{
    "uniprot_canonical_ac": "A0A0R4IJS9-1",
    "uniprot_ac": "A0A0R4IJS9",
    "uniprot_id": "A0A0R4IJS9_DANRE",
    "mass": {
        "chemical_mass": 34725.0,
        "monoisotopic_mass": 34725.0
    },
    "refseq": {
        "ac": "NP_001230273",
        "name": "forkhead box protein Q1a",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230273"
    },
    "gene_names": [
        {
            "name": "foxq1a",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0R4IJS9",
            "id": "A0A0R4IJS9"
        },
        {
            "name": "foxq1a",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230273",
            "id": "NP_001230273"
        },
        {
            "name": "foxq1l; zgc:162905",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230273",
            "id": "NP_001230273"
        },
        {
            "name": "foxq1l",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0R4IJS9",
            "id": "A0A0R4IJS9"
        },
        {
            "name": "zgc:162905",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0R4IJS9",
            "id": "A0A0R4IJS9"
        }
    ],
    "protein_names": [
        {
            "name": "Forkhead box Q1a",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprotkb/A0A0R4IJS9/entry#names_and_taxonomy",
            "id": "A0A0R4IJS9"
        },
        {
            "name": "forkhead box protein Q1a",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230273",
            "id": "NP_001230273"
        }
    ],
    "function": [
        {
            "annotation": "This study provides the first genetic mutant analyses of zebrafish foxq1a and foxq1b. Foxq1a, but not foxq1b, was transcriptionally regulated during a bacterial response, while the expression of foxq1a was detected in sorted macrophages and upregulated in foxq1a-deficient mutants. Publication Status: Online-Only",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001230273",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230273"
                },
                {
                    "database": "PubMed",
                    "id": "29534099",
                    "url": "https://glygen.org/publication/PubMed/29534099"
                }
            ]
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    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Danio rerio",
            "taxid": 7955,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0R4IJS9",
                    "url": "https://www.uniprot.org/uniprot/A0A0R4IJS9"
                }
            ],
            "common_name": "Zebrafish",
            "glygen_name": "Zebrafish",
            "reference_species": "Danio rerio [7955]"
        }
    ],
    "gene": [
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            "name": "foxq1a",
            "url": "https://www.uniprot.org/uniprot/A0A0R4IJS9",
            "locus": {}
        }
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        {
            "id": "ZFIN:ZDB-GENE-070424-74",
            "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-74",
            "database": "AGR",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "ENSDARG00000030896",
            "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000030896",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd20034",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20034",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "100537750",
            "url": "https://www.ncbi.nlm.nih.gov/gene/100537750",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR001766",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018122",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018122",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR030456",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR030456",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036388",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036390",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR047518",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR047518",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR050211",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR050211",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dre:100537750",
            "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100537750",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "FHIDSYA",
            "url": "https://omabrowser.org/oma/group/FHIDSYA/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "A0A0R4IJS9",
            "url": "https://www.orthodb.org/?gene=A0A0R4IJS9",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11829",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11829",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11829:SF385",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11829:SF385",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00250",
            "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001230273",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230273",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0R4IJS9",
            "url": "https://www.uniprot.org/uniprot/A0A0R4IJS9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0R4IJS9-1",
            "url": "https://www.uniprot.org/uniprot/A0A0R4IJS9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "ZDB-GENE-070424-74",
            "url": "https://zfin.org/ZDB-GENE-070424-74",
            "database": "ZFIN",
