{
    "uniprot_canonical_ac": "A0A1P8AX50-1",
    "uniprot_ac": "A0A1P8AX50",
    "uniprot_id": "A0A1P8AX50_ARATH",
    "mass": {
        "chemical_mass": 55158.0,
        "monoisotopic_mass": 55158.0
    },
    "refseq": {
        "ac": "NP_001323445",
        "name": "AAA-type ATPase family protein",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001323445"
    },
    "gene_names": [
        {
            "name": "F17K2.3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001323445",
            "id": "NP_001323445"
        },
        {
            "name": "F17K2.3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A1P8AX50",
            "id": "A0A1P8AX50"
        }
    ],
    "protein_names": [
        {
            "name": "microtubule-severing ATPase",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprotkb/A0A1P8AX50/entry#names_and_taxonomy",
            "id": "A0A1P8AX50"
        },
        {
            "name": "5.6.1.1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprotkb/A0A1P8AX50/entry#names_and_taxonomy",
            "id": "A0A1P8AX50"
        },
        {
            "name": "AAA-type ATPase family protein",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001323445",
            "id": "NP_001323445"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Arabidopsis thaliana",
            "taxid": 3702,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A1P8AX50",
                    "url": "https://www.uniprot.org/uniprot/A0A1P8AX50"
                }
            ],
            "common_name": "Mouse-ear cress",
            "glygen_name": "Arabidopsis",
            "reference_species": "Arabidopsis thaliana [3702]"
        }
    ],
    "gene": [
        {
            "name": "",
            "url": "https://www.uniprot.org/uniprot/A0A1P8AX50",
            "locus": {}
        }
    ],
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            "id": "A0A1P8AX50",
            "url": "https://alphafold.ebi.ac.uk/entry/A0A1P8AX50",
            "database": "AlphaFoldDB",
            "categories": []
        },
        {
            "id": "AT2G45500",
            "url": "https://bar.utoronto.ca/thalemine/portal.do?externalids=AT2G45500",
            "database": "Araport",
            "categories": [
                "Protein",
                "Organism-specific"
            ]
        },
        {
            "id": "cd02679",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02679",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd19524",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19524",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "819158",
            "url": "https://www.ncbi.nlm.nih.gov/gene/819158",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR003593",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR003959",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR003960",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003960",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR007330",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007330",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR027417",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR041569",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR041569",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR050304",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR050304",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "ath:AT2G45500",
            "url": "https://www.genome.jp/dbget-bin/www_bget?ath:AT2G45500",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "A0A1P8AX50",
            "url": "https://www.orthodb.org/?gene=A0A1P8AX50",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23074",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23074",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23074:SF86",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23074:SF86",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00004",
            "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF17862",
            "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17862",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001323445",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001323445",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "AT2G45500",
            "url": "https://www.arabidopsis.org/servlets/TairObject?type=locus&name=AT2G45500",
            "database": "TAIR",
            "categories": [
                "Protein",
                "Organism-specific"
            ]
        },
        {
            "id": "A0A1P8AX27",
            "url": "https://www.uniprot.org/uniprot/A0A1P8AX27",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A1P8AX27-1",
            "url": "https://www.uniprot.org/uniprot/A0A1P8AX27-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A1P8AX50",
            "url": "https://www.uniprot.org/uniprot/A0A1P8AX50",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A1P8AX50-1",
            "url": "https://www.uniprot.org/uniprot/A0A1P8AX50-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A8MRR2",
