{
    "uniprot_canonical_ac": "A0A0R4ILJ8-1",
    "uniprot_ac": "A0A0R4ILJ8",
    "uniprot_id": "A0A0R4ILJ8_DANRE",
    "mass": {
        "chemical_mass": 18420.0,
        "monoisotopic_mass": 18420.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "glrx2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8",
            "id": "A0A0R4ILJ8"
        },
        {
            "name": "zgc:92698",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8",
            "id": "A0A0R4ILJ8"
        }
    ],
    "protein_names": [
        {
            "name": "Glutaredoxin-2, mitochondrial",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprotkb/A0A0R4ILJ8/entry#names_and_taxonomy",
            "id": "A0A0R4ILJ8"
        }
    ],
    "function": [
        {
            "annotation": "Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0R4ILJ8",
                    "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "ARBA00037470",
                    "url": "https://www.uniprot.org/uniprot/ARBA00037470#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q6DH06",
                    "url": "https://www.uniprot.org/uniprot/Q6DH06#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "A0A8M2B8M4",
                    "url": "https://www.uniprot.org/uniprot/A0A8M2B8M4#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "A0A0R4IXU6",
                    "url": "https://www.uniprot.org/uniprot/A0A0R4IXU6#function"
                }
            ]
        },
        {
            "annotation": "Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0R4ILJ8",
                    "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "ARBA00002549",
                    "url": "https://www.uniprot.org/uniprot/ARBA00002549#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q6DH06",
                    "url": "https://www.uniprot.org/uniprot/Q6DH06#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "A0A8M2B8M4",
                    "url": "https://www.uniprot.org/uniprot/A0A8M2B8M4#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "A0A0R4IXU6",
                    "url": "https://www.uniprot.org/uniprot/A0A0R4IXU6#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Danio rerio",
            "taxid": 7955,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0R4ILJ8",
                    "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8"
                }
            ],
            "common_name": "Zebrafish",
            "glygen_name": "Zebrafish",
            "reference_species": "Danio rerio [7955]"
        }
    ],
    "gene": [
        {
            "name": "glrx2",
            "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8",
            "locus": {}
        }
    ],
    "crossref": [
        {
            "id": "ZFIN:ZDB-GENE-040718-101",
            "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-101",
            "database": "AGR",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "ENSDARG00000100944",
            "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000100944",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd03419",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03419",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "436677",
            "url": "https://www.ncbi.nlm.nih.gov/gene/436677",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR002109",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002109",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR011767",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011767",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR011899",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011899",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR014025",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR014025",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036249",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dre:436677",
            "url": "https://www.genome.jp/dbget-bin/www_bget?dre:436677",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "INGNCVG",
            "url": "https://omabrowser.org/oma/group/INGNCVG/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "A0A0R4ILJ8",
            "url": "https://www.orthodb.org/?gene=A0A0R4ILJ8",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "A0A0R4IXU6",
            "url": "https://www.orthodb.org/?gene=A0A0R4IXU6",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "Q6DH06",
            "url": "https://www.orthodb.org/?gene=Q6DH06",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR46679:SF1",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46679:SF1",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "3UIW",
            "url": "https://www.rcsb.org/structure/3UIW",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "PF00462",
