org/publication/PubMed/32125861" } ] }, { "title": "Aberrant RL2 O-GlcNAc antibody reactivity against serum-IgA1 of patients with colorectal cancer.", "journal": "Glycoconjugate journal", "date": "2021", "authors": "Verathamjamras C, Sriwitool TE, Netsirisawan P, Chaiyawat P, Chokchaichamnankit D, Prasongsook N, Srisomsap C, Svasti J, Champattanachai V", "evidence": [ { "database": "O-GlcNAc Database", "id": "P01876", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P01876" }, { "database": "O-GlcNAc Atlas", "id": "P01876", "url": "https://oglcnac.org/atlas/detail/P01876" }, { "database": "GlyGen", "id": "GLY_000481", "url": "https://data.glygen.org/GLY_000481" } ], "reference": [ { "type": "PubMed", "id": "33608772", "url": "https://glygen.org/publication/PubMed/33608772" } ] }, { "title": "Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis.", "journal": "Nature methods", "date": "2021", "authors": "Kawahara R, Chernykh A, Alagesan K, Bern M, Cao W, Chalkley RJ, Cheng K, Choo MS, Edwards N, Goldman R, Hoffmann M, Hu Y, Huang Y, Kim JY, Kletter D, Liquet B, Liu M, Mechref Y, Meng B, Neelamegham S, Nguyen-Khuong T, Nilsson J, Pap A, Park GW, Parker BL, Pegg CL, Penninger JM, Phung TK, Pioch M, Rapp E, Sakalli E, Sanda M, Schulz BL, Scott NE, Sofronov G, Stadlmann J, Vakhrushev SY, Woo CM, Wu HY, Yang P, Ying W, Zhang H, Zhang Y, Zhao J, Zaia J, Haslam SM, Palmisano G, Yoo JS, Larson G, Khoo KH, Medzihradszky KF, Kolarich D, Packer NH, Thaysen-Andersen M", "evidence": [ { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "34725484", "url": "https://glygen.org/publication/PubMed/34725484" } ] }, { "title": "Lectin-Based Affinity Enrichment and Characterization of N-Glycoproteins from Human Tear Film by Mass Spectrometry.", "journal": "Molecules (Basel, Switzerland)", "date": "2023-01-08", "authors": "Schmelter Carsten, Brueck Alina, Perumal Natarajan, Qu Sichang, Pfeiffer Norbert, Grus Franz H", "evidence": [ { "database": "GlyGen", "id": "GLY_000481", "url": "https://data.glygen.org/GLY_000481" } ], "reference": [ { "type": "PubMed", "id": "36677706", "url": "https://glygen.org/publication/PubMed/36677706" } ] }, { "title": "O-GlcNAc transferase regulates collagen deposition and fibrosis resolution in idiopathic pulmonary fibrosis.", "journal": "Frontiers in immunology", "date": "2024", "authors": "Vang Shia, Helton Eric Scott, Guo Yiming, Burpee Bailey, Rose Elex, Easter Molly, Bollenbecker Seth, Hirsch Meghan June, Matthews Emma Lea, Jones Luke Isaac, Howze Patrick Henry, Rajasekaran Vasanthi, Denson Rebecca, Cochran Phillip, Attah Isaac Kwame, Olson Heather, Clair Geremy, Melkani Girish, Krick Stefanie, Barnes Jarrod Wesley", "evidence": [ { "database": "O-GlcNAc Database", "id": "P01876", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P01876" } ], "reference": [ { "type": "PubMed", "id": "38665916", "url": "https://glygen.org/publication/PubMed/38665916" } ] }, { "title": "Hemopexin-mediated heme transport to the liver. Evidence for a heme-binding protein in liver plasma membranes.", "journal": "The Journal of biological chemistry", "date": "1985", "authors": "Smith A, Morgan WT", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "3891754", "url": "https://glygen.org/publication/PubMed/3891754" } ] }, { "title": "[Rule of antibody structure. Primary structure of a human monoclonal IgA-immunoglobulin (myeloma protein Tro). VII. Purification and characterization of the disulfide bridges].", "journal": "Hoppe-Seyler's Zeitschrift fur physiologische Chemie", "date": "1979", "authors": "Yang C, Kratzin H, Gotz H, Hilschmann N", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "reference": [ { "type": "PubMed", "id": "393607", "url": "https://glygen.org/publication/PubMed/393607" } ] }, { "title": "Kinetics of hemoprotein reduction and interprotein heme transfer.", "journal": "Biochemistry", "date": "1985", "authors": "Pasternack RF, Gibbs EJ, Mauk AG, Reid LS, Wong NM, Kurokawa K, Hashim M, Muller-Eberhard U", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "4074707", "url": "https://glygen.org/publication/PubMed/4074707" } ] }, { "title": "Investigations on the oligosaccharide units of an A myeloma globulin.", "journal": "The Biochemical journal", "date": "1968", "authors": "Dawson G, Clamp JR", "evidence": [ { "database": "GlyConnect", "id": "227", "url": "https://glyconnect.expasy.org/browser/proteins/227" } ], "reference": [ { "type": "PubMed", "id": "4172099", "url": "https://glygen.org/publication/PubMed/4172099" } ] }, { "title": "Some spectral properties of the human hemoglobin-haptoglobin complex.", "journal": "Biochemistry", "date": "1971", "authors": "Hamaguchi H, Isomoto A, Miyake Y, Nakajima H", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "4327491", "url": "https://glygen.org/publication/PubMed/4327491" } ] }, { "title": "Structure of the carbohydrate units of IgA1 immunoglobulin. II. Structure of the O-glycosidically linked oligosaccharide units.", "journal": "The Journal of biological chemistry", "date": "1974", "authors": "Baenziger J, Kornfeld S", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876#ptm_processing" }, { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" }, { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "4373463", "url": "https://glygen.org/publication/PubMed/4373463" } ] }, { "title": "Structure of the carbohydrate units of IgA1 immunoglobulin. I. Composition, glycopeptide isolation, and structure of the asparagine-linked oligosaccharide units.", "journal": "The Journal of biological chemistry", "date": "1974", "authors": "Baenziger J, Kornfeld S", "evidence": [ { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "4436308", "url": "https://glygen.org/publication/PubMed/4436308" } ] }, { "title": "Human plasma protein C: isolation, characterization, and mechanism of activation by alpha-thrombin.", "journal": "The Journal of clinical investigation", "date": "1979", "authors": "Kisiel W", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "468991", "url": "https://glygen.org/publication/PubMed/468991" } ] }, { "title": "Haem transport to the liver by haemopexin. Receptor-mediated uptake with recycling of the protein.", "journal": "The Biochemical