            "url": "https://www.uniprot.org/uniprot/A8MRR2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A8MRR2-1",
            "url": "https://www.uniprot.org/uniprot/A8MRR2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q0WMJ4",
            "url": "https://www.uniprot.org/uniprot/Q0WMJ4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q0WMJ4-1",
            "url": "https://www.uniprot.org/uniprot/Q0WMJ4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
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        "sequence": "MIDFIVYCLDMSFLRGIIDSFSSILNEESKKDPSVSSSSTSSESMNGIDGVPVTNERIAYKLKGYFDLAKEEIAKGVRAEEWGLHDDALLHYRNAQRIMNEATSTPSPSYISSSEKEKVRSYREKISNWQNQVSERLQALGVGMSENKRTVAYPSSASVSSTASRYRKTLSQKTPVARGGVATPRNPKDAAASPKPVKESGNVYDDKLVEMINTTIVDRSPSVKWDDVAGLNGAKQALLEMVILPAKRRDLFTGLRRPARGLLLFGPPGNGKTMLAKAVASESQATFFNVSASSLTSKWVGEAEKLVKTLFQVAISRQPSVIFMDEIDSIMSTRSTSENEASRRLKSEFLIQFDGVTSNPDDLVIIIGATNKPQELDDAVLRRLVKRIYVPLPDSNVRKLLFKTKLKCQPHSLSDGDIDKIVKETEGYSGSDLQALCEEAAMMPIRELGANILTIQANKVRSLRYDDFRKSMAVIRPSLSKSKWEELERWNSEFGSN",
        "length": 497,
        "header": "tr|A0A1P8AX50-1|A0A1P8AX50_ARATH Isoform 1 of microtubule-severing ATPase  OS=Arabidopsis thaliana OX=3702 GN= PE=1 SV=1 CANONICAL=A0A1P8AX50-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A1P8AX27-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A1P8AX50/entry#A0A1P8AX27-1",
            "sequence": {
                "sequence": "MSENKRTVAYPSSASVSSTASRYRKTLSQKTPVARGGVATPRNPKDAAASPKPVKESGNVYDDKLVEMINTTIVDRSPSVKWDDVAGLNGAKQALLEMVILPAKRRDLFTGLRRPARGLLLFGPPGNGKTMLAKAVASESQATFFNVSASSLTSKWVGEAEKLVKTLFQVAISRQPSVIFMDEIDSIMSTRSTSENEASRRLKSEFLIQFDGVTSNPDDLVIIIGATNKPQELDDAVLRRLVKRIYVPLPDSNVRKLLFKTKLKCQPHSLSDGDIDKIVKETEGYSGSDLQALCEEAAMMPIRELGANILTIQANKVRSLRYDDFRKSMAVIRPSLSKSKWEELERWNSEFGSN",
                "length": 354,
                "header": "tr|A0A1P8AX27-1|A0A1P8AX50_ARATH Computationally mapped isoform of microtubule-severing ATPase  OS=Arabidopsis thaliana OX=3702 GN= PE=1 SV=1 CANONICAL=A0A1P8AX50-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 18752022,
                "end_pos": 18749976,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "AT2G45500.3",
                        "url": "https://www.ensemblgenomes.org/id/AT2G45500.3"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "AT2G45500.3",
                        "url": "https://www.ensemblgenomes.org/id/AT2G45500.3"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A1P8AX50-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A1P8AX50/entry#A0A1P8AX50-1",
            "sequence": {
                "sequence": "MIDFIVYCLDMSFLRGIIDSFSSILNEESKKDPSVSSSSTSSESMNGIDGVPVTNERIAYKLKGYFDLAKEEIAKGVRAEEWGLHDDALLHYRNAQRIMNEATSTPSPSYISSSEKEKVRSYREKISNWQNQVSERLQALGVGMSENKRTVAYPSSASVSSTASRYRKTLSQKTPVARGGVATPRNPKDAAASPKPVKESGNVYDDKLVEMINTTIVDRSPSVKWDDVAGLNGAKQALLEMVILPAKRRDLFTGLRRPARGLLLFGPPGNGKTMLAKAVASESQATFFNVSASSLTSKWVGEAEKLVKTLFQVAISRQPSVIFMDEIDSIMSTRSTSENEASRRLKSEFLIQFDGVTSNPDDLVIIIGATNKPQELDDAVLRRLVKRIYVPLPDSNVRKLLFKTKLKCQPHSLSDGDIDKIVKETEGYSGSDLQALCEEAAMMPIRELGANILTIQANKVRSLRYDDFRKSMAVIRPSLSKSKWEELERWNSEFGSN",
                "length": 497,
                "header": "tr|A0A1P8AX50-1|A0A1P8AX50_ARATH Isoform 1 of microtubule-severing ATPase  OS=Arabidopsis thaliana OX=3702 GN= PE=1 SV=1 CANONICAL=A0A1P8AX50-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 18752666,
                "end_pos": 18749976,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "AT2G45500.5",
                        "url": "https://www.ensemblgenomes.org/id/AT2G45500.5"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "AT2G45500.5",
                        "url": "https://www.ensemblgenomes.org/id/AT2G45500.5"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A8MRR2-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A1P8AX50/entry#A8MRR2-1",
            "sequence": {
                "sequence": "MSFLRGIIDSFSSILNEESKKDPSVSSSSTSSESMNGIDGVPVTNERIAYKLKGYFDLAKEEIAKGVRAEEWGLHDDALLHYRNAQRIMNEATSTPSPSYISSSEKEKVRSYREKISNWQNQVSERLQALGKRTGVGMSENKRTVAYPSSASVSSTASRYRKTLSQKTPVARGGVATPRNPKDAAASPKPVKESGNVYDDKLVEMINTTIVDRSPSVKWDDVAGLNGAKQALLEMVILPAKRRDLFTGLRRPARGLLLFGPPGNGKTMLAKAVASESQATFFNVSASSLTSKWVGEAEKLVKTLFQVAISRQPSVIFMDEIDSIMSTRSTSENEASRRLKSEFLIQFDGVTSNPDDLVIIIGATNKPQELDDAVLRRLVKRIYVPLPDSNVRKLLFKTKLKCQPHSLSDGDIDKIVKETEGYSGSDLQALCEEAAMMPIRELGANILTIQANKVRSLRYDDFRKSMAVIRPSLSKSKWEELERWNSEFGSN",
                "length": 491,
                "header": "tr|A8MRR2-1|A0A1P8AX50_ARATH Computationally mapped isoform of microtubule-severing ATPase  OS=Arabidopsis thaliana OX=3702 GN= PE=1 SV=1 CANONICAL=A0A1P8AX50-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 18752636,
                "end_pos": 18749976,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "AT2G45500.1",
                        "url": "https://www.ensemblgenomes.org/id/AT2G45500.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "AT2G45500.1",
                        "url": "https://www.ensemblgenomes.org/id/AT2G45500.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q0WMJ4-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A1P8AX50/entry#Q0WMJ4-1",
            "sequence": {
                "sequence": "MSFLRGIIDSFSSILNEESKKDPSVSSSSTSSESMNGIDGVPVTNERIAYKLKGYFDLAKEEIAKGVRAEEWGLHDDALLHYRNAQRIMNEATSTPSPSYISSSEKEKVRSYREKISNWQNQVSERLQALGVGMSENKRTVAYPSSASVSSTASRYRKTLSQKTPVARGGVATPRNPKDAAASPKPVKESGNVYDDKLVEMINTTIVDRSPSVKWDDVAGLNGAKQALLEMVILPAKRRDLFTGLRRPARGLLLFGPPGNGKTMLAKAVASESQATFFNVSASSLTSKWVGEAEKLVKTLFQVAISRQPSVIFMDEIDSIMSTRSTSENEASRRLKSEFLIQFDGVTSNPDDLVIIIGATNKPQELDDAVLRRLVKRIYVPLPDSNVRKLLFKTKLKCQPHSLSDGDIDKIVKETEGYSGSDLQALCEEAAMMPIRELGANILTIQANKVRSLRYDDFRKSMAVIRPSLSKSKWEELERWNSEFGSN",
                "length": 487,
                "header": "tr|Q0WMJ4-1|A0A1P8AX50_ARATH Computationally mapped isoform of microtubule-severing ATPase  OS=Arabidopsis thaliana OX=3702 GN= PE=1 SV=1 CANONICAL=A0A1P8AX50-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 18752636,
                "end_pos": 18749976,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "AT2G45500.2",
                        "url": "https://www.ensemblgenomes.org/id/AT2G45500.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "AT2G45500.2",
                        "url": "https://www.ensemblgenomes.org/id/AT2G45500.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "enzyme"
    ],
    "publication": [
        {
            "title": "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.",
            "journal": "Nature",
            "date": "1999",
            "authors": "Lin X, Kaul S, Rounsley S, Shea T P, Benito M I, Town C D, Fujii C Y, Mason T, Bowman C L, Barnstead M, Feldblyum T V, Buell C R, Ketchum K A, Lee J, Ronning C M, Koo H L, Moffat K S, Cronin L A, Shen M, Pai G, Van Aken S, Umayam L, Tallon L J, Gill J E, Adams M D, Carrera A J, Creasy T H, Goodman H M, Somerville C R, Copenhaver G P, Preuss D, Nierman W C, White O, Eisen J A, Salzberg S L, Fraser C M, Venter J C",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A8MRR2",
                    "url": "https://www.uniprot.org/uniprot/A8MRR2"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "10617197",
                    "url": "https://glygen.org/publication/PubMed/10617197"
                }
            ]
        },
        {
            "title": "Araport11: a complete reannotation of the Arabidopsis thaliana reference genome.",
            "journal": "Plant J.",
            "date": "2017",
            "authors": "Cheng Chia-Yi, Krishnakumar Vivek, Chan Agnes P, Thibaud-Nissen Fran\u00e7oise, Schobel Seth, Town Christopher D",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A8MRR2",
                    "url": "https://www.uniprot.org/uniprot/A8MRR2"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "27862469",
                    "url": "https://glygen.org/publication/PubMed/27862469"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "ath:AT2G45500",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/www_bget?ath:AT2G45500",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 3,
                "go_terms": [
                    {
                        "name": "ATP binding",
                        "id": "GO:0005524",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1P8AX50",
                                "url": "https://www.uniprot.org/uniprot/A0A1P8AX50"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ATP hydrolysis activity",
                        "id": "GO:0016887",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1P8AX50",
                                "url": "https://www.uniprot.org/uniprot/A0A1P8AX50"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "isomerase activity",
                        "id": "GO:0016853",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016853",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1P8AX50",
                                "url": "https://www.uniprot.org/uniprot/A0A1P8AX50"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "microtubule",
                        "id": "GO:0005874",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1P8AX50",
                                "url": "https://www.uniprot.org/uniprot/A0A1P8AX50"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "microtubule cytoskeleton",
                        "id": "GO:0015630",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1P8AX50",
                                "url": "https://www.uniprot.org/uniprot/A0A1P8AX50"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 1,
                "go_terms": [
                    {
                        "name": "microtubule cytoskeleton organization",
                        "id": "GO:0000226",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A1P8AX50",
                                "url": "https://www.uniprot.org/uniprot/A0A1P8AX50"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 213,
            "end_pos": 215,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 289,
            "end_pos": 291,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "structures": [
        {
            "pdb_id": "AF-A0A1P8AX50-F1",
            "pdb_chain": "global",
            "start_pos": 1,
            "end_pos": 497,
            "overlap": "1.0",
            "method": "AlphaFold",
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