            "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00462",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "XP_005161790",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161790",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0R4ILJ8",
            "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0R4ILJ8-1",
            "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0R4IXU6",
            "url": "https://www.uniprot.org/uniprot/A0A0R4IXU6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0R4IXU6-1",
            "url": "https://www.uniprot.org/uniprot/A0A0R4IXU6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8M2B8M4",
            "url": "https://www.uniprot.org/uniprot/A0A8M2B8M4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8M2B8M4-1",
            "url": "https://www.uniprot.org/uniprot/A0A8M2B8M4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q6DH06",
            "url": "https://www.uniprot.org/uniprot/Q6DH06",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q6DH06-1",
            "url": "https://www.uniprot.org/uniprot/Q6DH06-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "ZDB-GENE-040718-101",
            "url": "https://zfin.org/ZDB-GENE-040718-101",
            "database": "ZFIN",
            "categories": [
                "Protein",
                "Organism-specific"
            ]
        }
    ],
    "sequence": {
        "sequence": "MIDLNCQSNSLVSALTAFAFLVSSTCFFYRPVIITRMGNFSSSAPGLSSSACGQFVQDIVSSNCVVIFSKTTCPYCKMAKGVFNEIGATYKVVELDEHNDGRRLQETLAELTGARTVPRVFINGQCIGGGSDTKQLHQQGKLLPLIEQCRPCCLNMTPEGSGNSQNQPHQ",
        "length": 170,
        "header": "tr|A0A0R4ILJ8-1|A0A0R4ILJ8_DANRE Isoform 1 of Glutaredoxin-2, mitochondrial  OS=Danio rerio OX=7955 GN=glrx2 PE=1 SV=1 CANONICAL=A0A0R4ILJ8-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0R4ILJ8-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0R4ILJ8/entry#A0A0R4ILJ8-1",
            "sequence": {
                "sequence": "MIDLNCQSNSLVSALTAFAFLVSSTCFFYRPVIITRMGNFSSSAPGLSSSACGQFVQDIVSSNCVVIFSKTTCPYCKMAKGVFNEIGATYKVVELDEHNDGRRLQETLAELTGARTVPRVFINGQCIGGGSDTKQLHQQGKLLPLIEQCRPCCLNMTPEGSGNSQNQPHQ",
                "length": 170,
                "header": "tr|A0A0R4ILJ8-1|A0A0R4ILJ8_DANRE Isoform 1 of Glutaredoxin-2, mitochondrial  OS=Danio rerio OX=7955 GN=glrx2 PE=1 SV=1 CANONICAL=A0A0R4ILJ8-1"
            },
            "locus": {}
        },
        {
            "isoform_ac": "A0A0R4IXU6-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0R4ILJ8/entry#A0A0R4IXU6-1",
            "sequence": {
                "sequence": "MFTRGCFYKSRQAYQSLRMGNFSSSAPGLSSSACGQFVQDIVSSNCVVIFSKTTCPYCKMAKGVFNEIGATYKVVELDEHNDGRRLQETLAELTGARTVPRVFINGQCIGGGSDTKQLHQQGKLLPLIEQCRPCCLNMTPEGSGNSQNQPHQ",
                "length": 152,
                "header": "tr|A0A0R4IXU6-1|A0A0R4IXU6_DANRE Computationally mapped isoform of Glutaredoxin-2, mitochondrial  OS=Danio rerio OX=7955 GN=glrx2 PE=1 SV=1 CANONICAL=A0A0R4ILJ8-1"
            },
            "locus": {}
        },
        {
            "isoform_ac": "A0A8M2B8M4-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0R4ILJ8/entry#A0A8M2B8M4-1",
            "sequence": {
                "sequence": "MNIWQTREGRSLIRQINVVPVERMGNFSSSAPGLSSSACGQFVQDIVSSNCVVIFSKTTCPYCKMAKGVFNEIGATYKVVELDEHNDGRRLQETLAELTGARTVPRVFINGQCIGGGSDTKQLHQQGKLLPLIEQCRPCCLNMTPEGSGNSQNQPHQ",
                "length": 157,
                "header": "tr|A0A8M2B8M4-1|A0A8M2B8M4_DANRE Computationally mapped isoform of Glutaredoxin-2, mitochondrial  OS=Danio rerio OX=7955 GN=glrx2 PE=1 SV=1 CANONICAL=A0A0R4ILJ8-1"
            },
            "locus": {}
        },
        {
            "isoform_ac": "Q6DH06-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0R4ILJ8/entry#Q6DH06-1",
            "sequence": {
                "sequence": "MGNFSSSAPGLSSSACGQFVQDIVSSNCVVIFSKTTCPYCKMAKGVFNEIGATYKVVELDEHNDGRRLQETLAELTGARTVPRVFINGQCIGGGSDTKQLHQQGKLLPLIEQCRPCCLNMTPEGSGNSQNQPHQ",
                "length": 134,
                "header": "tr|Q6DH06-1|Q6DH06_DANRE Computationally mapped isoform of Glutaredoxin-2, mitochondrial  OS=Danio rerio OX=7955 GN=glrx2 PE=1 SV=1 CANONICAL=A0A0R4ILJ8-1"
            },
            "locus": {}
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "dre:436677",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/www_bget?dre:436677",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "A0A287A9I5-1",
            "protein_name": "Glutaredoxin-2, mitochondrial",
            "gene_name": "GLRX2",
            "tax_id": 9823,
            "organism": "Sus scrofa",
            "sequence": {
                "sequence": "MYWRRAALAGTRLVRRVSGSTGRFGGAPGASASGMGNHTSSSLGNTAAAPVNQIQETISNNCVVIFSKTSCSYCTMAKKLFHDMNVSYKVVELDLLEYGSQFQDALCTMTGDRTVPRIFVNGTFIGGAMDTHRLHQEGKLLPLVHQCYLKKSKRKEF",