journal", "date": "1979", "authors": "Smith A, Morgan WT", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "496916", "url": "https://glygen.org/publication/PubMed/496916" } ] }, { "title": "Studies on the structures of haptoglobin 1-1 and hemoglobin in the haptoglobin-hemoglobin complex.", "journal": "Biochemical and biophysical research communications", "date": "1971", "authors": "Waks M, Kahn PC, Beychok S", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "5135507", "url": "https://glygen.org/publication/PubMed/5135507" } ] }, { "title": "Hemopexin-mediated heme uptake by liver. Characterization of the interaction of heme-hemopexin with isolated rabbit liver plasma membranes.", "journal": "The Journal of biological chemistry", "date": "1984", "authors": "Smith A, Morgan WT", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "6480598", "url": "https://glygen.org/publication/PubMed/6480598" } ] }, { "title": "Hemin binding to serum proteins and the catalysis of interprotein transfer.", "journal": "Biochemistry", "date": "1983", "authors": "Pasternack RF, Gibbs EJ, Hoeflin E, Kosar WP, Kubera G, Skowronek CA, Wong NM, Muller-Eberhard U", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "6849882", "url": "https://glygen.org/publication/PubMed/6849882" } ] }, { "title": "Heterogeneity of the glycans O-glycosidically linked to the hinge region of secretory immunoglobulins from human milk.", "journal": "European journal of biochemistry", "date": "1981", "authors": "Pierce-Cretel A, Pamblanco M, Strecker G, Montreuil J, Spik G", "evidence": [ { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "7215351", "url": "https://glygen.org/publication/PubMed/7215351" } ] }, { "title": "Haptoglobin-hemoglobin complex. Subunit interaction probed by cross-linking.", "journal": "The Journal of biological chemistry", "date": "1981", "authors": "Greer J, Liao WD, Brown WE", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "7263686", "url": "https://glygen.org/publication/PubMed/7263686" } ] }, { "title": "Hemopexin-mediated transport of heme into isolated rat hepatocytes.", "journal": "The Journal of biological chemistry", "date": "1981", "authors": "Smith A, Morgan WT", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "7287740", "url": "https://glygen.org/publication/PubMed/7287740" } ] }, { "title": "Haemoglobin binding with haptoglobin. Unequivocal demonstration that the beta-chains of human haemoglobin bind to haptoglobin.", "journal": "The Biochemical journal", "date": "1980", "authors": "Kazim AL, Atassi MZ", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "7378053", "url": "https://glygen.org/publication/PubMed/7378053" } ] }, { "title": "Location of a novel type of interpolypeptide chain linkage in the human protein HC-IgA complex (HC-IgA) and identification of a heterogeneous chromophore associated with the complex.", "journal": "The Journal of biological chemistry", "date": "1994", "authors": "Calero M, Escribano J, Grubb A, Mendez E", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "reference": [ { "type": "PubMed", "id": "7506257", "url": "https://glygen.org/publication/PubMed/7506257" } ] }, { "title": "Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains.", "journal": "Nature", "date": "1994", "authors": "Graves BJ, Crowther RL, Chandran C, Rumberger JM, Li S, Huang KS, Presky DH, Familletti PC, Wolitzky BA, Burns DK", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "7509040", "url": "https://glygen.org/publication/PubMed/7509040" } ] }, { "title": "The P-selectin glycoprotein ligand from human neutrophils displays sialylated, fucosylated, O-linked poly-N-acetyllactosamine.", "journal": "The Journal of biological chemistry", "date": "1994", "authors": "Moore KL, Eaton SF, Lyons DE, Lichenstein HS, Cummings RD, McEver RP", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "7521878", "url": "https://glygen.org/publication/PubMed/7521878" } ] }, { "title": "Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule.", "journal": "The Journal of cell biology", "date": "1994", "authors": "Litvinov SV, Velders MP, Bakker HA, Fleuren GJ, Warnaar SO", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "8163559", "url": "https://glygen.org/publication/PubMed/8163559" } ] }, { "title": "The surrogate light chain in B-cell development.", "journal": "Immunology today", "date": "1993", "authors": "Melchers F, Karasuyama H, Haasner D, Bauer S, Kudo A, Sakaguchi N, Jameson B, Rolink A", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "8166770", "url": "https://glygen.org/publication/PubMed/8166770" } ] }, { "title": "The alpha v beta 1 integrin functions as a fibronectin receptor but does not support fibronectin matrix assembly and cell migration on fibronectin.", "journal": "The Journal of cell biology", "date": "1993", "authors": "Zhang Z, Morla AO, Vuori K, Bauer JS, Juliano RL, Ruoslahti E", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "8314844", "url": "https://glygen.org/publication/PubMed/8314844" } ] }, { "title": "In vivo fate of hemopexin and heme-hemopexin complexes in the rat.", "journal": "Archives of biochemistry and biophysics", "date": "1993", "authors": "Potter D, Chroneos ZC, Baynes JW, Sinclair PR, Gorman N, Liem HH, Muller-Eberhard U, Thorpe SR", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "8424694", "url": "https://glygen.org/publication/PubMed/8424694" } ] }, { "title": "Role of hemopexin in protection of low-density lipoprotein against hemoglobin-induced oxidation.", "journal": "Biochemistry", "date": "1996", "authors": "Miller YI, Smith A, Morgan WT, Shaklai N", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "8855948", "url": "https://glygen.org/publication/PubMed/8855948" } ] }, { "title": "An endothelial receptor for oxidized low-density lipoprotein.", "journal": "Nature", "date": "1997", "authors": "Sawamura T, Kume N, Aoyama T, Moriwaki H, Hoshikawa H, Aiba Y, Tanaka T, Miwa S, Katsura Y, Kita T, Masaki T", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "9052782", "url": "https://glygen.org/publication/PubMed/9052782" } ] }, { "title": "Differential recognition of members of the carcinoembryonic antigen family by Opa variants of Neisseria gonorrhoeae.", "journal": "Infection and immunity", "date": "1997", "authors": "Bos MP, Grunert F, Belland RJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "9169774", "url": "https://glygen.org/publication/PubMed/9169774" } ] }, { "title": "An antagonist decoy receptor and a death domain-containing receptor for TRAIL.", "journal": "Science (New York, N.Y.)", "date": "1997", "authors": "Pan G, Ni J, Wei YF, Yu G, Gentz R, Dixit VM", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "9242610", "url": "https://glygen.org/publication/PubMed/9242610" } ] }, { "title": "A novel association of Fc receptor gamma-chain with glycoprotein VI and their co-expression as a collagen receptor in human platelets.