            "categories": [
                "Protein",
                "Organism-specific"
            ]
        }
    ],
    "sequence": {
        "sequence": "MSMHSSSATGSYTALSLFELSEALPMKLEVFCGSHYDSKPAELCSDAEGSIPSPVSAEEELGSDGDCVAHSPAPVADTKGKPYTRRPKPPYSYIALIAMAIRDSNSGRLTLAEINDYLMKKFPFFRGSYTGWRNSVRHNLSLNDCFLKVLRDPSRPWGKDNYWMLNPHSEYTFADGVFRRRRKRISKKTGREPEGPVQTHALDSNDSIATPPSSGKFTSSFAIESILSRPFRREDRPVLSPDTWPGGVDTVLPYVMLRSYGALEDPSMSRRQRDFFAFQLPPECLSIPHTSAAVPAPATAGYHPFKIDYLLS",
        "length": 312,
        "header": "tr|A0A0R4IJS9-1|A0A0R4IJS9_DANRE Isoform 1 of Forkhead box Q1a  OS=Danio rerio OX=7955 GN=foxq1a PE=4 SV=1 CANONICAL=A0A0R4IJS9-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0R4IJS9-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A0R4IJS9/entry#A0A0R4IJS9-1",
            "sequence": {
                "sequence": "MSMHSSSATGSYTALSLFELSEALPMKLEVFCGSHYDSKPAELCSDAEGSIPSPVSAEEELGSDGDCVAHSPAPVADTKGKPYTRRPKPPYSYIALIAMAIRDSNSGRLTLAEINDYLMKKFPFFRGSYTGWRNSVRHNLSLNDCFLKVLRDPSRPWGKDNYWMLNPHSEYTFADGVFRRRRKRISKKTGREPEGPVQTHALDSNDSIATPPSSGKFTSSFAIESILSRPFRREDRPVLSPDTWPGGVDTVLPYVMLRSYGALEDPSMSRRQRDFFAFQLPPECLSIPHTSAAVPAPATAGYHPFKIDYLLS",
                "length": 312,
                "header": "tr|A0A0R4IJS9-1|A0A0R4IJS9_DANRE Isoform 1 of Forkhead box Q1a  OS=Danio rerio OX=7955 GN=foxq1a PE=4 SV=1 CANONICAL=A0A0R4IJS9-1"
            },
            "locus": {}
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Genetic analysis of zebrafish homologs of human FOXQ1, foxq1a and foxq1b, in innate immune cell development and bacterial host response.",
            "journal": "PloS one",
            "date": "2018",
            "authors": "Earley Alison M, Dixon Cameron T, Shiau Celia E",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001230273",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230273"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "29534099",
                    "url": "https://glygen.org/publication/PubMed/29534099"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "dre:100537750",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100537750",
            "resource": "KEGG Pathway"
        }
    ],
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        {
            "uniprot_canonical_ac": "O70220-1",
            "protein_name": "Forkhead box protein Q1",
            "gene_name": "Foxq1",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MKLEVFVPRAAHGDKMGSDLEGAGSSDVPSPLSAAGDDSLGSDGDCAANSPAAGSGAGDLEGGGGERNSSGGPSAQDGPEATDDSRTQASAAGPCAGGVGGGEGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHRTTVSASGLRPEEAPPGPAGTPQPAPAARSSPIARSPARQEERSSPASKFSSSFAIDSILSKPFRSRRDGDSALGVQLPWGAAPCPPLRAYPALLPAAPGGALLPLCAYGASEPTLLASRGTEVQPAAPLLLAPLSTAAPAKPFRGPETAGAAHLYCPLRLPTALQAAAACGPGPHLSYPVETLLA",
                "length": 400
            },
            "evidence": [
                {
                    "id": "HGNC:20951",
                    "url": "https://alliancegenome.org/gene/HGNC:20951#orthology",
                    "database": "AGR"
                },
                {
                    "id": "MGI:1298228",
                    "url": "https://alliancegenome.org/gene/MGI:1298228#orthology",
                    "database": "AGR"
                },
                {
                    "id": "ZFIN:ZDB-GENE-070424-74",
                    "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-74#orthology",
                    "database": "AGR"
                },
                {
                    "id": "RGD:621572",
                    "url": "https://alliancegenome.org/gene/RGD:621572#orthology",
                    "database": "AGR"
                }
            ],
            "glygen_name": "Mouse",
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q63244-1",
            "protein_name": "Forkhead box protein Q1",
            "gene_name": "Foxq1",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MKLEVFAPRAAHGDKMGSDLEGAGSSDVPSPLSAAGDDSLGSDGDCAANSPAAGSGAGDLEGGGGERNSSGGASTQDDPEVTDGSRTQASPVGPCAGSVGGGEGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHRTTVSASGYGGGSPPGPAGTPQPAPTAGSSPIARSPARQEEGSSPASKFSSSFAIDSILSKPFRSRRDGTPALGVQLPWSAAPCPPLRAYPALLPASSGGALLPLCAYGAAEPTLLASRGAEVQPAAPLFVAPLSTAAPAKPFRGPETAGAAHLYCPLRLPTALQAAAACGPGPHLSYRVETLLA",
                "length": 399
            },
            "evidence": [
                {
                    "id": "HGNC:20951",
                    "url": "https://alliancegenome.org/gene/HGNC:20951#orthology",
                    "database": "AGR"
                },
                {
                    "id": "MGI:1298228",
                    "url": "https://alliancegenome.org/gene/MGI:1298228#orthology",
                    "database": "AGR"
                },
                {
                    "id": "ZFIN:ZDB-GENE-070424-74",
                    "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-74#orthology",
                    "database": "AGR"
                },
                {
                    "id": "RGD:621572",
                    "url": "https://alliancegenome.org/gene/RGD:621572#orthology",
                    "database": "AGR"
                }
            ],
            "glygen_name": "Rat",
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q6NXD5-1",
            "protein_name": "Forkhead box protein Q1",
            "gene_name": "foxq1b",
            "tax_id": 7955,
            "organism": "Danio rerio",
            "sequence": {