                "length": 157
            },
            "evidence": [
                {
                    "id": "A0A0R4ILJ8",
                    "url": "https://omabrowser.org/oma/group/A0A0R4ILJ8/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Pig",
            "common_name": "Pig"
        },
        {
            "uniprot_canonical_ac": "P17695-1",
            "protein_name": "Glutaredoxin-2",
            "gene_name": "GRX2",
            "tax_id": 559292,
            "organism": "Saccharomyces cerevisiae S288C",
            "sequence": {
                "sequence": "METNFSFDSNLIVIIIITLFATRIIAKRFLSTPKMVSQETVAHVKDLIGQKEVFVAAKTYCPYCKATLSTLFQELNVPKSKALVLELDEMSNGSEIQDALEEISGQKTVPNVYINGKHIGGNSDLETLKKNGKLAEILKPVFQ",
                "length": 143
            },
            "evidence": [
                {
                    "id": "FB:FBgn0036820",
                    "url": "https://alliancegenome.org/gene/FB:FBgn0036820#orthology",
                    "database": "AGR"
                },
                {
                    "id": "SGD:S000002921",
                    "url": "https://alliancegenome.org/gene/SGD:S000002921#orthology",
                    "database": "AGR"
                },
                {
                    "id": "FB:FBgn0034658",
                    "url": "https://alliancegenome.org/gene/FB:FBgn0034658#orthology",
                    "database": "AGR"
                },
                {
                    "id": "MGI:1916617",
                    "url": "https://alliancegenome.org/gene/MGI:1916617#orthology",
                    "database": "AGR"
                },
                {
                    "id": "ZFIN:ZDB-GENE-040718-101",
                    "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-101#orthology",
                    "database": "AGR"
                },
                {
                    "id": "RGD:1307950",
                    "url": "https://alliancegenome.org/gene/RGD:1307950#orthology",
                    "database": "AGR"
                },
                {
                    "id": "HGNC:16065",
                    "url": "https://alliancegenome.org/gene/HGNC:16065#orthology",
                    "database": "AGR"
                }
            ],
            "glygen_name": "Yeast",
            "common_name": "Baker's yeast"
        },
        {
            "uniprot_canonical_ac": "P25373-1",
            "protein_name": "Glutaredoxin-1",
            "gene_name": "GRX1",
            "tax_id": 559292,
            "organism": "Saccharomyces cerevisiae S288C",
            "sequence": {
                "sequence": "MVSQETIKHVKDLIAENEIFVASKTYCPYCHAALNTLFEKLKVPRSKVLVLQLNDMKEGADIQAALYEINGQRTVPNIYINGKHIGGNDDLQELRETGELEELLEPILAN",
                "length": 110
            },
            "evidence": [
                {
                    "id": "FB:FBgn0036820",
                    "url": "https://alliancegenome.org/gene/FB:FBgn0036820#orthology",
                    "database": "AGR"
                },
                {
                    "id": "FB:FBgn0034658",
                    "url": "https://alliancegenome.org/gene/FB:FBgn0034658#orthology",
                    "database": "AGR"
                },
                {
                    "id": "SGD:S000000540",
                    "url": "https://alliancegenome.org/gene/SGD:S000000540#orthology",
                    "database": "AGR"
                },
                {
                    "id": "MGI:1916617",
                    "url": "https://alliancegenome.org/gene/MGI:1916617#orthology",
                    "database": "AGR"
                },
                {
                    "id": "ZFIN:ZDB-GENE-040718-101",
                    "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-101#orthology",
                    "database": "AGR"
                },
                {
                    "id": "RGD:1307950",
                    "url": "https://alliancegenome.org/gene/RGD:1307950#orthology",
                    "database": "AGR"
                },
                {
                    "id": "HGNC:16065",
                    "url": "https://alliancegenome.org/gene/HGNC:16065#orthology",
                    "database": "AGR"
                }
            ],
            "glygen_name": "Yeast",
            "common_name": "Baker's yeast"
        },
        {
            "uniprot_canonical_ac": "P38068-1",
            "protein_name": "Monothiol glutaredoxin-7",
            "gene_name": "GRX7",
            "tax_id": 559292,
            "organism": "Saccharomyces cerevisiae S288C",
            "sequence": {