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Tsuji M, Ezumi Y, Arai M, Takayama H", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "9295288", "url": "https://glygen.org/publication/PubMed/9295288" } ] }, { "title": "Epithelial cell adhesion molecule (Ep-CAM) modulates cell-cell interactions mediated by classic cadherins.", "journal": "The Journal of cell biology", "date": "1997", "authors": "Litvinov SV, Balzar M, Winter MJ, Bakker HA, Briaire-de Bruijn IH, Prins F, Fleuren GJ, Warnaar SO", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "9382878", "url": "https://glygen.org/publication/PubMed/9382878" } ] }, { "title": "The glycosylation and structure of human serum IgA1, Fab, and Fc regions and the role of N-glycosylation on Fcalpha receptor interactions.", "journal": "The Journal of biological chemistry", "date": "1998", "authors": "Mattu TS, Pleass RJ, Willis AC, Kilian M, Wormald MR, Lellouch AC, Rudd PM, Woof JM, Dwek RA", "evidence": [ { "database": "GlyGen", "id": "GLY_000481", "url": "https://data.glygen.org/GLY_000481" }, { "database": "GlyConnect", "id": "230", "url": "https://glyconnect.expasy.org/browser/proteins/230" } ], "reference": [ { "type": "PubMed", "id": "9442070", "url": "https://glygen.org/publication/PubMed/9442070" } ] }, { "title": "Identification of the lectin-like receptor for oxidized low-density lipoprotein in human macrophages and its potential role as a scavenger receptor.", "journal": "The Biochemical journal", "date": "1998", "authors": "Yoshida H, Kondratenko N, Green S, Steinberg D, Quehenberger O", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "9693095", "url": "https://glygen.org/publication/PubMed/9693095" } ] }, { "title": "Transfer of heme from heme-albumin to hemopexin.", "journal": "Biochimica et biophysica acta", "date": "1976", "authors": "Morgan WT, Liem HH, Sutor RP, Muller-Ebergard U", "evidence": [ { "database": "Reactome", "id": "R-HSA-2168880", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880" } ], "reference": [ { "type": "PubMed", "id": "971416", "url": "https://glygen.org/publication/PubMed/971416" } ] }, { "title": "Ligand specificity of LOX-1, a novel endothelial receptor for oxidized low density lipoprotein.", "journal": "Arteriosclerosis, thrombosis, and vascular biology", "date": "1998", "authors": "Moriwaki H, Kume N, Sawamura T, Aoyama T, Hoshikawa H, Ochi H, Nishi E, Masaki T, Kita T", "evidence": [ { "database": "Reactome", "id": "R-HSA-202733", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733" } ], "reference": [ { "type": "PubMed", "id": "9763524", "url": "https://glygen.org/publication/PubMed/9763524" } ] } ], "pathway": [ { "id": "R-HSA-202733", "name": "Cell surface interactions at the vascular wall", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-202733", "resource": "Reactome", "description": "Cell surface interactions at the vascular wall" }, { "id": "R-HSA-2168880", "name": "Scavenging of heme from plasma", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2168880", "resource": "Reactome", "description": "Scavenging of heme from plasma" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0A6YXW6-1", "protein_name": "Immunoglobulin heavy constant alpha", "gene_name": "Igha", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XSARNPTIYPLTLPRALSSDPVIIGCLIHDYFPSGTMNVTWGKSGKDITTVNFPPALASGGGYTMSSQLTLPAVECPEGESVKCSVQHDSNAVQELDVKCSGPPPPCPPCPPSCHPSLSLQRPALEDLLLGSDASLTCTLNGLRNPEGAVFTWEPSTGKDAVQKKAVQNSCGCYSVSSVLPGCAERWNSGASFKCTVTHPESDTLTGTIAKITVNTFPPQVHLLPPPSEELALNELVSLTCLVRAFNPKEVLVRWLHGNEELSPESYLVFEPLKEPGEGATTYLVTSVLRVSAELWKQGDQYSCMVGHEALPMNFTQKTIDRLSERQEPLSYVLLDQSEDILEEEAPGASLWPTTVTFLTLFLLSLFYSTALTVTTVRGPFGSKEVPQY", "length": 389 }, "evidence": [ { "id": "HGNC:5478", "url": "https://alliancegenome.org/gene/HGNC:5478#orthology", "database": "AGR" }, { "id": "MGI:96444", "url": "https://alliancegenome.org/gene/MGI:96444#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01877-2", "protein_name": "Immunoglobulin heavy constant alpha 2", "gene_name": "IGHA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "ASPTSPKVFPLSLDSTPQDGNVVVACLVQGFFPQEPLSVTWSESGQNVTARNFPPSQDASGDLYTTSSQLTLPATQCPDGKSVTCHVKHYTNSSQDVTVPCRVPPPPPCCHPRLSLHRPALEDLLLGSEANLTCTLTGLRDASGATFTWTPSSGKSAVQGPPERDLCGCYSVSSVLPGCAQPWNHGETFTCTAAHPELKTPLTANITKSGNTFRPEVHLLPPPSEELALNELVTLTCLARGFSPKDVLVRWLQGSQELPREKYLTWASRQEPSQGTTTYAVTSILRVAAEDWKKGETFSCMVGHEALPLAFTQKTIDRMAGSCCVADWQMPPPYVVLDLPQETLEEETPGANLWPTTITFLTLFLLSLFYSTALTVTSVRGPSGKREGPQY", "length": 391 }, "evidence": [ { "id": "MGI:96444", "url": "https://alliancegenome.org/gene/MGI:96444#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 11, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" }, { "name": "blood microparticle", "id": "GO:0072562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072562", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" }, { "name": "immunoglobulin complex, circulating", "id": "GO:0042571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042571", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" }, { "name": "monomeric IgA immunoglobulin complex", "id": "GO:0071748", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071748", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" }, { "name": "secretory IgA immunoglobulin complex", "id": "GO:0071751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071751", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" }, { "name": "secretory dimeric IgA immunoglobulin