                "sequence": "MDANVASPLSTEEELGSDGDCSANSPGPGAPVPDGKAKPYTRRPKPPYSYIALIAMAIRDSNTGRLTLAEINEYLMKKFPFFRGSYTGWRNSVRHNLSLNDCFLKVLRDPSRPWGKDNYWMLNPHSEYTFADGVFRRRRKRISKKILGSAESPERVPADDSRLPARDESVSKFSSSFAIDSILSKPFMRREQSTDDTCFGTTRLMMSAAPHFLPVAMGFPPQSRFQVSSEVSNVFPIYRCNTADISNISRMADIQSSLPGLAHSHTTLQEAGFHPFRIDSLLS",
                "length": 283
            },
            "evidence": [
                {
                    "id": "HGNC:20951",
                    "url": "https://alliancegenome.org/gene/HGNC:20951#orthology",
                    "database": "AGR"
                },
                {
                    "id": "MGI:1298228",
                    "url": "https://alliancegenome.org/gene/MGI:1298228#orthology",
                    "database": "AGR"
                },
                {
                    "id": "RGD:621572",
                    "url": "https://alliancegenome.org/gene/RGD:621572#orthology",
                    "database": "AGR"
                }
            ],
            "glygen_name": "Zebrafish",
            "common_name": "Zebrafish"
        },
        {
            "uniprot_canonical_ac": "Q9C009-1",
            "protein_name": "Forkhead box protein Q1",
            "gene_name": "FOXQ1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MKLEVFVPRAAHGDKQGSDLEGAGGSDAPSPLSAAGDDSLGSDGDCAANSPAAGGGARDTQGDGEQSAGGGPGAEEAIPAAAAAAVVAEGAEAGAAGPGAGGAGSGEGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHRAPVPAPGLRPEEAPGLPAAPPPAPAAPASPRMRSPARQEERASPAGKFSSSFAIDSILRKPFRSRRLRDTAPGTTLQWGAAPCPPLPAFPALLPAAPCRALLPLCAYGAGEPARLGAREAEVPPTAPPLLLAPLPAAAPAKPLRGPAAGGAHLYCPLRLPAALQAASVRRPGPHLPYPVETLLA",
                "length": 403
            },
            "evidence": [
                {
                    "id": "HGNC:20951",
                    "url": "https://alliancegenome.org/gene/HGNC:20951#orthology",
                    "database": "AGR"
                },
                {
                    "id": "MGI:1298228",
                    "url": "https://alliancegenome.org/gene/MGI:1298228#orthology",
                    "database": "AGR"
                },
                {
                    "id": "ZFIN:ZDB-GENE-070424-74",
                    "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-74#orthology",
                    "database": "AGR"
                },
                {
                    "id": "RGD:621572",
                    "url": "https://alliancegenome.org/gene/RGD:621572#orthology",
                    "database": "AGR"
                }
            ],
            "glygen_name": "Human",
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4IJS9",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4IJS9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 5,
                "go_terms": [
                    {
                        "name": "regulation of transcription by RNA polymerase II",
                        "id": "GO:0006357",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4IJS9",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4IJS9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell differentiation",
                        "id": "GO:0030154",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4IJS9",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4IJS9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to xenobiotic stimulus",
                        "id": "GO:0009410",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4IJS9",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4IJS9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "tissue development",
                        "id": "GO:0009888",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4IJS9",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4IJS9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "anatomical structure morphogenesis",
                        "id": "GO:0009653",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4IJS9",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4IJS9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding",
                        "id": "GO:0000978",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4IJS9",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4IJS9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "DNA-binding transcription factor activity, RNA polymerase II-specific",
                        "id": "GO:0000981",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0R4IJS9",
                                "url": "https://www.uniprot.org/uniprot/A0A0R4IJS9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 139,
            "end_pos": 141,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 205,
            "end_pos": 207,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "structures": [],
    "synthesized_glycans": [],
    "enzyme_annotation": [],
    "cluster_types": [
        {
            "name": "homologset.agr",
            "label": "AGR Homologs"
        }
    ],
    "sequence_features": {
        "n_linked_sites": [],
        "o_linked_sites": [],
        "snv_sites": [],
        "glycation_sites": [],
        "phosphorylation_sites": [],
        "sequon_annotation_sites": [
            {
                "start_pos": 139,
                "end_pos": 141
            },
            {
                "start_pos": 205,
                "end_pos": 207
            }
        ]
    },
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