                "sequence": "MAIVINKRNVRVLVITNLLLIVVFFVLRNSNASVNESITTHHPDSLVTFDNSGNAPGTHQSVHDTVNTQDKEAEEVDKNSGDAEFDAAAEYNKIMEQSPMIVFSKTGCPYSKKLKALLTNSYTFSPSYYVVELDRHEHTKELQDQIEKVTGRRTVPNVIIGGTSRGGYTEIAELHKNDELLDSFKKWSDGAFTVKANSQSESA",
                "length": 203
            },
            "evidence": [
                {
                    "id": "ZFIN:ZDB-GENE-040718-101",
                    "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-101#orthology",
                    "database": "AGR"
                },
                {
                    "id": "SGD:S000000218",
                    "url": "https://alliancegenome.org/gene/SGD:S000000218#orthology",
                    "database": "AGR"
                }
            ],
            "glygen_name": "Yeast",
            "common_name": "Baker's yeast"
        },
        {
            "uniprot_canonical_ac": "Q12438-1",
            "protein_name": "Monothiol glutaredoxin-6",
            "gene_name": "GRX6",
            "tax_id": 559292,
            "organism": "Saccharomyces cerevisiae S288C",
            "sequence": {
                "sequence": "MIPSNKRNARILSITTLLLLLVFFVAQNANFLTVEIKEETSKAFSTNMDNMAGGSSREYAAMPTSTTNKGSSEVDEEINEIKQKVGLQQPIASVDDSLSAIKNDKGSRITKAFNVQKEYSLILDLSPIIIFSKSTCSYSKGMKELLENEYQFIPNYYIIELDKHGHGEELQEYIKLVTGRGTVPNLLVNGVSRGGNEEIKKLHTQGKLLESLQVWSDGKFSVEQREKPSNN",
                "length": 231
            },
            "evidence": [
                {
                    "id": "SGD:S000002168",
                    "url": "https://alliancegenome.org/gene/SGD:S000002168#orthology",
                    "database": "AGR"
                },
                {
                    "id": "ZFIN:ZDB-GENE-040718-101",
                    "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-101#orthology",
                    "database": "AGR"
                }
            ],
            "glygen_name": "Yeast",
            "common_name": "Baker's yeast"
        },
        {
            "uniprot_canonical_ac": "Q32L67-1",
            "protein_name": "Glutaredoxin-2, mitochondrial",
            "gene_name": "GLRX2",
            "tax_id": 9913,
            "organism": "Bos taurus",
            "sequence": {
                "sequence": "MYWRRAALVGTRLIPVRSSSAGRLEGPAGISGSGMGNSTSSSLGNAATAPVNQIQETISNNCVVIFSKTSCSYCTMAKNLFHDMNVNYKVVELDMLEYGSQFQDALHKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQCHLKNSKREEL",
                "length": 157
            },
            "evidence": [
                {
                    "id": "A0A0R4ILJ8",
                    "url": "https://omabrowser.org/oma/group/A0A0R4ILJ8/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Bovine",
            "common_name": "Bovine"
        },
        {
            "uniprot_canonical_ac": "Q54GP8-1",
            "protein_name": "Glutaredoxin",
            "gene_name": "grxA",
            "tax_id": 44689,
            "organism": "Dictyostelium discoideum",
            "sequence": {
                "sequence": "MDKVKALIKAHKLIIFSKTTCPYCISVKDLFKKLKVVPFVVELDLESDGSELQSAAGQISGVRTVPQVFINEKFIGGCDATTKLHSQGKLIPLLQEAGFL",
                "length": 100
            },
            "evidence": [
                {
                    "id": "A0A0R4ILJ8",
                    "url": "https://omabrowser.org/oma/group/A0A0R4ILJ8/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Cellular slime mold",
            "common_name": "Social amoeba"
        },
        {
            "uniprot_canonical_ac": "Q6AXW1-1",
            "protein_name": "Glutaredoxin-2, mitochondrial",
            "gene_name": "Glrx2",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MSWYRAASVGRRLVASGRILAGRRGAAGAAGSGMGNSTSSFWGKSATTPVNQIQETISNNCVVIFSKSSCSYCSMAKKIFHDMNVNYKVVELDMVEYGSQFQEALYKMTGERTVPRIFVNGIFIGGAADTHRLHKEGKLLPLVHQCYLNKSKRKDVE",
                "length": 157
            },
            "evidence": [
                {
                    "id": "FB:FBgn0036820",
                    "url": "https://alliancegenome.org/gene/FB:FBgn0036820#orthology",
                    "database": "AGR"
                },
                {
                    "id": "SGD:S000002921",
                    "url": "https://alliancegenome.org/gene/SGD:S000002921#orthology",
                    "database": "AGR"
                },
                {
                    "id": "FB:FBgn0034658",
                    "url": "https://alliancegenome.org/gene/FB:FBgn0034658#orthology",
                    "database": "AGR"
                },
                {
                    "id": "SGD:S000000540",
                    "url": "https://alliancegenome.org/gene/SGD:S000000540#orthology",
                    "database": "AGR"
                },
                {
                    "id": "MGI:1916617",
                    "url": "https://alliancegenome.org/gene/MGI:1916617#orthology",
                    "database": "AGR"