complex", "id": "GO:0071752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071752", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" }, { "name": "IgG immunoglobulin complex", "id": "GO:0071735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071735", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" }, { "name": "IgA immunoglobulin complex", "id": "GO:0071745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071745", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" }, { "name": "antibacterial humoral response", "id": "GO:0019731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019731", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" }, { "name": "B cell receptor signaling pathway", "id": "GO:0050853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" }, { "name": "glomerular filtration", "id": "GO:0003094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003094", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" }, { "name": "complement activation, classical pathway", "id": "GO:0006958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006958", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" }, { "name": "positive regulation of respiratory burst", "id": "GO:0060267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060267", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "antigen binding", "id": "GO:0003823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003823", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" } ], "pmid": "" } ] } ] }, "pro_annotation": [ { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 1 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G00912UN. [PRO:DNx, PMID:22171320, PMID:24766575, PMID:24841998, PMID:30659065]", "evidence": [ { "id": "PR:000052334", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052334" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 2 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G01650EU. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G01650EU. [PRO:DNx, PMID:22171320, PMID:24766575, PMID:24841998, PMID:30659065]", "evidence": [ { "id": "PR:000052335", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052335" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 3 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G02815KT. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G02815KT. [PRO:DNx, PMID:22171320, PMID:24766575, PMID:24841998, PMID:30659065]", "evidence": [ { "id": "PR:000052336", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052336" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 4 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G08293MJ. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G08293MJ. [PRO:DNx, PMID:30659065]", "evidence": [ { "id": "PR:000052337", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052337" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 5 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G10486CT. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G10486CT. [PRO:DNx, PMID:22171320, PMID:24766575, PMID:24841998, PMID:30659065]", "evidence": [ { "id": "PR:000052338", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052338" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 6 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan structure is represented by GlyTouCan:G22140GZ. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G22140GZ. [PRO:DNx, PMID:19838169]", "evidence": [ { "id": "PR:000052339", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052339" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 7 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G27947YN. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G27947YN. [PRO:DNx, PMID:22171320, PMID:24766575, PMID:24841998]", "evidence": [ { "id": "PR:000052340", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052340" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 8 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G31852PQ. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G31852PQ. [PRO:DNx, PMID:22171320, PMID:24766575, PMID:24841998]", "evidence": [ { "id": "PR:000052341", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052341" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 9 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G36670VW. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G36670VW. [PRO:DNx, PMID:30659065]", "evidence": [ { "id": "PR:000052342", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052342" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 10 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G37399XV. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G37399XV. [PRO:DNx, PMID:22171320, PMID:24766575, PMID:24841998, PMID:30659065]", "evidence": [ { "id": "PR:000052343", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052343" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 11 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G40926MX. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G40926MX. [PRO:DNx, PMID:22171320, PMID:24766575, PMID:24841998]", "evidence": [ { "id": "PR:000052344", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052344" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 12 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G45504EY. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G45504EY. [PRO:DNx, PMID:22171320, PMID:24766575, PMID:24841998, PMID:30659065]", "evidence": [ { "id": "PR:000052345", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052345" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 13 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G49955PK. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G49955PK. [PRO:DNx, PMID:22171320, PMID:24766575, PMID:24841998, PMID:30659065]", "evidence": [ { "id": "PR:000052346", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052346" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 14 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G58001LT. [PRO:DNx, PMID:22171320, PMID:24766575, PMID:24841998]", "evidence": [ { "id": "PR:000052347", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052347" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 15 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G59626AS. [PRO:DNx, PMID:22171320, PMID:24766575, PMID:24841998, PMID:29671580, PMID:30659065]", "evidence": [ { "id": "PR:000052348", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052348" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 16 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G62765YT. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G62765YT. [PRO:DNx, PMID:22171320, PMID:24766575, PMID:24841998]", "evidence": [ { "id": "PR:000052349", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052349" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 17 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G65184UU. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G65184UU. [PRO:DNx, PMID:30659065]", "evidence": [ { "id": "PR:000052350", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052350" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 18 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G65681LR. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G65681LR. [PRO:DNx, PMID:30659065]", "evidence": [ { "id": "PR:000052351", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052351" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 19 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G72790NZ. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G72790NZ. [PRO:DNx, PMID:30659065]", "evidence": [ { "id": "PR:000052352", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052352" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 20 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G83646BJ. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G83646BJ. [PRO:DNx, PMID:22171320, PMID:24766575, PMID:24841998, PMID:30659065]", "evidence": [ { "id": "PR:000052353", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052353" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 21 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G86182NS. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G86182NS. [PRO:DNx, PMID:22171320, PMID:24766575, PMID:24841998, PMID:30659065]", "evidence": [ { "id": "PR:000052354", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052354" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 22 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G88374WZ. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G88374WZ. [PRO:DNx, PMID:22171320, PMID:24766575, PMID:24841998]", "evidence": [ { "id": "PR:000052355", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052355" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 23 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-144 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G95865ZB. Example: UniProtKB:P01876-1, Asn-144, MOD:00160~GNO:G95865ZB. [PRO:DNx, PMID:30659065]", "evidence": [ { "id": "PR:000052356", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052356" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 24 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G00912UN. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052357", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052357" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 25 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G01650EU. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G01650EU. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052358", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052358" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 26 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G02815KT. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G02815KT. [PRO:DNx, PMID:29671580, PMID:29741879, PMID:30659065]", "evidence": [ { "id": "PR:000052359", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052359" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 27 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G05428EU. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G05428EU. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052360", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052360" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 28 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G06247RL. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G06247RL. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052361", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052361" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 29 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G08293MJ. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G08293MJ. [PRO:DNx, PMID:29671580, PMID:29741879, PMID:30659065]", "evidence": [ { "id": "PR:000052362", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052362" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 30 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G12580WI. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G12580WI. [PRO:DNx, PMID:29671580, PMID:29741879, PMID:30659065]", "evidence": [ { "id": "PR:000052363", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052363" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 31 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G27947YN. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G27947YN. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052364", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052364" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 32 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G36670VW. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G36670VW. [PRO:DNx, PMID:24841998, PMID:29671580, PMID:29741879, PMID:30659065]", "evidence": [ { "id": "PR:000052365", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052365" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 33 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G40926MX. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G40926MX. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052366", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052366" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 34 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G41044JW. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G41044JW. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052367", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052367" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 35 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G41247ZX. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G41247ZX. [PRO:DNx, PMID:29671580, PMID:29741879, PMID:30659065]", "evidence": [ { "id": "PR:000052368", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052368" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 36 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G53434XO. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052369", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052369" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 37 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G54417MJ. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G54417MJ. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052370", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052370" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 38 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G55382TU. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G55382TU. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052371", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052371" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 39 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G57776ZU. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G57776ZU. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052372", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052372" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 40 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G59626AS. [PRO:DNx, PMID:29671580, PMID:29741879, PMID:30659065]", "evidence": [ { "id": "PR:000052373", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052373" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 41 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G65184UU. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G65184UU. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052374", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052374" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 42 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G65681LR. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G65681LR. [PRO:DNx, PMID:29741879, PMID:30659065]", "evidence": [ { "id": "PR:000052375", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052375" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 43 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G68318VE. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G68318VE. [PRO:DNx, PMID:29671580, PMID:29741879, PMID:30659065]", "evidence": [ { "id": "PR:000052376", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052376" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 44 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G72790NZ. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G72790NZ. [PRO:DNx, PMID:29741879, PMID:30659065]", "evidence": [ { "id": "PR:000052377", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052377" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 45 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G83555HU. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G83555HU. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052378", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052378" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 46 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G83646BJ. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G83646BJ. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052379", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052379" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 47 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G85144OK. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G85144OK. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052380", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052380" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 48 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G85740DB. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G85740DB. [PRO:DNx, PMID:29671580, PMID:29741879, PMID:30659065]", "evidence": [ { "id": "PR:000052381", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052381" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 49 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G86182NS. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G86182NS. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052382", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052382" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 50 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G86752LQ. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G86752LQ. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052383", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052383" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 51 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G88374WZ. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G88374WZ. [PRO:DNx, PMID:29671580, PMID:29741879, PMID:30659065]", "evidence": [ { "id": "PR:000052384", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052384" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 52 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G94917XT. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G94917XT. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052385", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052385" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 53 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G98596OT. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G98596OT. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052386", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052386" } ] }, { "name": "immunoglobulin heavy constant alpha 1 N-glycosylated 54 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been N-glycosylated at the residue equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G99679NM. Example: UniProtKB:P01876-1, Asn-340, MOD:00160~GNO:G99679NM. [PRO:DNx, PMID:29671580]", "evidence": [ { "id": "PR:000052387", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052387" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 1 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-111 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G27391WQ. Example: UniProtKB:P01876-1, Ser-111, MOD:00002~GNO:G27391WQ. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052388", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052388" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 2 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-111 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G29063QY. Example: UniProtKB:P01876-1, Ser-111, MOD:00002~GNO:G29063QY. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052389", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052389" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 3 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-111 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P01876-1, Ser-111, MOD:00002~GNO:G29068FM. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052390", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052390" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 4 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-111 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G36670VW. Example: UniProtKB:P01876-1, Ser-111, MOD:00002~GNO:G36670VW. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052391", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052391" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 5 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-111 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01876-1, Ser-111, MOD:00002~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052392", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052392" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 6 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-111 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P01876-1, Ser-111, MOD:00002~GNO:G53434XO. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052393", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052393" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 7 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-111 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P01876-1, Ser-111, MOD:00002~GNO:G58001LT. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052394", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052394" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 8 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-111 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G73004SD. Example: UniProtKB:P01876-1, Ser-111, MOD:00002~GNO:G73004SD. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052395", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052395" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 9 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-111 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G88713AC. Example: UniProtKB:P01876-1, Ser-111, MOD:00002~GNO:G88713AC. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052396", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052396" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 10 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-113 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G08293MJ. Example: UniProtKB:P01876-1, Ser-113, MOD:00002~GNO:G08293MJ. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052397", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052397" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 11 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-113 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G27391WQ. Example: UniProtKB:P01876-1, Ser-113, MOD:00002~GNO:G27391WQ. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052398", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052398" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 12 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-113 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P01876-1, Ser-113, MOD:00002~GNO:G29068FM. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052399", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052399" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 13 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-113 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01876-1, Ser-113, MOD:00002~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052400", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052400" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 14 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-113 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P01876-1, Ser-113, MOD:00002~GNO:G53434XO. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052401", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052401" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 15 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-113 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P01876-1, Ser-113, MOD:00002~GNO:G58001LT. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052402", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052402" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 16 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-113 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G73004SD. Example: UniProtKB:P01876-1, Ser-113, MOD:00002~GNO:G73004SD. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052403", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052403" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 17 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-113 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G88713AC. Example: UniProtKB:P01876-1, Ser-113, MOD:00002~GNO:G88713AC. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052404", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052404" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 18 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Ser-119 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01876-1, Ser-119, MOD:00002~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052405", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052405" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 19 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Thr-114 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G27391WQ. Example: UniProtKB:P01876-1, Thr-114, MOD:00005~GNO:G27391WQ. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052406", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052406" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 20 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Thr-114 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P01876-1, Thr-114, MOD:00005~GNO:G29068FM. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052407", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052407" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 21 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Thr-114 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01876-1, Thr-114, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052408", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052408" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 22 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Thr-114 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P01876-1, Thr-114, MOD:00005~GNO:G58001LT. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052409", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052409" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 23 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Thr-117 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P01876-1, Thr-117, MOD:00005~GNO:G29068FM. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052410", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052410" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 24 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Thr-117 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01876-1, Thr-117, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052411", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052411" } ] }, { "name": "immunoglobulin heavy constant alpha 1 O-glycosylated 25 (human)", "definition": "An immunoglobulin heavy constant alpha 1 (human) that has been O-glycosylated at the residue equivalent to Thr-117 of the amino acid sequence represented by UniProtKB:P01876-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P01876-1, Thr-117, MOD:00005~GNO:G58001LT. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000052412", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000052412" } ] } ], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [ { "annotation": "3-Hydroxykynurenine, an oxidized tryptophan metabolite that is common in biological fluids, reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" }, { "database": "PubMed", "id": "7506257", "url": "https://glygen.org/publication/PubMed/7506257" } ] }, { "annotation": "N- and O-glycosylated. N-glycan at Asn-144: Hex5HexNAc4.", "evidence": [ { "database": "UniProtKB", "id": "P01876", "url": "https://www.uniprot.org/uniprot/P01876" }, { "database": "PubMed", "id": "19838169", "url": "https://glygen.org/publication/PubMed/19838169" }, { "database": "PubMed", "id": "19139490", "url": "https://glygen.org/publication/PubMed/19139490" }, { "database": "PubMed", "id": "15084671", "url": "https://glygen.org/publication/PubMed/15084671" }, { "database": "PubMed", "id": "22171320", "url": "https://glygen.org/publication/PubMed/22171320" } ] } ], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P01876-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 398, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P01876-F1.pdb" }, { "pdb_id": "3chn", "pdb_chain": "a/b/c/d", "start_pos": 2, "end_pos": 353, "overlap": "1.0", "method": "X-Ray_Crystallography", "type": "experimental", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/3chn.pdb" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [ 144 ], "o_linked_sites": [ 89, 105, 106, 109, 111, 113, 114, 117, 119, 121, 225, 268 ], "snv_sites": [ 45, 105, 106, 117, 144, 146, 169, 218, 234, 274, 299, 333 ], "glycation_sites": [], "phosphorylation_sites": [ 201, 328 ], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 229 }, { "field": "total_sites", "count": 14 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 12 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 11 }, { "field": "n_linked_glycans", "count": 67 }, { "field": "o_linked_glycans", "count": 58 }, { "field": "exact_sites", "count": 13 }, { "field": "exact_o_linked_sites", "count": 12 }, { "field": "exact_o_linked_glycan_sites", "count": 11 }, { "field": "exact_o_linked_glycans", "count": 58 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "exact_n_linked_glycan_sites", "count": 1 }, { "field": "exact_n_linked_glycans", "count": 67 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 48 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 44 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 10 }, { "field": "total_sites", "count": 10 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 9 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 10 }, { "field": "exact_o_linked_sites", "count": 9 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 217 }, { "field": "total_sites", "count": 13 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 11 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 11 }, { "field": "n_linked_glycans", "count": 67 }, { "field": "o_linked_glycans", "count": 58 }, { "field": "exact_sites", "count": 12 }, { "field": "exact_o_linked_sites", "count": 11 }, { "field": "exact_o_linked_glycan_sites", "count": 11 }, { "field": "exact_o_linked_glycans", "count": 58 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "exact_n_linked_glycan_sites", "count": 1 }, { "field": "exact_n_linked_glycans", "count": 67 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 48 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 44 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "prediction_tool", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 12 }, { "field": "total_sites", "count": 12 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 11 }, { "field": "total_sites", "count": 11 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 142 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }