{ "uniprot_canonical_ac": "A0A1D5Q032-1", "uniprot_ac": "A0A1D5Q032", "uniprot_id": "A0A1D5Q032_CHICK", "mass": { "chemical_mass": 51079.0, "monoisotopic_mass": 51079.0 }, "refseq": {}, "gene_names": [ { "name": "CAP1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A1D5Q032", "id": "A0A1D5Q032" } ], "protein_names": [ { "name": "Adenylyl cyclase-associated protein", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A0A1D5Q032/entry#names_and_taxonomy", "id": "A0A1D5Q032" } ], "function": [ { "annotation": "Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5Q032", "url": "https://www.uniprot.org/uniprot/A0A1D5Q032#function" }, { "database": "UniProtKB", "id": "ARBA00003250", "url": 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"categories": [ "Gene Expression" ] }, { "id": "IPR001837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TASECQQ", "url": "https://omabrowser.org/oma/group/TASECQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10652", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10652", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10652:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10652:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01213", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01213", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF08603", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08603", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "XP_015153403", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153403", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5Q032", "url": "https://www.uniprot.org/uniprot/A0A1D5Q032", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5Q032-1", "url": "https://www.uniprot.org/uniprot/A0A1D5Q032-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERLVERLERAVERLETVCQGPGMCGDGSSPGVAQYVQAFDAILSGPVAEYINISKEVGGDVQKHAEMVHAGFMTERSLLVTASQHQQPSENVFSTLLKPISEQIQMVQNLREKNRGSKQFNHLSAVSESIPALGWVAMSPKPGPYVKEMTDAAMFYTNRILKEYKDVDKKQVDWVKAYLRIWTELQAYIKEYHTTGLTWSKTGPVATEGAKAPSTAPTGAAPPPPGPPPPPAPSHPSSGADDSATRSALFAQINRGEGITSGLRHVSDDMKTHKNPALKNQGGPIRSGPKPFTSPKPACSVNPSQKTSPKQPALLELEGKKWRVENQENATNLVISDTELKQVAYVFKCTNSTLQIKGKINSITLDNCKKLGLVFDDVVGIVEIINSRDIKVQVMGKVPTISINKTDGCHVYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFTEFPVPEQFKTVWNGQKLVTTVTEIAG", "length": 469, "header": "tr|A0A1D5Q032-1|A0A1D5Q032_CHICK Isoform 1 of Adenylyl cyclase-associated protein OS=Gallus gallus OX=9031 GN=CAP1 PE=1 SV=2 CANONICAL=A0A1D5Q032-1" }, "isoforms": [ { "isoform_ac": "A0A1D5Q032-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5Q032/entry#A0A1D5Q032-1", "sequence": { "sequence": "MERLVERLERAVERLETVCQGPGMCGDGSSPGVAQYVQAFDAILSGPVAEYINISKEVGGDVQKHAEMVHAGFMTERSLLVTASQHQQPSENVFSTLLKPISEQIQMVQNLREKNRGSKQFNHLSAVSESIPALGWVAMSPKPGPYVKEMTDAAMFYTNRILKEYKDVDKKQVDWVKAYLRIWTELQAYIKEYHTTGLTWSKTGPVATEGAKAPSTAPTGAAPPPPGPPPPPAPSHPSSGADDSATRSALFAQINRGEGITSGLRHVSDDMKTHKNPALKNQGGPIRSGPKPFTSPKPACSVNPSQKTSPKQPALLELEGKKWRVENQENATNLVISDTELKQVAYVFKCTNSTLQIKGKINSITLDNCKKLGLVFDDVVGIVEIINSRDIKVQVMGKVPTISINKTDGCHVYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFTEFPVPEQFKTVWNGQKLVTTVTEIAG", "length": 469, "header": "tr|A0A1D5Q032-1|A0A1D5Q032_CHICK Isoform 1 of Adenylyl cyclase-associated protein OS=Gallus gallus OX=9031 GN=CAP1 PE=1 SV=2 CANONICAL=A0A1D5Q032-1" }, "locus": { "chromosome": "23", "start_pos": 5922746, "end_pos": 5916516, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036362.1", "url": "https://www.ensembl.org/id/ENSGALT00010036362.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021151.1", "url": "https://www.ensembl.org/id/ENSGALP00010021151.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "Neutrophil degranulation", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5Q032", "url": "https://www.uniprot.org/uniprot/A0A1D5Q032" } ], "pmid": "" }, { "name": "adenylate cyclase binding", "id": "GO:0008179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008179", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5Q032", "url": "https://www.uniprot.org/uniprot/A0A1D5Q032" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5Q032", "url": "https://www.uniprot.org/uniprot/A0A1D5Q032" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5Q032", "url": "https://www.uniprot.org/uniprot/A0A1D5Q032" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5Q032", "url": "https://www.uniprot.org/uniprot/A0A1D5Q032" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5Q032", "url": "https://www.uniprot.org/uniprot/A0A1D5Q032" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5Q032", "url": "https://www.uniprot.org/uniprot/A0A1D5Q032" } ], "pmid": "" }, { "name": "cAMP-mediated signaling", "id": "GO:0019933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019933", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5Q032", "url": "https://www.uniprot.org/uniprot/A0A1D5Q032" } ], "pmid": "" }, { "name": "receptor-mediated endocytosis", "id": "GO:0006898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5Q032", "url": "https://www.uniprot.org/uniprot/A0A1D5Q032" } ], "pmid": "" }, { "name": "ameboidal-type cell migration", "id": "GO:0001667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001667", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5Q032", "url": "https://www.uniprot.org/uniprot/A0A1D5Q032" } ], "pmid": "" } ] } ] }, 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