                },
                {
                    "id": "ZFIN:ZDB-GENE-040718-101",
                    "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-101#orthology",
                    "database": "AGR"
                },
                {
                    "id": "RGD:1307950",
                    "url": "https://alliancegenome.org/gene/RGD:1307950#orthology",
                    "database": "AGR"
                },
                {
                    "id": "HGNC:16065",
                    "url": "https://alliancegenome.org/gene/HGNC:16065#orthology",
                    "database": "AGR"
                },
                {
                    "id": "A0A0R4ILJ8",
                    "url": "https://omabrowser.org/oma/group/A0A0R4ILJ8/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Rat",
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q8LFQ6-1",
            "protein_name": "Glutaredoxin-C4",
            "gene_name": "GRXC4",
            "tax_id": 3702,
            "organism": "Arabidopsis thaliana",
            "sequence": {
                "sequence": "MTMFRSISMVMLLVALVTFISMVSSAASSPEADFVKKTISSHKIVIFSKSYCPYCKKAKSVFRELDQVPYVVELDEREDGWSIQTALGEIVGRRTVPQVFINGKHLGGSDDTVDAYESGELAKLLGVSGNKEAEL",
                "length": 135
            },
            "evidence": [
                {
                    "id": "A0A0R4ILJ8",
                    "url": "https://omabrowser.org/oma/group/A0A0R4ILJ8/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Arabidopsis",
            "common_name": "Mouse-ear cress"
        },
        {
            "uniprot_canonical_ac": "Q923X4-1",
            "protein_name": "Glutaredoxin-2, mitochondrial",
            "gene_name": "Glrx2",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MSWRRAASVGRRLVASGRILAGRRGAAGAAGSGMGNSTSSFWGKSTTTPVNQIQETISNNCVVIFSKTSCSYCSMAKKIFHDMNVNYKAVELDMLEYGNQFQDALHKMTGERTVPRIFVNGRFIGGAADTHRLHKEGKLLPLVHQCYLKKKQEERH",
                "length": 156
            },
            "evidence": [
                {
                    "id": "FB:FBgn0036820",
                    "url": "https://alliancegenome.org/gene/FB:FBgn0036820#orthology",
                    "database": "AGR"
                },
                {
                    "id": "SGD:S000002921",
                    "url": "https://alliancegenome.org/gene/SGD:S000002921#orthology",
                    "database": "AGR"
                },
                {
                    "id": "FB:FBgn0034658",
                    "url": "https://alliancegenome.org/gene/FB:FBgn0034658#orthology",
                    "database": "AGR"
                },
                {
                    "id": "SGD:S000000540",
                    "url": "https://alliancegenome.org/gene/SGD:S000000540#orthology",
                    "database": "AGR"
                },
                {
                    "id": "MGI:1916617",
                    "url": "https://alliancegenome.org/gene/MGI:1916617#orthology",
                    "database": "AGR"
                },
                {
                    "id": "ZFIN:ZDB-GENE-040718-101",
                    "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-101#orthology",
                    "database": "AGR"
                },
                {
                    "id": "RGD:1307950",
                    "url": "https://alliancegenome.org/gene/RGD:1307950#orthology",
                    "database": "AGR"
                },
                {
                    "id": "HGNC:16065",
                    "url": "https://alliancegenome.org/gene/HGNC:16065#orthology",
                    "database": "AGR"
                },
                {
                    "id": "A0A0R4ILJ8",
                    "url": "https://omabrowser.org/oma/group/A0A0R4ILJ8/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Mouse",
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q9NS18-1",
            "protein_name": "Glutaredoxin-2, mitochondrial",
            "gene_name": "GLRX2",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MIWRRAALAGTRLVWSRSGSAGWLDRAAGAAGAAAAAASGMESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQCYLKKSKRKEFQ",
                "length": 164
            },
            "evidence": [
                {
                    "id": "FB:FBgn0036820",
                    "url": "https://alliancegenome.org/gene/FB:FBgn0036820#orthology",
                    "database": "AGR"
                },
                {
                    "id": "SGD:S000002921",
                    "url": "https://alliancegenome.org/gene/SGD:S000002921#orthology",
                    "database": "AGR"
                },
                {
                    "id": "FB:FBgn0034658",
                    "url": "https://alliancegenome.org/gene/FB:FBgn0034658#orthology",
                    "database": "AGR"
                },
                {
                    "id": "SGD:S000000540",
                    "url": "https://alliancegenome.org/gene/SGD:S000000540#orthology",
                    "database": "AGR"
                },
                {
                    "id": "MGI:1916617",
                    "url": "https://alliancegenome.org/gene/MGI:1916617#orthology",
                    "database": "AGR"
                },
                {
                    "id": "ZFIN:ZDB-GENE-040718-101",
                    "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-101#orthology",
                    "database": "AGR"
                },
                {
                    "id": "RGD:1307950",
                    "url": "https://alliancegenome.org/gene/RGD:1307950#orthology",
                    "database": "AGR"
                },
                {
                    "id": "HGNC:16065",
                    "url": "https://alliancegenome.org/gene/HGNC:16065#orthology",
                    "database": "AGR"
                },
                {
                    "id": "A0A0R4ILJ8",
                    "url": "https://omabrowser.org/oma/group/A0A0R4ILJ8/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Human",
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9VVT6-1",
            "protein_name": "Glutaredoxin 1, isoform A",
            "gene_name": "Grx1",
            "tax_id": 7227,
            "organism": "Drosophila melanogaster",
            "sequence": {
                "sequence": "MGAVGSALRSPIVDMSTKQAKFVENTIASNKVVIFSKTYCPYCTMAKEPFKKLNVDATIIELDGNPDGNEIQAVLGEITGARTVPRVFIDGKFIGGGTDIKRMFETGALQKYFQ",
                "length": 114
            },
            "evidence": [
                {
                    "id": "FB:FBgn0036820",
                    "url": "https://alliancegenome.org/gene/FB:FBgn0036820#orthology",
                    "database": "AGR"
                },
                {
                    "id": "SGD:S000002921",
                    "url": "https://alliancegenome.org/gene/SGD:S000002921#orthology",
                    "database": "AGR"
                },
                {
                    "id": "SGD:S000000540",
                    "url": "https://alliancegenome.org/gene/SGD:S000000540#orthology",
                    "database": "AGR"
                },
                {
                    "id": "MGI:1916617",
                    "url": "https://alliancegenome.org/gene/MGI:1916617#orthology",
                    "database": "AGR"
                },
                {
                    "id": "ZFIN:ZDB-GENE-040718-101",
                    "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-101#orthology",
                    "database": "AGR"
                },
                {
                    "id": "RGD:1307950",
                    "url": "https://alliancegenome.org/gene/RGD:1307950#orthology",
                    "database": "AGR"
                },
                {
                    "id": "HGNC:16065",
                    "url": "https://alliancegenome.org/gene/HGNC:16065#orthology",
                    "database": "AGR"
                }
            ],
            "glygen_name": "Fruit fly",
            "common_name": "Fruit fly"
        },
        {
            "uniprot_canonical_ac": "Q9W2D1-1",
            "protein_name": "MIP32457p1",
            "gene_name": "Grx1t",
            "tax_id": 7227,
            "organism": "Drosophila melanogaster",
            "sequence": {
                "sequence": "MGTVVSTLQRPTLYVSMDSSHAQFVRDTISGNKVVIFSKSYCPYCSMAKEQFRKINVKATVIELDQRDDGNEIQAVLGEMTGSRTVPRCFIDGKFVGGGTDVKRLYEQGILQKYFQ",
                "length": 116
            },
            "evidence": [
                {
                    "id": "SGD:S000002921",
                    "url": "https://alliancegenome.org/gene/SGD:S000002921#orthology",
                    "database": "AGR"
                },
                {
                    "id": "FB:FBgn0034658",
                    "url": "https://alliancegenome.org/gene/FB:FBgn0034658#orthology",
                    "database": "AGR"
                },
                {
                    "id": "SGD:S000000540",
                    "url": "https://alliancegenome.org/gene/SGD:S000000540#orthology",
                    "database": "AGR"
                },
                {
                    "id": "MGI:1916617",
                    "url": "https://alliancegenome.org/gene/MGI:1916617#orthology",
                    "database": "AGR"
                },
                {
                    "id": "ZFIN:ZDB-GENE-040718-101",
                    "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-101#orthology",
                    "database": "AGR"
                },
                {
                    "id": "RGD:1307950",
                    "url": "https://alliancegenome.org/gene/RGD:1307950#orthology",
                    "database": "AGR"
                },
                {
                    "id": "HGNC:16065",
                    "url": "https://alliancegenome.org/gene/HGNC:16065#orthology",
                    "database": "AGR"
                },
                {
                    "id": "A0A0R4ILJ8",
                    "url": "https://omabrowser.org/oma/group/A0A0R4ILJ8/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Fruit fly",
            "common_name": "Fruit fly"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 4,
                "go_terms": [
                    {
                        "name": "glutathione disulfide oxidoreductase activity",
                        "id": "GO:0015038",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015038",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4ILJ8",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "metal ion binding",
                        "id": "GO:0046872",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4ILJ8",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "2 iron, 2 sulfur cluster binding",
                        "id": "GO:0051537",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4ILJ8",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "oxidoreductase activity",
                        "id": "GO:0016491",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4ILJ8",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 4,
                "go_terms": [
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4ILJ8",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitochondrion",
                        "id": "GO:0005739",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4ILJ8",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytosol",
                        "id": "GO:0005829",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4ILJ8",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4ILJ8",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 7,
                "go_terms": [
                    {
                        "name": "central nervous system development",
                        "id": "GO:0007417",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4ILJ8",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "neural crest cell migration",
                        "id": "GO:0001755",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4ILJ8",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to oxidative stress",
                        "id": "GO:0034599",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4ILJ8",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "vasculature development",
                        "id": "GO:0001944",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001944",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4ILJ8",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "heart formation",
                        "id": "GO:0060914",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060914",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4ILJ8",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glial cell migration",
                        "id": "GO:0008347",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008347",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4ILJ8",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "neural crest cell migration involved in heart formation",
                        "id": "GO:0003147",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003147",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4ILJ8",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4ILJ8"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 155,
            "end_pos": 157,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 39,
            "end_pos": 41,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "structures": [],
    "synthesized_glycans": [],
    "enzyme_annotation": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        },
        {
            "name": "homologset.agr",
            "label": "AGR Homologs"
        }
    ],
    "sequence_features": {
        "n_linked_sites": [],
        "o_linked_sites": [],
        "snv_sites": [],
        "glycation_sites": [],
        "phosphorylation_sites": [],
        "sequon_annotation_sites": [
            {
                "start_pos": 155,
                "end_pos": 157
            },
            {
                "start_pos": 39,
                "end_pos": 41
            }
        ]
    },
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}